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[Proper use of laboratory tests from a perspective of health insurance administration].

Rinsho byori. The Japanese journal of clinical pathology

Okubo I.
PMID: 1507475
Rinsho Byori. 1992 May;40(5):502-6.

The national medical expenditure increases at a rate of 1 trillion yen a year, and the expenditure for 1992 is estimated to be about 23 trillion yen. One of the most important jobs of the Health Insurance Administration is...

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Okubo I. [Proper use of laboratory tests from a perspective of health insurance administration]. Rinsho Byori. 1992;40(5):502-6
Okubo, I. (1992). [Proper use of laboratory tests from a perspective of health insurance administration]. Rinsho byori. The Japanese journal of clinical pathology, 40(5), 502-6.
Okubo, I. "[Proper use of laboratory tests from a perspective of health insurance administration]." Rinsho byori. The Japanese journal of clinical pathology vol. 40,5 (1992): 502-6.
Okubo I. [Proper use of laboratory tests from a perspective of health insurance administration]. Rinsho Byori. 1992 May;40(5):502-6. Japanese. PMID: 1507475.
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The assessment of the optimal duration of early intervention with montelukast in the treatment of Japanese cedar pollinosis symptoms induced in an artificial exposure chamber.

Journal of drug assessment

Hashiguchi K, Okubo K, Wakabayashi K, Tanaka N, Watada Y, Suematsu K, Gotoh M.
PMID: 27536427
J Drug Assess. 2012 Oct 09;1(1):40-7. doi: 10.3109/21556660.2012.728547. eCollection 2012.

OBJECTIVE: The study objective was to investigate the prophylactic efficacy of montelukast (MLK) 10 mg in suppressing seasonal allergic rhinitis (SAR) symptoms induced by Japanese cedar (JC) pollen and to determine how many days before exposure to JC in...

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Hashiguchi K, Okubo K, Wakabayashi K, et al. The assessment of the optimal duration of early intervention with montelukast in the treatment of Japanese cedar pollinosis symptoms induced in an artificial exposure chamber. J Drug Assess. 2012;1(1):40-7doi: 10.3109/21556660.2012.728547.
Hashiguchi, K., Okubo, K., Wakabayashi, K., Tanaka, N., Watada, Y., Suematsu, K., & Gotoh, M. (2012). The assessment of the optimal duration of early intervention with montelukast in the treatment of Japanese cedar pollinosis symptoms induced in an artificial exposure chamber. Journal of drug assessment, 1(1), 40-7. https://doi.org/10.3109/21556660.2012.728547
Hashiguchi, Kazuhiro, et al. "The assessment of the optimal duration of early intervention with montelukast in the treatment of Japanese cedar pollinosis symptoms induced in an artificial exposure chamber." Journal of drug assessment vol. 1,1 (2012): 40-7. doi: https://doi.org/10.3109/21556660.2012.728547
Hashiguchi K, Okubo K, Wakabayashi K, Tanaka N, Watada Y, Suematsu K, Gotoh M. The assessment of the optimal duration of early intervention with montelukast in the treatment of Japanese cedar pollinosis symptoms induced in an artificial exposure chamber. J Drug Assess. 2012 Oct 09;1(1):40-7. doi: 10.3109/21556660.2012.728547. eCollection 2012. PMID: 27536427; PMCID: PMC4980728.
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The expression of IGF-1R in Helicobacter pylori-infected intestinal metaplasia and gastric cancer.

Journal of clinical biochemistry and nutrition

Nakajima N, Kozu K, Kobayashi S, Nishiyama R, Okubo R, Akai Y, Moriyama M, Kinukawa N.
PMID: 27499580
J Clin Biochem Nutr. 2016 Jul;59(1):53-7. doi: 10.3164/jcbn.16-11. Epub 2016 May 21.

Overexpression of IGF-1R has been demonstrated in gastrointestinal cancers, and its expression is reported as the result of the loss of tumor suppressors. IL-16 is involved in the pathophysiological process of chronic inflammatory diseases. The aim of this study...

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Nakajima N, Kozu K, Kobayashi S, et al. The expression of IGF-1R in Helicobacter pylori-infected intestinal metaplasia and gastric cancer. J Clin Biochem Nutr. 2016;59(1):53-7doi: 10.3164/jcbn.16-11.
Nakajima, N., Kozu, K., Kobayashi, S., Nishiyama, R., Okubo, R., Akai, Y., Moriyama, M., & Kinukawa, N. (2016). The expression of IGF-1R in Helicobacter pylori-infected intestinal metaplasia and gastric cancer. Journal of clinical biochemistry and nutrition, 59(1), 53-7. https://doi.org/10.3164/jcbn.16-11
Nakajima, Noriko, et al. "The expression of IGF-1R in Helicobacter pylori-infected intestinal metaplasia and gastric cancer." Journal of clinical biochemistry and nutrition vol. 59,1 (2016): 53-7. doi: https://doi.org/10.3164/jcbn.16-11
Nakajima N, Kozu K, Kobayashi S, Nishiyama R, Okubo R, Akai Y, Moriyama M, Kinukawa N. The expression of IGF-1R in Helicobacter pylori-infected intestinal metaplasia and gastric cancer. J Clin Biochem Nutr. 2016 Jul;59(1):53-7. doi: 10.3164/jcbn.16-11. Epub 2016 May 21. PMID: 27499580; PMCID: PMC4933692.
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Pediatric hypervirulent Klebsiella pneumoniae septic arthritis.

Pediatrics international : official journal of the Japan Pediatric Society

Kishibe S, Okubo Y, Morino S, Hirotaki S, Tame T, Aoki K, Ishii Y, Ota N, Shimomura S, Sakakibara H, Terakawa T, Horikoshi Y.
PMID: 27005513
Pediatr Int. 2016 May;58(5):382-385. doi: 10.1111/ped.12806. Epub 2016 Mar 23.

Cases of infection with hypervirulent Klebsiella pneumoniae are gradually increasing in number, and cause life-threatening community-acquired infection even in immunocompetent patients. A 14-year-old boy developed septic hip arthritis due to hypervirulent K. pneumoniae (sequence type 23, serotype K1, magA...

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Kishibe S, Okubo Y, Morino S, et al. Pediatric hypervirulent Klebsiella pneumoniae septic arthritis. Pediatr Int. 2016;58(5):382-385doi: 10.1111/ped.12806.
Kishibe, S., Okubo, Y., Morino, S., Hirotaki, S., Tame, T., Aoki, K., Ishii, Y., Ota, N., Shimomura, S., Sakakibara, H., Terakawa, T., & Horikoshi, Y. (2016). Pediatric hypervirulent Klebsiella pneumoniae septic arthritis. Pediatrics international : official journal of the Japan Pediatric Society, 58(5), 382-385. https://doi.org/10.1111/ped.12806
Kishibe, Shun, et al. "Pediatric hypervirulent Klebsiella pneumoniae septic arthritis." Pediatrics international : official journal of the Japan Pediatric Society vol. 58,5 (2016): 382-385. doi: https://doi.org/10.1111/ped.12806
Kishibe S, Okubo Y, Morino S, Hirotaki S, Tame T, Aoki K, Ishii Y, Ota N, Shimomura S, Sakakibara H, Terakawa T, Horikoshi Y. Pediatric hypervirulent Klebsiella pneumoniae septic arthritis. Pediatr Int. 2016 May;58(5):382-385. doi: 10.1111/ped.12806. Epub 2016 Mar 23. PMID: 27005513.
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A top-down methodology for ultrafast tuning of nanosized zeolites.

Chemical communications (Cambridge, England)

Liu Z, Nomura N, Nishioka D, Hotta Y, Matsuo T, Oshima K, Yanaba Y, Yoshikawa T, Ohara K, Kohara S, Takewaki T, Okubo T, Wakihara T.
PMID: 26154841
Chem Commun (Camb). 2015 Aug 14;51(63):12567-70. doi: 10.1039/c5cc04542h.

We herein present a top-down methodology to prepare nanosized zeolites with tunable size by combining post-synthesis milling and fast recrystallization of several minutes (10 min for SSZ-13 and 5 min for AlPO4-5). A continuous-flow recrystallization process is demonstrated to...

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Liu Z, Nomura N, Nishioka D, et al. A top-down methodology for ultrafast tuning of nanosized zeolites. Chem Commun (Camb). 2015;51(63):12567-70doi: 10.1039/c5cc04542h.
Liu, Z., Nomura, N., Nishioka, D., Hotta, Y., Matsuo, T., Oshima, K., Yanaba, Y., Yoshikawa, T., Ohara, K., Kohara, S., Takewaki, T., Okubo, T., & Wakihara, T. (2015). A top-down methodology for ultrafast tuning of nanosized zeolites. Chemical communications (Cambridge, England), 51(63), 12567-70. https://doi.org/10.1039/c5cc04542h
Liu, Zhendong, et al. "A top-down methodology for ultrafast tuning of nanosized zeolites." Chemical communications (Cambridge, England) vol. 51,63 (2015): 12567-70. doi: https://doi.org/10.1039/c5cc04542h
Liu Z, Nomura N, Nishioka D, Hotta Y, Matsuo T, Oshima K, Yanaba Y, Yoshikawa T, Ohara K, Kohara S, Takewaki T, Okubo T, Wakihara T. A top-down methodology for ultrafast tuning of nanosized zeolites. Chem Commun (Camb). 2015 Aug 14;51(63):12567-70. doi: 10.1039/c5cc04542h. PMID: 26154841.
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Daclatasvir and asunaprevir for genotype 1b chronic hepatitis C patients with chronic kidney disease.

Hepatology research : the official journal of the Japan Society of Hepatology

Kondo C, Atsukawa M, Tsubota A, Shimada N, Abe H, Asano T, Yoshizawa K, Okubo T, Chuganji Y, Aizawa Y, Iio E, Tanaka Y, Iwakiri K.
PMID: 28225572
Hepatol Res. 2017 Oct;47(11):1165-1173. doi: 10.1111/hepr.12879. Epub 2017 Apr 12.

AIM: To evaluate the efficacy and safety of daclatasvir and asunaprevir combined therapy in genotype 1b chronic hepatitis C patients with non-dialysis chronic kidney disease (CKD).METHODS: In a multicenter collaborative study, 249 patients received 60 mg daclatasvir (NS5A inhibitor)...

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Kondo C, Atsukawa M, Tsubota A, et al. Daclatasvir and asunaprevir for genotype 1b chronic hepatitis C patients with chronic kidney disease. Hepatol Res. 2017;47(11):1165-1173doi: 10.1111/hepr.12879.
Kondo, C., Atsukawa, M., Tsubota, A., Shimada, N., Abe, H., Asano, T., Yoshizawa, K., Okubo, T., Chuganji, Y., Aizawa, Y., Iio, E., Tanaka, Y., & Iwakiri, K. (2017). Daclatasvir and asunaprevir for genotype 1b chronic hepatitis C patients with chronic kidney disease. Hepatology research : the official journal of the Japan Society of Hepatology, 47(11), 1165-1173. https://doi.org/10.1111/hepr.12879
Kondo, Chisa, et al. "Daclatasvir and asunaprevir for genotype 1b chronic hepatitis C patients with chronic kidney disease." Hepatology research : the official journal of the Japan Society of Hepatology vol. 47,11 (2017): 1165-1173. doi: https://doi.org/10.1111/hepr.12879
Kondo C, Atsukawa M, Tsubota A, Shimada N, Abe H, Asano T, Yoshizawa K, Okubo T, Chuganji Y, Aizawa Y, Iio E, Tanaka Y, Iwakiri K. Daclatasvir and asunaprevir for genotype 1b chronic hepatitis C patients with chronic kidney disease. Hepatol Res. 2017 Oct;47(11):1165-1173. doi: 10.1111/hepr.12879. Epub 2017 Apr 12. PMID: 28225572.
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Coronenetetraimide-centered cruciform pentamers containing multiporphyrin units: synthesis and sequential photoinduced energy- and electron-transfer dynamics.

Chemistry (Weinheim an der Bergstrasse, Germany)

Hasobe T, Ida K, Sakai H, Ohkubo K, Fukuzumi S.
PMID: 26094912
Chemistry. 2015 Jul 27;21(31):11196-205. doi: 10.1002/chem.201500766. Epub 2015 Jun 19.

A series of coronenetetraimide (CorTIm)-centered cruciform pentamers containing multiporphyrin units, in which four porphyrin units are covalently linked to a CorTIm core through benzyl linkages, were designed and synthesized to investigate their structural, spectroscopic, and electrochemical properties as well...

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Hasobe T, Ida K, Sakai H, et al. Coronenetetraimide-centered cruciform pentamers containing multiporphyrin units: synthesis and sequential photoinduced energy- and electron-transfer dynamics. Chemistry. 2015;21(31):11196-205doi: 10.1002/chem.201500766.
Hasobe, T., Ida, K., Sakai, H., Ohkubo, K., & Fukuzumi, S. (2015). Coronenetetraimide-centered cruciform pentamers containing multiporphyrin units: synthesis and sequential photoinduced energy- and electron-transfer dynamics. Chemistry (Weinheim an der Bergstrasse, Germany), 21(31), 11196-205. https://doi.org/10.1002/chem.201500766
Hasobe, Taku, et al. "Coronenetetraimide-centered cruciform pentamers containing multiporphyrin units: synthesis and sequential photoinduced energy- and electron-transfer dynamics." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 21,31 (2015): 11196-205. doi: https://doi.org/10.1002/chem.201500766
Hasobe T, Ida K, Sakai H, Ohkubo K, Fukuzumi S. Coronenetetraimide-centered cruciform pentamers containing multiporphyrin units: synthesis and sequential photoinduced energy- and electron-transfer dynamics. Chemistry. 2015 Jul 27;21(31):11196-205. doi: 10.1002/chem.201500766. Epub 2015 Jun 19. PMID: 26094912.
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Gene duplication and genetic exchange drive the evolution of S-RNase-based self-incompatibility in Petunia.

Nature plants

Kubo K, Paape T, Hatakeyama M, Entani T, Takara A, Kajihara K, Tsukahara M, Shimizu-Inatsugi R, Shimizu KK, Takayama S.
PMID: 27246052
Nat Plants. 2015 Jan 08;1:14005. doi: 10.1038/nplants.2014.5.

Self-incompatibility (SI) systems in flowering plants distinguish self- and non-self pollen to prevent inbreeding. While other SI systems rely on the self-recognition between specific male- and female-determinants, the Solanaceae family has a non-self recognition system resulting in the detoxification...

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Kubo K, Paape T, Hatakeyama M, et al. Gene duplication and genetic exchange drive the evolution of S-RNase-based self-incompatibility in Petunia. Nat Plants. 2015;1:14005doi: 10.1038/nplants.2014.5.
Kubo, K., Paape, T., Hatakeyama, M., Entani, T., Takara, A., Kajihara, K., Tsukahara, M., Shimizu-Inatsugi, R., Shimizu, K. K., & Takayama, S. (2015). Gene duplication and genetic exchange drive the evolution of S-RNase-based self-incompatibility in Petunia. Nature plants, 114005. https://doi.org/10.1038/nplants.2014.5
Kubo, Ken-Ichi, et al. "Gene duplication and genetic exchange drive the evolution of S-RNase-based self-incompatibility in Petunia." Nature plants vol. 1 (2015): 14005. doi: https://doi.org/10.1038/nplants.2014.5
Kubo K, Paape T, Hatakeyama M, Entani T, Takara A, Kajihara K, Tsukahara M, Shimizu-Inatsugi R, Shimizu KK, Takayama S. Gene duplication and genetic exchange drive the evolution of S-RNase-based self-incompatibility in Petunia. Nat Plants. 2015 Jan 08;1:14005. doi: 10.1038/nplants.2014.5. PMID: 27246052.
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In Vivo Effects of Tea Polyphenol Intake on Human Intestinal Microflora and Metabolism.

Bioscience, biotechnology, and biochemistry

Okubo T, Ishihara N, Oura A, Serit M, Kim M, Yamamoto T, Mitsuoka T.
PMID: 27280652
Biosci Biotechnol Biochem. 1992 Jan;56(4):588-91. doi: 10.1271/bbb.56.588.

Effects of tea polyphenol intake (0.4 g/volunteer, 3 times per day, for four weeks) on fecal microflora, bacterial metabolites, and pH were investigated using eight healthy human volunteers. Counts for Clostridium perfringens and other Clostridium spp. were significantly decreased...

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Okubo T, Ishihara N, Oura A, et al. In Vivo Effects of Tea Polyphenol Intake on Human Intestinal Microflora and Metabolism. Biosci Biotechnol Biochem. 1992;56(4):588-91doi: 10.1271/bbb.56.588.
Okubo, T., Ishihara, N., Oura, A., Serit, M., Kim, M., Yamamoto, T., & Mitsuoka, T. (1992). In Vivo Effects of Tea Polyphenol Intake on Human Intestinal Microflora and Metabolism. Bioscience, biotechnology, and biochemistry, 56(4), 588-91. https://doi.org/10.1271/bbb.56.588
Okubo, T, et al. "In Vivo Effects of Tea Polyphenol Intake on Human Intestinal Microflora and Metabolism." Bioscience, biotechnology, and biochemistry vol. 56,4 (1992): 588-91. doi: https://doi.org/10.1271/bbb.56.588
Okubo T, Ishihara N, Oura A, Serit M, Kim M, Yamamoto T, Mitsuoka T. In Vivo Effects of Tea Polyphenol Intake on Human Intestinal Microflora and Metabolism. Biosci Biotechnol Biochem. 1992 Jan;56(4):588-91. doi: 10.1271/bbb.56.588. PMID: 27280652.
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Solvent-Free Photooxidation of Alkanes by Dioxygen with 2,3-Dichloro-5,6-dicyano-p-benzoquinone via Photoinduced Electron Transfer.

Chemistry, an Asian journal

Ohkubo K, Hirose K, Fukuzumi S.
PMID: 27399906
Chem Asian J. 2016 Aug 19;11(16):2255-9. doi: 10.1002/asia.201600828. Epub 2016 Aug 02.

Photooxidation of alkanes by dioxygen occurred under visible light irradiation of 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) which acts as a super photooxidant. Solvent-free hydroxylation of cyclohexane and alkanes is initiated by electron transfer from alkanes to the singlet and triplet excited states...

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Ohkubo K, Hirose K, Fukuzumi S. Solvent-Free Photooxidation of Alkanes by Dioxygen with 2,3-Dichloro-5,6-dicyano-p-benzoquinone via Photoinduced Electron Transfer. Chem Asian J. 2016;11(16):2255-9doi: 10.1002/asia.201600828.
Ohkubo, K., Hirose, K., & Fukuzumi, S. (2016). Solvent-Free Photooxidation of Alkanes by Dioxygen with 2,3-Dichloro-5,6-dicyano-p-benzoquinone via Photoinduced Electron Transfer. Chemistry, an Asian journal, 11(16), 2255-9. https://doi.org/10.1002/asia.201600828
Ohkubo, Kei, et al. "Solvent-Free Photooxidation of Alkanes by Dioxygen with 2,3-Dichloro-5,6-dicyano-p-benzoquinone via Photoinduced Electron Transfer." Chemistry, an Asian journal vol. 11,16 (2016): 2255-9. doi: https://doi.org/10.1002/asia.201600828
Ohkubo K, Hirose K, Fukuzumi S. Solvent-Free Photooxidation of Alkanes by Dioxygen with 2,3-Dichloro-5,6-dicyano-p-benzoquinone via Photoinduced Electron Transfer. Chem Asian J. 2016 Aug 19;11(16):2255-9. doi: 10.1002/asia.201600828. Epub 2016 Aug 02. PMID: 27399906.
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Evaluation of contrast-enhanced ultrasonography for hepatocellular carcinoma prior to and following stereotactic body radiation therapy using the CyberKnife® system: A preliminary report.

Oncology letters

Shiozawa K, Watanabe M, Ikehara T, Kobayashi K, Ochi Y, Suzuki Y, Fuchinoue K, Yoneda M, Kenmochi T, Okubo Y, Mori T, Makino H, Tsukamoto N, Igarashi Y, Sumino Y.
PMID: 26870190
Oncol Lett. 2016 Jan;11(1):208-212. doi: 10.3892/ol.2015.3874. Epub 2015 Nov 05.

The CyberKnife® is expected to be a novel local treatment for hepatocellular carcinoma (HCC), however, a long-term follow-up using dynamic computed tomography and magnetic resonance imaging is required to determine the effect of treatment in a number of the...

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Shiozawa K, Watanabe M, Ikehara T, et al. Evaluation of contrast-enhanced ultrasonography for hepatocellular carcinoma prior to and following stereotactic body radiation therapy using the CyberKnife® system: A preliminary report. Oncol Lett. 2015;11(1):208-212doi: 10.3892/ol.2015.3874.
Shiozawa, K., Watanabe, M., Ikehara, T., Kobayashi, K., Ochi, Y., Suzuki, Y., Fuchinoue, K., Yoneda, M., Kenmochi, T., Okubo, Y., Mori, T., Makino, H., Tsukamoto, N., Igarashi, Y., & Sumino, Y. (2016). Evaluation of contrast-enhanced ultrasonography for hepatocellular carcinoma prior to and following stereotactic body radiation therapy using the CyberKnife® system: A preliminary report. Oncology letters, 11(1), 208-212. https://doi.org/10.3892/ol.2015.3874
Shiozawa, Kazue, et al. "Evaluation of contrast-enhanced ultrasonography for hepatocellular carcinoma prior to and following stereotactic body radiation therapy using the CyberKnife® system: A preliminary report." Oncology letters vol. 11,1 (2016): 208-212. doi: https://doi.org/10.3892/ol.2015.3874
Shiozawa K, Watanabe M, Ikehara T, Kobayashi K, Ochi Y, Suzuki Y, Fuchinoue K, Yoneda M, Kenmochi T, Okubo Y, Mori T, Makino H, Tsukamoto N, Igarashi Y, Sumino Y. Evaluation of contrast-enhanced ultrasonography for hepatocellular carcinoma prior to and following stereotactic body radiation therapy using the CyberKnife® system: A preliminary report. Oncol Lett. 2016 Jan;11(1):208-212. doi: 10.3892/ol.2015.3874. Epub 2015 Nov 05. PMID: 26870190; PMCID: PMC4727166.
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Fatigue Alters Landing Shock Attenuation During a Single-Leg Vertical Drop Jump.

Orthopaedic journal of sports medicine

Tamura A, Akasaka K, Otsudo T, Sawada Y, Okubo Y, Shiozawa J, Toda Y, Yamada K.
PMID: 26811843
Orthop J Sports Med. 2016 Jan 14;4(1):2325967115626412. doi: 10.1177/2325967115626412. eCollection 2016 Jan.

BACKGROUND: Landings in fatigue conditions are considered to be one of the factors that cause noncontact anterior cruciate ligament (ACL) injury. Additionally, it is known that fatigue alters lower extremity landing strategies and decreases the ability to attenuate shock...

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Tamura A, Akasaka K, Otsudo T, et al. Fatigue Alters Landing Shock Attenuation During a Single-Leg Vertical Drop Jump. Orthop J Sports Med. 2016;4(1):2325967115626412doi: 10.1177/2325967115626412.
Tamura, A., Akasaka, K., Otsudo, T., Sawada, Y., Okubo, Y., Shiozawa, J., Toda, Y., & Yamada, K. (2016). Fatigue Alters Landing Shock Attenuation During a Single-Leg Vertical Drop Jump. Orthopaedic journal of sports medicine, 4(1), 2325967115626412. https://doi.org/10.1177/2325967115626412
Tamura, Akihiro, et al. "Fatigue Alters Landing Shock Attenuation During a Single-Leg Vertical Drop Jump." Orthopaedic journal of sports medicine vol. 4,1 (2016): 2325967115626412. doi: https://doi.org/10.1177/2325967115626412
Tamura A, Akasaka K, Otsudo T, Sawada Y, Okubo Y, Shiozawa J, Toda Y, Yamada K. Fatigue Alters Landing Shock Attenuation During a Single-Leg Vertical Drop Jump. Orthop J Sports Med. 2016 Jan 14;4(1):2325967115626412. doi: 10.1177/2325967115626412. eCollection 2016 Jan. PMID: 26811843; PMCID: PMC4716402.
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