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Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome.

PloS one

Powell NM, Modat M, Cardoso MJ, Ma D, Holmes HE, Yu Y, O'Callaghan J, Cleary JO, Sinclair B, Wiseman FK, Tybulewicz VL, Fisher EM, Lythgoe MF, Ourselin S.
PMID: 27658297
PLoS One. 2016 Sep 22;11(9):e0162974. doi: 10.1371/journal.pone.0162974. eCollection 2016.

We describe a fully automated pipeline for the morphometric phenotyping of mouse brains from μMRI data, and show its application to the Tc1 mouse model of Down syndrome, to identify new morphological phenotypes in the brain of this first...

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Powell NM, Modat M, Cardoso MJ, et al. Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome. PLoS One. 2016;11(9):e0162974doi: 10.1371/journal.pone.0162974.
Powell, N. M., Modat, M., Cardoso, M. J., Ma, D., Holmes, H. E., Yu, Y., O'Callaghan, J., Cleary, J. O., Sinclair, B., Wiseman, F. K., Tybulewicz, V. L., Fisher, E. M., Lythgoe, M. F., & Ourselin, S. (2016). Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome. PloS one, 11(9), e0162974. https://doi.org/10.1371/journal.pone.0162974
Powell, Nick M, et al. "Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome." PloS one vol. 11,9 (2016): e0162974. doi: https://doi.org/10.1371/journal.pone.0162974
Powell NM, Modat M, Cardoso MJ, Ma D, Holmes HE, Yu Y, O'Callaghan J, Cleary JO, Sinclair B, Wiseman FK, Tybulewicz VL, Fisher EM, Lythgoe MF, Ourselin S. Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome. PLoS One. 2016 Sep 22;11(9):e0162974. doi: 10.1371/journal.pone.0162974. eCollection 2016. PMID: 27658297; PMCID: PMC5033246.
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heatmaply: an R package for creating interactive cluster heatmaps for online publishing.

Bioinformatics (Oxford, England)

Galili T, O'Callaghan A, Sidi J, Sievert C.
PMID: 29069305
Bioinformatics. 2018 May 01;34(9):1600-1602. doi: 10.1093/bioinformatics/btx657.

SUMMARY: heatmaply is an R package for easily creating interactive cluster heatmaps that can be shared online as a stand-alone HTML file. Interactivity includes a tooltip display of values when hovering over cells, as well as the ability to...

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Galili T, O'Callaghan A, Sidi J, et al. heatmaply: an R package for creating interactive cluster heatmaps for online publishing. Bioinformatics. 2018;34(9):1600-1602doi: 10.1093/bioinformatics/btx657.
Galili, T., O'Callaghan, A., Sidi, J., & Sievert, C. (2018). heatmaply: an R package for creating interactive cluster heatmaps for online publishing. Bioinformatics (Oxford, England), 34(9), 1600-1602. https://doi.org/10.1093/bioinformatics/btx657
Galili, Tal, et al. "heatmaply: an R package for creating interactive cluster heatmaps for online publishing." Bioinformatics (Oxford, England) vol. 34,9 (2018): 1600-1602. doi: https://doi.org/10.1093/bioinformatics/btx657
Galili T, O'Callaghan A, Sidi J, Sievert C. heatmaply: an R package for creating interactive cluster heatmaps for online publishing. Bioinformatics. 2018 May 01;34(9):1600-1602. doi: 10.1093/bioinformatics/btx657. PMID: 29069305; PMCID: PMC5925766.
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First demonstration of a 2μm few-mode TDFA for mode division multiplexing.

Optics express

Jung Y, Shardlow PC, Belal M, Li Z, Heidt AM, Daniel JM, Jain D, Sahu JK, Clarkson WA, Corbett B, O'Callaghan J, Alam SU, Richardson DJ.
PMID: 24921756
Opt Express. 2014 May 05;22(9):10544-9. doi: 10.1364/OE.22.010544.

We report the first demonstration of an inline few-mode thulium doped fiber amplifier (TDFA) operating at 2μm for mode division multiplexed transmission. Similar gain and noise figure performance for both the LP(01) and LP(11) modes are obtained in a...

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Jung Y, Shardlow PC, Belal M, et al. First demonstration of a 2μm few-mode TDFA for mode division multiplexing. Opt Express. 2014;22(9):10544-9doi: 10.1364/OE.22.010544.
Jung, Y., Shardlow, P. C., Belal, M., Li, Z., Heidt, A. M., Daniel, J. M., Jain, D., Sahu, J. K., Clarkson, W. A., Corbett, B., O'Callaghan, J., Alam, S. U., & Richardson, D. J. (2014). First demonstration of a 2μm few-mode TDFA for mode division multiplexing. Optics express, 22(9), 10544-9. https://doi.org/10.1364/OE.22.010544
Jung, Y, et al. "First demonstration of a 2μm few-mode TDFA for mode division multiplexing." Optics express vol. 22,9 (2014): 10544-9. doi: https://doi.org/10.1364/OE.22.010544
Jung Y, Shardlow PC, Belal M, Li Z, Heidt AM, Daniel JM, Jain D, Sahu JK, Clarkson WA, Corbett B, O'Callaghan J, Alam SU, Richardson DJ. First demonstration of a 2μm few-mode TDFA for mode division multiplexing. Opt Express. 2014 May 05;22(9):10544-9. doi: 10.1364/OE.22.010544. PMID: 24921756.
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10 Gb/s InP-based Mach-Zehnder modulator for operation at 2 μm wavelengths.

Optics express

Sadiq MU, Gleeson MR, Ye N, O'Callaghan J, Morrissey P, Zhang HY, Thomas K, Gocalinska A, Pelucchi E, Gunning FC, Roycroft B, Peters FH, Corbett B.
PMID: 25969186
Opt Express. 2015 May 04;23(9):10905-13. doi: 10.1364/OE.23.010905.

We report on the first InP-based Mach-Zehnder modulator (MZM) employing quantum-confined Stark effect (QCSE) for operation around 2000 nm. The polarization sensitive device is based on 15 compressively strained quantum wells and achieves an electro-optic (EO) bandwidth of at...

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Sadiq MU, Gleeson MR, Ye N, et al. 10 Gb/s InP-based Mach-Zehnder modulator for operation at 2 μm wavelengths. Opt Express. 2015;23(9):10905-13doi: 10.1364/OE.23.010905.
Sadiq, M. U., Gleeson, M. R., Ye, N., O'Callaghan, J., Morrissey, P., Zhang, H. Y., Thomas, K., Gocalinska, A., Pelucchi, E., Gunning, F. C., Roycroft, B., Peters, F. H., & Corbett, B. (2015). 10 Gb/s InP-based Mach-Zehnder modulator for operation at 2 μm wavelengths. Optics express, 23(9), 10905-13. https://doi.org/10.1364/OE.23.010905
Sadiq, M U, et al. "10 Gb/s InP-based Mach-Zehnder modulator for operation at 2 μm wavelengths." Optics express vol. 23,9 (2015): 10905-13. doi: https://doi.org/10.1364/OE.23.010905
Sadiq MU, Gleeson MR, Ye N, O'Callaghan J, Morrissey P, Zhang HY, Thomas K, Gocalinska A, Pelucchi E, Gunning FC, Roycroft B, Peters FH, Corbett B. 10 Gb/s InP-based Mach-Zehnder modulator for operation at 2 μm wavelengths. Opt Express. 2015 May 04;23(9):10905-13. doi: 10.1364/OE.23.010905. PMID: 25969186.
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Hypermethylation of MAPK13 Promoter in Oesophageal Squamous Cell Carcinoma Is Associated with Loss of p38δ MAPK Expression.

Cancers

O' Callaghan C, Fanning LJ, Barry OP.
PMID: 26512696
Cancers (Basel). 2015 Oct 23;7(4):2124-33. doi: 10.3390/cancers7040881.

The loss of tumour suppressor gene function is a hallmark of malignant transformation and can occur by a variety of genetic and/or epigenetic alterations. We have previously characterised p38δ mitogen-activated protein kinase (MAPK) as a tumour suppressor in oesophageal...

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O' Callaghan C, Fanning LJ, Barry OP. Hypermethylation of MAPK13 Promoter in Oesophageal Squamous Cell Carcinoma Is Associated with Loss of p38δ MAPK Expression. Cancers (Basel). 2015;7(4):2124-33doi: 10.3390/cancers7040881.
O' Callaghan, C., Fanning, L. J., & Barry, O. P. (2015). Hypermethylation of MAPK13 Promoter in Oesophageal Squamous Cell Carcinoma Is Associated with Loss of p38δ MAPK Expression. Cancers, 7(4), 2124-33. https://doi.org/10.3390/cancers7040881
O' Callaghan, Carol, et al. "Hypermethylation of MAPK13 Promoter in Oesophageal Squamous Cell Carcinoma Is Associated with Loss of p38δ MAPK Expression." Cancers vol. 7,4 (2015): 2124-33. doi: https://doi.org/10.3390/cancers7040881
O' Callaghan C, Fanning LJ, Barry OP. Hypermethylation of MAPK13 Promoter in Oesophageal Squamous Cell Carcinoma Is Associated with Loss of p38δ MAPK Expression. Cancers (Basel). 2015 Oct 23;7(4):2124-33. doi: 10.3390/cancers7040881. PMID: 26512696; PMCID: PMC4695881.
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Switching dynamics and surface forces in thresholdless "V-shaped" switching ferroelectric liquid crystals.

Physical review. E, Statistical, nonlinear, and soft matter physics

O'Callaghan MJ.
PMID: 12636520
Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Jan;67(1):011710. doi: 10.1103/PhysRevE.67.011710. Epub 2003 Jan 31.

The electrostatic model of thresholdless V-shaped switching is able to explain the general low frequency (quasistatic) electro-optic behavior of smectic-C* ferroelectric liquid crystals (vFLCs). Here, dynamical equations based on the electrostatic model are developed which predict a vFLC cell's...

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O'Callaghan MJ. Switching dynamics and surface forces in thresholdless "V-shaped" switching ferroelectric liquid crystals. Phys Rev E Stat Nonlin Soft Matter Phys. 2003;67(1):011710doi: 10.1103/PhysRevE.67.011710.
O'Callaghan, M. J. (2003). Switching dynamics and surface forces in thresholdless "V-shaped" switching ferroelectric liquid crystals. Physical review. E, Statistical, nonlinear, and soft matter physics, 67(1), 011710. https://doi.org/10.1103/PhysRevE.67.011710
O'Callaghan, Michael J. "Switching dynamics and surface forces in thresholdless "V-shaped" switching ferroelectric liquid crystals." Physical review. E, Statistical, nonlinear, and soft matter physics vol. 67,1 (2003): 011710. doi: https://doi.org/10.1103/PhysRevE.67.011710
O'Callaghan MJ. Switching dynamics and surface forces in thresholdless "V-shaped" switching ferroelectric liquid crystals. Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Jan;67(1):011710. doi: 10.1103/PhysRevE.67.011710. Epub 2003 Jan 31. PMID: 12636520.
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von Willebrand Factor in CHD and stroke: relationships and therapeutic implications.

Current treatment options in cardiovascular medicine

Cooney MT, Dudina AL, O'Callaghan P, Graham IM.
PMID: 17601381
Curr Treat Options Cardiovasc Med. 2007 Jun;9(3):180-90. doi: 10.1007/s11936-007-0011-8.

Atherosclerotic cardiovascular disease (CVD), which includes coronary heart disease (CHD) and stroke, is now the most common cause of death in the middle aged and elderly in all parts of the world except subSaharan Africa. The direct cause of...

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Cooney MT, Dudina AL, O'Callaghan P, et al. von Willebrand Factor in CHD and stroke: relationships and therapeutic implications. Curr Treat Options Cardiovasc Med. 2007;9(3):180-90doi: 10.1007/s11936-007-0011-8.
Cooney, M. T., Dudina, A. L., O'Callaghan, P., & Graham, I. M. (2007). von Willebrand Factor in CHD and stroke: relationships and therapeutic implications. Current treatment options in cardiovascular medicine, 9(3), 180-90. https://doi.org/10.1007/s11936-007-0011-8
Cooney, Marie-Therese, et al. "von Willebrand Factor in CHD and stroke: relationships and therapeutic implications." Current treatment options in cardiovascular medicine vol. 9,3 (2007): 180-90. doi: https://doi.org/10.1007/s11936-007-0011-8
Cooney MT, Dudina AL, O'Callaghan P, Graham IM. von Willebrand Factor in CHD and stroke: relationships and therapeutic implications. Curr Treat Options Cardiovasc Med. 2007 Jun;9(3):180-90. doi: 10.1007/s11936-007-0011-8. PMID: 17601381.
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Targeting drug delivery to the lungs by inhalation.

Mediators of inflammation

O'Callaghan C.
PMID: 18475601
Mediators Inflamm. 1994;3(7):S31-3. doi: 10.1155/S0962935194000724.

Most drugs targeted to the respiratory tract are used for their local action. For example, ephidrine for nasal decongestion, beta-2 agonists for bronchodilatation, and inhaled steroids to suppress the inflammation seen in asthmatic airways. Since the drug is delivered...

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O'Callaghan C. Targeting drug delivery to the lungs by inhalation. Mediators Inflamm. 1994;3(7):S31-3doi: 10.1155/S0962935194000724.
O'Callaghan, C. (1994). Targeting drug delivery to the lungs by inhalation. Mediators of inflammation, 3(7), S31-3. https://doi.org/10.1155/S0962935194000724
O'Callaghan, C. "Targeting drug delivery to the lungs by inhalation." Mediators of inflammation vol. 3,7 (1994): S31-3. doi: https://doi.org/10.1155/S0962935194000724
O'Callaghan C. Targeting drug delivery to the lungs by inhalation. Mediators Inflamm. 1994;3(7):S31-3. doi: 10.1155/S0962935194000724. PMID: 18475601; PMCID: PMC2365599.
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Effect of rumen degradable bolus containing melatonin or progestagen pessary plus pregnant mare serum gonadotropin on estrus response and lambing rate in ewes.

Theriogenology

Crosby TF, O'callaghan D.
PMID: 16726943
Theriogenology. 1991 Apr;35(4):747-52. doi: 10.1016/0093-691x(91)90415-a.

Two practical regimens designed to induce estrus and ovulation in ewes in late anestrus were compared. Forty ewes were given a soluble glass rumen bolus containing 150 mg melatonin on July 9 and were joined with two vasectomized rams...

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Crosby TF, O'callaghan D. Effect of rumen degradable bolus containing melatonin or progestagen pessary plus pregnant mare serum gonadotropin on estrus response and lambing rate in ewes. Theriogenology. 1991;35(4):747-52doi: 10.1016/0093-691x(91)90415-a.
Crosby, T. F., & O'callaghan, D. (1991). Effect of rumen degradable bolus containing melatonin or progestagen pessary plus pregnant mare serum gonadotropin on estrus response and lambing rate in ewes. Theriogenology, 35(4), 747-52. https://doi.org/10.1016/0093-691x(91)90415-a
Crosby, T F, and O'callaghan, D. "Effect of rumen degradable bolus containing melatonin or progestagen pessary plus pregnant mare serum gonadotropin on estrus response and lambing rate in ewes." Theriogenology vol. 35,4 (1991): 747-52. doi: https://doi.org/10.1016/0093-691x(91)90415-a
Crosby TF, O'callaghan D. Effect of rumen degradable bolus containing melatonin or progestagen pessary plus pregnant mare serum gonadotropin on estrus response and lambing rate in ewes. Theriogenology. 1991 Apr;35(4):747-52. doi: 10.1016/0093-691x(91)90415-a. PMID: 16726943.
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MDMA toxicity presenting with severe hyperpyrexia: a case report.

Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

Connolly E, O'Callaghan G.
PMID: 16599881
Crit Care Resusc. 1999 Dec;1(4):368-70.

Ingestion of even small amounts of MDMA ('ecstasy') by a small subset of the population may result in a potentially fatal clinical syndrome of severe hyperpyrexia, cardiovascular collapse, coagulopathy, rhabdomyolysis and multiple organ failure. Rapid and aggressive temperature control...

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Connolly E, O'Callaghan G. MDMA toxicity presenting with severe hyperpyrexia: a case report. Crit Care Resusc. 1999;1(4):368-70
Connolly, E., & O'Callaghan, G. (1999). MDMA toxicity presenting with severe hyperpyrexia: a case report. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 1(4), 368-70.
Connolly, E, and O'Callaghan, G. "MDMA toxicity presenting with severe hyperpyrexia: a case report." Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine vol. 1,4 (1999): 368-70.
Connolly E, O'Callaghan G. MDMA toxicity presenting with severe hyperpyrexia: a case report. Crit Care Resusc. 1999 Dec;1(4):368-70. PMID: 16599881.
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Serial transform optical correlator design principles.

Applied optics

O'Callaghan MJ, Perlmutter SH.
PMID: 18360354
Appl Opt. 2001 Jul 10;40(20):3311-7. doi: 10.1364/ao.40.003311.

Optical correlators such as the 4f and VanderLugt optical systems have been an active area of research for many years; we refer to these types of optical system collectively as serial transform correlators (STCs). Despite being well known, misconceptions...

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O'Callaghan MJ, Perlmutter SH. Serial transform optical correlator design principles. Appl Opt. 2001;40(20):3311-7doi: 10.1364/ao.40.003311.
O'Callaghan, M. J., & Perlmutter, S. H. (2001). Serial transform optical correlator design principles. Applied optics, 40(20), 3311-7. https://doi.org/10.1364/ao.40.003311
O'Callaghan, M J, and Perlmutter, S H. "Serial transform optical correlator design principles." Applied optics vol. 40,20 (2001): 3311-7. doi: https://doi.org/10.1364/ao.40.003311
O'Callaghan MJ, Perlmutter SH. Serial transform optical correlator design principles. Appl Opt. 2001 Jul 10;40(20):3311-7. doi: 10.1364/ao.40.003311. PMID: 18360354.
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Seasonally of births in affective disorder in an Irish population.

European psychiatry : the journal of the Association of European Psychiatrists

Clarke M, Keogh F, Murphy P, Morris M, Larkin C, Walsh D, O'Callaghan E.
PMID: 19706265
Eur Psychiatry. 1998 Nov;13(7):353-8. doi: 10.1016/S0924-9338(99)80702-0.

Seasonal variation in the births of patients with schizophrenia is a consistently replicated epidemiological finding. Few studies have investigated this phenomenon among patients with a diagnosis of affective disorder. The majority of season of birth studies have employed the...

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Clarke M, Keogh F, Murphy P, et al. Seasonally of births in affective disorder in an Irish population. Eur Psychiatry. 1998;13(7):353-8doi: 10.1016/S0924-9338(99)80702-0.
Clarke, M., Keogh, F., Murphy, P., Morris, M., Larkin, C., Walsh, D., & O'Callaghan, E. (1998). Seasonally of births in affective disorder in an Irish population. European psychiatry : the journal of the Association of European Psychiatrists, 13(7), 353-8. https://doi.org/10.1016/S0924-9338(99)80702-0
Clarke, M, et al. "Seasonally of births in affective disorder in an Irish population." European psychiatry : the journal of the Association of European Psychiatrists vol. 13,7 (1998): 353-8. doi: https://doi.org/10.1016/S0924-9338(99)80702-0
Clarke M, Keogh F, Murphy P, Morris M, Larkin C, Walsh D, O'Callaghan E. Seasonally of births in affective disorder in an Irish population. Eur Psychiatry. 1998 Nov;13(7):353-8. doi: 10.1016/S0924-9338(99)80702-0. PMID: 19706265.
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Showing 1 to 12 of 377 entries