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Showing 1 to 12 of 251 entries
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Computer modeling defines the system driving a constant current crucial for homeostasis in the mammalian cochlea by integrating unique ion transports.

NPJ systems biology and applications

Nin F, Yoshida T, Murakami S, Ogata G, Uetsuka S, Choi S, Doi K, Sawamura S, Inohara H, Komune S, Kurachi Y, Hibino H.
PMID: 28861279
NPJ Syst Biol Appl. 2017 Aug 25;3:24. doi: 10.1038/s41540-017-0025-0. eCollection 2017.

The cochlear lateral wall-an epithelial-like tissue comprising inner and outer layers-maintains +80 mV in endolymph. This endocochlear potential supports hearing and represents the sum of all membrane potentials across apical and basolateral surfaces of both layers. The apical surfaces...

Novel OPN1LW/OPN1MW deletion mutations in 2 Japanese families with blue cone monochromacy.

Human genome variation

Wang C, Hosono K, Kachi S, Suto K, Nakamura M, Terasaki H, Miyake Y, Hotta Y, Minoshima S.
PMID: 27274860
Hum Genome Var. 2016 May 26;3:16011. doi: 10.1038/hgv.2016.11. eCollection 2016.

Blue cone monochromacy (BCM) is caused by the lack of expression of the normal proteins encoded by the OPN1LW and OPN1MW genes, resulting in the absence of red and green cone sensitivities. We analyzed two cases of BCM in...

Possible influences of exercise-intensity-dependent increases in non-cortical hemodynamic variables on NIRS-based neuroimaging analysis during cognitive tasks: Technical note.

Journal of exercise nutrition & biochemistry

Byun K, Hyodo K, Suwabe K, Kujach S, Kato M, Soya H.
PMID: 25671198
J Exerc Nutrition Biochem. 2014 Dec;18(4):327-32. doi: 10.5717/jenb.2014.18.4.327. Epub 2014 Nov 27.

PURPOSE: Functional near-infrared spectroscopy (fNIRS) provides functional imaging of cortical activations by measuring regional oxy- and deoxy-hemoglobin (Hb) changes in the forehead during a cognitive task. There are, however, potential problems regarding NIRS signal contamination by non-cortical hemodynamic (NCH)...

Synergistic effect of α-glucosidase inhibitors and dipeptidyl peptidase 4 inhibitor treatment.

Journal of diabetes investigation

Horikawa Y, Enya M, Iizuka K, Chen GY, Kawachi S, Suwa T, Takeda J.
PMID: 24843484
J Diabetes Investig. 2011 Jun 05;2(3):200-3. doi: 10.1111/j.2040-1124.2010.00081.x.

Monotherapy of α-glucosidase inhibitor (α-GI) or dipeptidyl peptidase 4 (DPP4) inhibitor does not sufficiently minimize glucose fluctuations in the diabetic state. In the present study, we evaluated the combined effects of various of α-GI inhibitors (acarbose, voglibose or miglitol)...

Steroid minimization immunosuppression protocol using basiliximab in adult living donor liver transplantation for hepatitis C virus-related cirrhosis.

Hepatology research : the official journal of the Japan Society of Hepatology

Hibi T, Shinoda M, Itano O, Obara H, Kitago M, Abe Y, Yagi H, Tanaka M, Hoshino K, Fujino A, Kuroda T, Kawachi S, Tanabe M, Shimazu M, Kitagawa Y.
PMID: 25594837
Hepatol Res. 2015 Dec;45(12):1178-84. doi: 10.1111/hepr.12486. Epub 2015 Feb 26.

AIM: Recent randomized trials have failed to prove the benefit of steroid-free immunosuppression in liver transplantation for hepatitis C virus (HCV)-related cirrhosis. Furthermore, there is a lack of data on the use of basiliximab in living donor liver transplantation...

BK polyoma virus infection and renal disease in non-renal solid organ transplantation.

Clinical kidney journal

Kuppachi S, Kaur D, Holanda DG, Thomas CP.
PMID: 26985385
Clin Kidney J. 2016 Apr;9(2):310-8. doi: 10.1093/ckj/sfv143. Epub 2015 Dec 30.

BK virus (BKV) is a non-enveloped DNA virus of the polyomaviridae family that causes an interstitial nephritis in immunosuppressed patients. BKV nephropathy is now a leading cause of chronic kidney disease and early allograft failure following kidney transplantation. It...

Bouveret's syndrome with a concomitant incidental T1 gallbladder cancer.

Clinical journal of gastroenterology

Shinoda M, Aiura K, Yamagishi Y, Masugi Y, Takano K, Maruyama S, Irino T, Takabayashi K, Hoshino Y, Nishiya S, Hibi T, Kawachi S, Tanabe M, Ueda M, Sakamoto M, Hibi T, Kitagawa Y.
PMID: 26190330
Clin J Gastroenterol. 2010 Oct;3(5):248-53. doi: 10.1007/s12328-010-0170-0. Epub 2010 Sep 04.

Bouveret's syndrome, which is a gastric outlet obstruction caused by a gallstone in the duodenum, is a rare complication of gallstone disease. We report a case of Bouveret's syndrome in an 81-year-old woman who also exhibited incidental gallbladder cancer....

A simple test for the cleavage activity of customized endonucleases in plants.

Plant methods

Budhagatapalli N, Schedel S, Gurushidze M, Pencs S, Hiekel S, Rutten T, Kusch S, Morbitzer R, Lahaye T, Panstruga R, Kumlehn J, Hensel G.
PMID: 26962325
Plant Methods. 2016 Mar 09;12:18. doi: 10.1186/s13007-016-0118-6. eCollection 2016.

BACKGROUND: Although customized endonucleases [transcription activator-like effector nucleases (TALENs) and RNA-guided endonucleases (RGENs)] are known to be effective agents of mutagenesis in various host plants, newly designed endonuclease constructs require some pre-validation with respect to functionality before investing in...

T-817MA, but Not Haloperidol and Risperidone, Restores Parvalbumin-Positive γ -Aminobutyric Acid Neurons in the Prefrontal Cortex and Hippocampus of Rats Transiently Exposed to MK-801 at the Neonatal Period.

ISRN psychiatry

Uehara T, Sumiyoshi T, Seo T, Matsuoka T, Itoh H, Kurachi M.
PMID: 23738215
ISRN Psychiatry. 2012 Jul 08;2012:947149. doi: 10.5402/2012/947149. Print 2012.

The number of parvalbumin (PV)-positive γ -aminobutyric acid (GABA) neurons is decreased in the brain of rats transiently exposed to MK-801, an N-methyl-D-aspartate (NMDA) receptor blocker, in the neonatal stage (Uehara et al. (2012)). T-817MA [1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl} azetidin-3-ol maleate] is...

[Symposium. Nursing and nursing education].

[Kango kyoiku] Japanese journal of nurses' education

Usui T, Imamura E, Kachi S, Goto M, Nagate M.
PMID: 5211637
Kango Kyoiku. 1971 Nov;12(11):1-15.

No abstract available.

[For the preparation for psychiatric specialist training programs: from a viewpoint of university hospitals].

Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica

Kurachi M, Sumida M, Takahashi T.
PMID: 17137196
Seishin Shinkeigaku Zasshi. 2006;108(9):925-30.

No abstract available.

Exclusive anti-Stokes Raman scattering using coherent material excitation.

Optics letters

Wada S, Kurachi M, Arasaki T, Kasai A, Tashiro H.
PMID: 19777038
Opt Lett. 1991 Oct 15;16(20):1581-3. doi: 10.1364/ol.16.001581.

A new process capable of scattering intense anti-Stokes waves that uses stimulated electronic Raman scattering in metal vapor is proposed. The coherent material excitation produced by a prepump pulse couples with the forthcoming main pulse exclusively to create polarization...

Showing 1 to 12 of 251 entries