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Showing 1 to 12 of 65 entries
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Ethanol-induced steatosis involves impairment of lipophagy, associated with reduced Dynamin2 activity.

Hepatology communications

Rasineni K, Donohue TM, Thomes PG, Yang L, Tuma DJ, McNiven MA, Casey CA.
PMID: 29152606
Hepatol Commun. 2017 Aug;1(6):501-512. doi: 10.1002/hep4.1063. Epub 2017 Jul 10.

BACKGROUND: Lipid droplets (LDs), the organelles central to alcoholic steatosis, are broken down by lipophagy, a specialized form of autophagy. Here, we hypothesize that ethanol administration retards lipophagy by down-regulating Dynamin 2 (Dyn2), a protein that facilitates lysosome re-formation,...

Comparison of different extenders for the cryopreservation of Atlantic salmon spermatozoa.

Theriogenology

Gallant RK, Richardson GF, McNiven MA.
PMID: 16727331
Theriogenology. 1993 Sep;40(3):479-86. doi: 10.1016/0093-691x(93)90401-p.

Fifteen extenders were produced by adding dimethyl sulfoxide (DMSO) at 8, 10 or 12% of diluent volume to 5 diluents. All extenders were cooled to 4 degrees C. Pooled Atlantic salmon (Salmo salar) semen with greater than 90% progressive...

Dimethyl-acetamide as a cryoprotectant for rainbow trout spermatozoa.

Theriogenology

McNiven MA, Gallant RK, Richardson GF.
PMID: 16727376
Theriogenology. 1993 Nov;40(5):943-8. doi: 10.1016/0093-691x(93)90362-9.

Dimethyl-acetamide was evaluated as a cryoprotectant for rainbow trout (Oncorhynchus mykiss ) semen on the basis of motility, percentage of dead spermatozoa as determined by fluorometry, and fertility of frozen-thawed spermatozoa. Dimethyl-acetamide performed significantly better (P

In vitro methods of assessing the viability of rainbow trout spermatozoa.

Theriogenology

McNiven MA, Gallant RK, Richardson GF.
PMID: 16727170
Theriogenology. 1992 Oct;38(4):679-86. doi: 10.1016/0093-691x(92)90030-u.

The accuracy of three in vitro methods for estimating the proportion of dead rainbow trout (Onchorhynchus mykiss) spermatozoa was investigated. Motility rating, fluorometry using ethidium bromide, and lactate dehydrogenase (LDH) activity in seminal plasma were compared. Semen samples were...

MODIFICATION OF THE STRUCTURE OF WATER IN AGAR GELS.

Proceedings of the National Academy of Sciences of the United States of America

Hechter O, Wittstruck T, McNiven N, Lester G.
PMID: 16590671
Proc Natl Acad Sci U S A. 1960 Jun;46(6):783-7. doi: 10.1073/pnas.46.6.783.

No abstract available.

FURTHER STUDIES ON INCREASED SUSCEPTIBILITY TO CHLOROFORM POISONING PRODUCED IN THE ALBINO RAT BY INJECTION OF CRYSTALLINE THYROXIN.

The Journal of clinical investigation

McIver MA, Winter EA.
PMID: 16694902
J Clin Invest. 1942 Mar;21(2):191-6. doi: 10.1172/JCI101290.

No abstract available.

Optical detection of chloramphenicol using molecularly imprinted polymers.

Analytical chemistry

Levi R, McNiven S, Piletsky SA, Cheong SH, Yano K, Karube I.
PMID: 21639240
Anal Chem. 1997 Jun 01;69(11):2017-21. doi: 10.1021/ac960983b.

A practical optical sensing system for the determination of chloramphenicol (CAP), utilizing molecularly imprinted polymers (MIPs) and HPLC, has been developed. The method is based on competitive displacement of a chloramphenicol-methyl red (CAP-MR) dye conjugate from specific binding cavities...

THE ACID-BASE COMPOSITION OF GASTRIC SECRETIONS.

The Journal of experimental medicine

Gamble JL, McIver MA.
PMID: 19869525
J Exp Med. 1928 Nov 30;48(6):837-47. doi: 10.1084/jem.48.6.837.

The chief inorganic factors in secretions obtained from isolated pouches constructed in the fundus and in the pyloric antrum of the cat's stomach were found to be chloride ion and fixed base. In a series of samples obtained from...

Hepatic Lipophagy: New Insights into Autophagic Catabolism of Lipid Droplets in the Liver.

Hepatology communications

Schulze RJ, Drižytė K, Casey CA, McNiven MA.
PMID: 29109982
Hepatol Commun. 2017 Jul;1(5):359-369. doi: 10.1002/hep4.1056. Epub 2017 Jun 09.

The liver is a central fat-storage organ, making it especially susceptible to steatosis as well as subsequent inflammation and cirrhosis. The mechanisms by which the liver mobilizes stored lipid for energy production, however, remain incompletely defined. The catabolic process...

Atypical Rett Syndrome and Intractable Epilepsy With Novel .

Child neurology open

Kyriakopoulos P, McNiven V, Carter MT, Humphreys P, Dyment D, Fantaneanu TA.
PMID: 30151416
Child Neurol Open. 2018 Aug 23;5:2329048X18787946. doi: 10.1177/2329048X18787946. eCollection 2018.

No abstract available.

New cases that expand the genotypic and phenotypic spectrum of Congenital NAD Deficiency Disorder.

Human mutation

Szot JO, Slavotinek A, Chong K, Brandau O, Nezarati M, Cueto-González AM, Patel MS, Devine WP, Rego S, Acyinena AP, Shannon P, Myles-Reid D, Blaser S, Mieghem TV, Yavuz-Kienle H, Skladny H, Miller K, Riera MDT, Martínez SA, Tizzano EF, Dupuis L, James Stavropoulos D, McNiven V, Mendoza-Londono R, Elliott AM, Phillips RS, Chapman G, Dunwoodie SL.
PMID: 33942433
Hum Mutat. 2021 Jul;42(7):862-876. doi: 10.1002/humu.24211. Epub 2021 May 16.

Nicotinamide adenine dinucleotide (NAD) is an essential coenzyme involved in over 400 cellular reactions. During embryogenesis, mammals synthesize NAD de novo from dietary l -tryptophan via the kynurenine pathway. Biallelic, inactivating variants in three genes encoding enzymes of this...

Ménière's disease: management in primary care.

The British journal of general practice : the journal of the Royal College of General Practitioners

McNiven ND, Deutsch PG, Carlin JE, Trotter MI.
PMID: 34824080
Br J Gen Pract. 2021 Nov 25;71(713):571-572. doi: 10.3399/bjgp21X717989. Print 2021 Dec.

No abstract available.

Showing 1 to 12 of 65 entries