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Showing 1 to 5 of 5 entries
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Delaying Effects of Prolactin and Growth Hormone on Aging Processes in Bovine Oocytes Matured In Vitro.

Pharmaceuticals (Basel, Switzerland)

Singina GN, Shedova EN, Lopukhov AV, Mityashova OS, Lebedeva IY.
PMID: 34358110
Pharmaceuticals (Basel). 2021 Jul 16;14(7). doi: 10.3390/ph14070684.

Aging processes accelerate dramatically in oocytes that have reached the metaphase-II (M-II) stage. The present work aimed to study the patterns and intracellular pathways of actions of prolactin (PRL) and growth hormone (GH) on age-associated changes in bovine M-II...

Evaluation of multiple reaction monitoring cubed performed by a quadrupole-linear ion trap mass spectrometer for quantitative determination of 6-sulfatoxymelatonin in urine.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Lopukhov LV, Balandina AV, Nigmatullina LS, Mullakhmetova AF, Synbulatova GE, Laikov AV, Lopukhov VL, Grigoryeva TV.
PMID: 35030474
J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Jan 10;1190:123094. doi: 10.1016/j.jchromb.2021.123094. Epub 2022 Jan 10.

Liquid chromatography (LC) - mass spectrometry quantitative analysis of substances in biological samples is usually performed in the multiple reaction monitoring (MRM) variant. In complex biological matrices, strong interferences can be observed when using the LC-MRM method. Interference levels...

Mannosylated Cationic Copolymers for Gene Delivery to Macrophages.

Macromolecular bioscience

Lopukhov AV, Yang Z, Haney MJ, Bronich TK, Sokolsky-Papkov M, Batrakova EV, Klyachko NL, Kabanov AV.
PMID: 33615675
Macromol Biosci. 2021 Apr;21(4):e2000371. doi: 10.1002/mabi.202000371. Epub 2021 Feb 22.

Macrophages are desirable targets for gene therapy of cancer and other diseases. Cationic diblock copolymers of polyethylene glycol (PEG) and poly-L-lysine (PLL) or poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (pAsp(DET)) are synthesized and used to form polyplexes with a plasmid DNA (pDNA) that are...

Prolactin and growth hormone affect metaphase-II chromosomes in aging oocytes via cumulus cells using similar signaling pathways.

Frontiers in genetics

Lebedeva IY, Singina GN, Lopukhov AV, Shedova EN, Zinovieva NA.
PMID: 26379702
Front Genet. 2015 Aug 27;6:274. doi: 10.3389/fgene.2015.00274. eCollection 2015.

General senescence of the adult organism is closely connected with reproductive one. Meanwhile, the age-related reduction in the female fertility is primarily associated with a decline in the gamete quality. Molecular and cellular changes in oocytes of old mammalian...

Evaluation of multiple reaction monitoring cubed performed by a quadrupole-linear ion trap mass spectrometer for quantitative determination of 6-sulfatoxymelatonin in urine.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Lopukhov LV, Balandina AV, Nigmatullina LS, Mullakhmetova AF, Synbulatova GE, Laikov AV, Lopukhov VL, Grigoryeva TV.
PMID: 35030474
J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Jan 10;1190:123094. doi: 10.1016/j.jchromb.2021.123094. Epub 2022 Jan 10.

Liquid chromatography (LC) - mass spectrometry quantitative analysis of substances in biological samples is usually performed in the multiple reaction monitoring (MRM) variant. In complex biological matrices, strong interferences can be observed when using the LC-MRM method. Interference levels...

Showing 1 to 5 of 5 entries