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Showing 1 to 12 of 407 entries
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Population pharmacokinetics of olprinone in healthy male volunteers.

Clinical pharmacology : advances and applications

Kunisawa T, Kasai H, Suda M, Yoshimura M, Sugawara A, Izumi Y, Iida T, Kurosawa A, Iwasaki H.
PMID: 24623995
Clin Pharmacol. 2014 Mar 04;6:43-50. doi: 10.2147/CPAA.S50626. eCollection 2014.

BACKGROUND: Olprinone decreases the cardiac preload and/or afterload because of its vasodilatory effect and increases myocardial contractility by inhibiting phosphodiesterase III.PURPOSE: The objective of this study was to characterize the population pharmacokinetics of olprinone after a single continuous infusion...

Avalanche-like fluidization of a non-Brownian particle gel.

Soft matter

Kurokawa A, Vidal V, Kurita K, Divoux T, Manneville S.
PMID: 26403168
Soft Matter. 2015 Dec 14;11(46):9026-37. doi: 10.1039/c5sm01259g. Epub 2015 Sep 25.

We report on the fluidization dynamics of an attractive gel composed of non-Brownian particles made of fused silica colloids. Extensive rheology coupled to ultrasonic velocimetry allows us to characterize the global stress response together with the local dynamics of...

High-throughput powder diffraction measurement system consisting of multiple MYTHEN detectors at beamline BL02B2 of SPring-8.

The Review of scientific instruments

Kawaguchi S, Takemoto M, Osaka K, Nishibori E, Moriyoshi C, Kubota Y, Kuroiwa Y, Sugimoto K.
PMID: 28863664
Rev Sci Instrum. 2017 Aug;88(8):085111. doi: 10.1063/1.4999454.

In this study, we developed a user-friendly automatic powder diffraction measurement system for Debye-Scherrer geometry using a capillary sample at beamline BL02B2 of SPring-8. The measurement system consists of six one-dimensional solid-state (MYTHEN) detectors, a compact auto-sampler, wide-range temperature...

Corrigendum to "A split G-quadruplex-based DNA nano-tweezers structure as a signal-transducing molecule for the homogeneous detection of specific nucleic acids" [Biosens. Bioelectron. 74 (2015) 222-226].

Biosensors & bioelectronics

Nakatsuka K, Shigeto H, Kuroda A, Funabashi H.
PMID: 28292558
Biosens Bioelectron. 2017 Aug 15;94:729. doi: 10.1016/j.bios.2017.03.019. Epub 2017 Mar 11.

No abstract available.

Synthesis and Structure-Activity Relationship Study of 1-Phenyl-1-(quinazolin-4-yl)ethanols as Anticancer Agents.

ACS medicinal chemistry letters

Kuroiwa K, Ishii H, Matsuno K, Asai A, Suzuki Y.
PMID: 25815147
ACS Med Chem Lett. 2015 Jan 10;6(3):287-91. doi: 10.1021/ml5004684. eCollection 2015 Mar 12.

A quinazoline derivative PVHD121 (1a) was shown to have strong antiproliferative activity against various tumor-derived cell lines, including A549 (lung), NCI-H460 (lung), HCT116 (colon), MCF7 (breast), PC3 (prostate), and HeLa (cervical) cells with IC50 values from 0.1 to 0.3...

Inactivation of Sonic Hedgehog Signaling and Polydactyly in Limbs of Hereditary Multiple Malformation, a Novel Type of .

Frontiers in cell and developmental biology

Matsubara Y, Nakano M, Kawamura K, Tsudzuki M, Funahashi JI, Agata K, Matsuda Y, Kuroiwa A, Suzuki T.
PMID: 28083533
Front Cell Dev Biol. 2016 Dec 27;4:149. doi: 10.3389/fcell.2016.00149. eCollection 2016.

Hereditary Multiple Malformation (HMM) is a naturally occurring, autosomal recessive, homozygous lethal mutation found in Japanese quail. Homozygote embryos (

A prospective, multicentre, single-arm clinical trial of bevacizumab for patients with surgically untreatable, symptomatic brain radiation necrosis.

Neuro-oncology practice

Furuse M, Nonoguchi N, Kuroiwa T, Miyamoto S, Arakawa Y, Shinoda J, Miwa K, Iuchi T, Tsuboi K, Houkin K, Terasaka S, Tabei Y, Nakamura H, Nagane M, Sugiyama K, Terasaki M, Abe T, Narita Y, Saito N, Mukasa A, Ogasawara K, Beppu T, Kumabe T, Nariai T, Tsuyuguchi N, Nakatani E, Kurisu S, Nakagawa Y, Miyatake SI.
PMID: 27833757
Neurooncol Pract. 2016 Dec;3(4):272-280. doi: 10.1093/nop/npv064. Epub 2016 Jan 07.

BACKGROUND: Brain radiation necrosis (BRN) can be a complication of radiotherapy for primary and secondary brain tumors, as well as head and neck tumors. Since vascular endothelial growth factor (VEGF) is also a vascular permeability factor in the brain,...

Analysis of oxygen vacancy in Co-doped ZnO using the electron density distribution obtained using MEM.

Nanoscale research letters

Park JH, Lee YJ, Bae JS, Kim BS, Cho YC, Moriyoshi C, Kuroiwa Y, Lee S, Jeong SY.
PMID: 25977658
Nanoscale Res Lett. 2015 Apr 18;10:186. doi: 10.1186/s11671-015-0887-2. eCollection 2015.

Oxygen vacancy (VO) strongly affects the properties of oxides. In this study, we used X-ray diffraction (XRD) to study changes in the VO concentration as a function of the Co-doping level of ZnO. Rietveld refinement yielded a different result...

Regular insulin, rather than rapid-acting insulin, is a suitable choice for premeal bolus insulin in lean patients with type 2 diabetes mellitus.

Journal of diabetes investigation

Kuroda A, Kaneto H, Kawashima S, Sakamoto K, Takahara M, Shiraiwa T, Yasuda T, Katakami N, Matsuoka TA, Shimomura I, Matsuhisa M.
PMID: 24843634
J Diabetes Investig. 2013 Jan 29;4(1):78-81. doi: 10.1111/j.2040-1124.2012.00231.x. Epub 2012 Aug 21.

The aim of the present study was to compare the usefulness of premeal rapid-acting and regular insulin in type 2 diabetes patients. A total of 56 type 2 diabetic patients were investigated during hospitalization. Premeal rapid-acting insulin was applied...

Cytological Features of a Variant NUT Midline Carcinoma of the Lung Harboring the NSD3-NUT Fusion Gene: A Case Report and Literature Review.

Case reports in pathology

Kuroda S, Suzuki S, Kurita A, Muraki M, Aoshima Y, Tanioka F, Sugimura H.
PMID: 25685583
Case Rep Pathol. 2015;2015:572951. doi: 10.1155/2015/572951. Epub 2015 Jan 19.

Background. Nuclear protein in testis (NUT) midline carcinoma (NMC) is a very rare and aggressive malignancy. In more than two-thirds of these NMC cases, a fusion between NUT and BRD4 or BRD3 has been documented; other variants are rare....

Development of a Reference Material for Image Sharpness Evaluation in Scanning Electron Microscopy - ERRATUM.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada

Kumagai K, Kurokawa A.
PMID: 27641940
Microsc Microanal. 2016 Sep 19;1. doi: 10.1017/S1431927616011703. Epub 2016 Sep 19.

No abstract available.

Left ventricular apical aneurysm due to unrecognized sarcoidosis.

Journal of echocardiography

Masuno T, Hirata K, Wada N, Endo H, Takemoto K, Nishiguchi T, Teraguchi I, Maniwa N, Shimokado A, Kashiwagi M, Tsujioka H, Ikejima H, Kuroi A, Ishibashi K, Komukai K, Tanimoto T, Ino Y, Kitabata H, Kimura K, Imanishi T, Akasaka T.
PMID: 27278945
J Echocardiogr. 2010 Dec;8(4):129-30. doi: 10.1007/s12574-010-0046-9. Epub 2010 Jun 04.

A 47-year-old woman was hospitalized for syncope. An electrocardiogram showed complete right bundle branch block and T-wave inversion in leads III, aVF, and V2-4. Cardiac catheterization was performed since the echocardiogram demonstrated the existence of a left ventricular apical...

Showing 1 to 12 of 407 entries