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Deliberate Integration of Student Leadership Development in Doctor of Pharmacy Programs.

American journal of pharmaceutical education

Janke KK, Nelson MH, Bzowyckyj AS, Fuentes DG, Rosenberg E, DiCenzo R.
PMID: 26941428
Am J Pharm Educ. 2016 Feb 25;80(1):2. doi: 10.5688/ajpe8012.

The CAPE 2013 Outcomes answered the call for increased student leadership development (SLD) by identifying leadership as a desired curricular goal. To meet this outcome, colleges and schools of pharmacy are advised to first identify a set of SLD...

Understanding a Hydroformylation Catalyst that Produces Branched Aldehydes from Alkyl Alkenes.

Journal of the American Chemical Society

Dingwall P, Fuentes JA, Crawford, Slawin AMZ, Bühl M, Clarke ML.
PMID: 29068679
J Am Chem Soc. 2017 Nov 08;139(44):15921-15932. doi: 10.1021/jacs.7b09164. Epub 2017 Oct 25.

This paper reports experimental and computational studies on the mechanism of a rhodium-catalyzed hydroformylation that is selective for branched aldehyde products from unbiased alkene substrates. This highly unusual selectivity relies on a phospholane-phosphite ligand prosaically called BOBPHOS. Kinetic studies...

Iatrogenic T-Cell Lymphoma with Associated Hemophagocytic Lymphohistiocyotsis in a Patient with Long-Standing Rheumatoid Arthritis.

Case reports in hematology

Andrade XA, Fuentes HE, Oramas DM, Mann H, Kovarik P.
PMID: 29515924
Case Rep Hematol. 2018 Jan 11;2018:8097965. doi: 10.1155/2018/8097965. eCollection 2018.

Patients with rheumatoid arthritis are at increased risk of hematological malignancies, especially when exposed to immunosuppressive therapy. The mechanisms of lymphomagenesis remain poorly understood but factors implicated include high disease activity, exposure to antitumoral necrosis factor medications, and Epstein-Barr...

A Simple PB/LIE Free Energy Function Accurately Predicts the Peptide Binding Specificity of the Tiam1 PDZ Domain.

Frontiers in molecular biosciences

Panel N, Sun YJ, Fuentes EJ, Simonson T.
PMID: 29018806
Front Mol Biosci. 2017 Sep 26;4:65. doi: 10.3389/fmolb.2017.00065. eCollection 2017.

PDZ domains generally bind short amino acid sequences at the C-terminus of target proteins, and short peptides can be used as inhibitors or model ligands. Here, we used experimental binding assays and molecular dynamics simulations to characterize 51 complexes...

Relationship between Platelet PPARs, cAMP Levels, and P-Selectin Expression: Antiplatelet Activity of Natural Products.

Evidence-based complementary and alternative medicine : eCAM

Fuentes E, Palomo I.
PMID: 24324520
Evid Based Complement Alternat Med. 2013;2013:861786. doi: 10.1155/2013/861786. Epub 2013 Nov 13.

Platelets are no longer considered simply as cells participating in thrombosis. In atherosclerosis, platelets are regulators of multiple processes, with the recruitment of inflammatory cells towards the lesion sites, inflammatory mediators release, and regulation of endothelial function. The antiplatelet...

Identification of Plant Extracts that Inhibit the Formation of Diabetes-Linked IAPP Amyloid.

Journal of herbal medicine

Fuentes AL, Hennessy K, Pascual J, Pepe N, Wang I, Santiago A, Chaggan C, Martinez J, Rivera E, Cota P, Cunha C, Nogaj LA, Moffet DA.
PMID: 27042401
J Herb Med. 2016 Mar;6(1):37-41. doi: 10.1016/j.hermed.2015.11.001.

The extracts of 27 vegetables, spices and herbs were screened for their functional ability to inhibit the aggregation of islet amyloid polypeptide (IAPP, amylin) into toxic amyloid aggregates. The aggregation of IAPP has been directly linked to the death...

New Strategies for the Synthesis of Fluorinated Vinylogous Amidines and beta-Enamino Ketones.

The Journal of organic chemistry

Fustero S, García De La Torre M, Pina B, Fuentes AS.
PMID: 11674620
J Org Chem. 1999 Jul 23;64(15):5551-5556. doi: 10.1021/jo990392w.

Reaction of fluorinated imidoyl chlorides 3 with ketimines 1a provides fluorinated 1,3-diimines, which were exclusively isolated as vinylogous amidine tautomers 2beta, with good yields. Fluorinated beta-enamino ketones 4 are obtained by regioselective hydrolysis of 2. Complementary methods for the...

Microwave-assisted extraction through an aqueous medium and simultaneous cleanup by partition on hexane for determining pesticides in agricultural soils by gas chromatography: a critical study.

Analytica chimica acta

Fuentes E, Báez ME, Reyes D.
PMID: 17723703
Anal Chim Acta. 2006 Sep 25;578(2):122-30. doi: 10.1016/j.aca.2006.07.007. Epub 2006 Jul 08.

A simple microwave-assisted extraction and partitioning method (MAEP) using water-acetonitrile and n-hexane for desorption and simultaneous partitioning, respectively, together with gas chromatography (GC) was studied to determine representative pesticides (trifluralin, metolachlor, chlorpyriphos and triadimefon) with a broad range of...

Spinal cord toxoplasmosis as an unusual presentation of AIDS: case report and review of the literature.

International journal of emergency medicine

Garcia-Gubern C, Fuentes CR, Colon-Rolon L, Masvidal D.
PMID: 21373318
Int J Emerg Med. 2010 Sep 07;3(4):439-42. doi: 10.1007/s12245-010-0207-7.

Approximately 10% of patients with AIDS present with some neurological deficit as their initial complaint, and up to 80% will have CNS involvement during the course of their disease. Toxoplasmosis is the most common cause of cerebral mass lesions...

Negative correlation between bone mineral density and TSH receptor antibodies in long-term euthyroid postmenopausal women with treated Graves' disease.

Thyroid research

Ercolano MA, Drnovsek ML, Silva Croome MC, Moos M, Fuentes AM, Viale F, Feldt-Rasmussen U, Gauna AT.
PMID: 24020400
Thyroid Res. 2013 Sep 11;6(1):11. doi: 10.1186/1756-6614-6-11.

BACKGROUND: Thyrotoxicosis is a cause of secondary osteoporosis. High concentrations of triiodotironine (T3) in Graves' disease stimulate bone turnover, but it is unclear if euthyroidism will always normalize bone metabolism. Thyrotropin (TSH) is known to affect directly the bone...

Antioxidant and Antiplatelet Activities in Extracts from Green and Fully Ripe Tomato Fruits (Solanum lycopersicum) and Pomace from Industrial Tomato Processing.

Evidence-based complementary and alternative medicine : eCAM

Fuentes E, Carle R, Astudillo L, Guzmán L, Gutiérrez M, Carrasco G, Palomo I.
PMID: 23476707
Evid Based Complement Alternat Med. 2013;2013:867578. doi: 10.1155/2013/867578. Epub 2013 Feb 17.

The consumption of fruits and vegetables is accepted to be one of the strategies to reduce risk factors for these diseases. The aim of this study was to examine potential relationships between the antioxidant and the antiplatelet activities in...

Antiplatelet protocol: Effects of ingesting a tomato pomace extract on human platelet aggregation.

MethodsX

Concha-Meyer A, Fuentes E, Palomo I.
PMID: 31516846
MethodsX. 2019 Aug 24;6:1847-1853. doi: 10.1016/j.mex.2019.08.012. eCollection 2019.

Consumption of tomato and tomato-based products is associated with risk reduction of cardiovascular disease (CVD). Protective effect of tomato is not clearly understood, but there is an interest in its ability to affect platelet aggregation (coagulation). Therefore, the aim...

Showing 1 to 12 of 184 entries