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Showing 1 to 12 of 201 entries
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G proteins

diversity

Hepler JR.
GSID: 675F5vizT6EJ
JR Hepler, AG Gilman - Trends in biochemical sciences, 1992 - Elsevier

The family of heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins) serves an essential role in transducing receptor-generated signals across the plasma …

Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease.

The Journal of antimicrobial chemotherapy

Cornely OA, Robertson MN, Haider S, Grigg A, Geddes M, Aoun M, Heinz WJ, Raad I, Schanz U, Meyer RG, Hammond SP, Mullane KM, Ostermann H, Ullmann AJ, Zimmerli S, Van Iersel MLPS, Hepler DA, Waskin H, Kartsonis NA, Maertens J.
PMID: 29029280
J Antimicrob Chemother. 2017 Dec 01;72(12):3501. doi: 10.1093/jac/dkx382.

No abstract available.

Closing the blood pressure gap: an affordable proposal to save lives worldwide.

BMJ global health

Heller DJ, Kishore SP.
PMID: 29018587
BMJ Glob Health. 2017 Sep 25;2(3):e000429. doi: 10.1136/bmjgh-2017-000429. eCollection 2017.

No abstract available.

Localization of membrane-associated calcium following cytokinin treatment in Funaria using chlorotetracycline.

Planta

Saunders MJ, Hepler PK.
PMID: 24302427
Planta. 1981 Jul;152(3):272-81. doi: 10.1007/BF00385156.

We have investigated the changes in membrane-associated calcium that occur during cytokinin induced bud formation in Funaria hygrometrica Hedw. using the fluorescent Ca(2+)-chelate probe chlorotetracycline (CTC). In the target caulonema cells a localization of CTC fluorescent material becomes evident...

Is P-protein actin-like?-not yet.

Planta

Palevitz BA, Hepler PK.
PMID: 24435439
Planta. 1975 Jan;125(3):261-71. doi: 10.1007/BF00385602.

Microfilaments associated with cytoplasmic streaming in Nitella flexilis internodes can be decorated with heavy meromyosin (HMM) from rabbit, both in vitro in cytoplasmic suspensions, and in situ in glycerinated cell segments. The bound HMM consists of clearly discernible, polarized...

RGS14 regulates the lifetime of G.

Pharmacology research & perspectives

Brown NE, Lambert NA, Hepler JR.
PMID: 27713821
Pharmacol Res Perspect. 2016 Aug 18;4(5):e00249. doi: 10.1002/prp2.249. eCollection 2016 Oct.

RGS14 is a multifunctional scaffolding protein possessing two distinct G protein interaction sites including a regulator of G protein signaling (RGS) domain that acts as a GTPase activating protein (GAP) to deactivate G

Increases in Cytosolic Ca2+ in Parsley Mesophyll Cells Correlate with Leaf Senescence.

Plant physiology

Huang FY, Philosoph-Hadas S, Meir S, Callaham DA, Sabato R, Zelcer A, Hepler PK.
PMID: 12223791
Plant Physiol. 1997 Sep;115(1):51-60. doi: 10.1104/pp.115.1.51.

The ability to maintain the cytoplasmic Ca2+ concentration ([Ca2+]cyt) at homeostatic levels has been examined during leaf senescence in detached parsley (Petroselinum crispum) leaves. Fluorescence ratiometric imaging of mesophyll cells isolated from parsley leaves at various senescence stages and...

Precepts of medical education.

Marquette medical review

HELLER BI.
PMID: 13906227
Marquette Med Rev. 1962 Mar;27:134-6.

No abstract available.

Three-dimensional organization and dynamic changes of the actin cytoskeleton in embryo sacs of Zea mays and Torenia fournieri.

Protoplasma

Huang BQ, Fu Y, Zee SY, Hepler PK.
PMID: 18987799
Protoplasma. 1999;209(1):105-19. doi: 10.1007/BF01415706.

Actin organization was observed in m-maleimidobenzoic acid N-hydroxysuccinimide ester(MBS)-treated maize embryo sacs by confocal laser scanning microscopy. The results revealed that dynamic changes of actin occur not only in the degenerating synergid, but also in the egg during fertilization....

Direct birefringence measurements using moire ray deflection techniques.

Applied optics

Heller DF, Kafri O, Krasinski J.
PMID: 18223999
Appl Opt. 1985 Sep 15;24(18):3037. doi: 10.1364/ao.24.003037.

No abstract available.

Lymphoepithelioma-like carcinoma of the vulva.

Journal of lower genital tract disease

Niu W, Heller DS, D'Cruz C.
PMID: 17051066
J Low Genit Tract Dis. 2003 Jul;7(3):184-6. doi: 10.1097/00128360-200307000-00005.

Lymphoepithelioma is well known in the nasopharyngeal region. Although this neoplasm is well described in a variety of extranasal sites, where it is termed lymphoepithelioma-like carcinoma, this is only the second report of this neoplasm originating in the vulva...

Calcium ionophore a23187 stimulates cytokinin-like mitosis in funaria.

Science (New York, N.Y.)

Saunders MJ, Hepler PK.
PMID: 17747957
Science. 1982 Sep 03;217(4563):943-5. doi: 10.1126/science.217.4563.943.

The plant hormone cytokinin stimulates asymmetrical division in target cells of the protonema of the moss Funaria hygrometrica, leading to bud formation. The initial division can be induced in the absence of cytokinin by the calcium ionophore A23187 in...

Showing 1 to 12 of 201 entries