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Showing 1 to 12 of 110 entries
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JAG: A Computational Tool to Evaluate the Role of Gene-Sets in Complex Traits.

Genes

Lips ES, Kooyman M, de Leeuw C, Posthuma D.
PMID: 26110313
Genes (Basel). 2015 May 14;6(2):238-51. doi: 10.3390/genes6020238.

Gene-set analysis has been proposed as a powerful tool to deal with the highly polygenic architecture of complex traits, as well as with the small effect sizes typically found in GWAS studies for complex traits. We developed a tool,...

Reprint of Inter-comparison of boron concentration measurements at INFN-University of Pavia (Italy) and CNEA (Argentina).

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

Portu A, Postuma I, Gadan MA, Saint Martin G, Olivera MS, Altieri S, Protti N, Bortolussi S.
PMID: 26508276
Appl Radiat Isot. 2015 Dec;106:171-5. doi: 10.1016/j.apradiso.2015.10.012. Epub 2015 Oct 21.

An inter-comparison of three boron determination techniques was carried out between laboratories from INFN-University of Pavia (Italy) and CNEA (Argentina): alpha spectrometry (alpha-spect), neutron capture radiography (NCR) and quantitative autoradiography (QTA). Samples of different nature were analysed: liquid standards,...

Inducing fluorescence of uranyl acetate as a dual-purpose contrast agent for correlative light-electron microscopy with nanometre precision.

Scientific reports

Tuijtel MW, Mulder AA, Posthuma CC, van der Hoeven B, Koster AJ, Bárcena M, Faas FGA, Sharp TH.
PMID: 28874723
Sci Rep. 2017 Sep 05;7(1):10442. doi: 10.1038/s41598-017-10905-x.

Correlative light-electron microscopy (CLEM) combines the high spatial resolution of transmission electron microscopy (TEM) with the capability of fluorescence light microscopy (FLM) to locate rare or transient cellular events within a large field of view. CLEM is therefore a...

Basic clinical features do not predict dopamine transporter binding in idiopathic REM behavior disorder.

NPJ Parkinson's disease

Chahine LM, Iranzo A, Fernández-Arcos A, Simuni T, Seedorff N, Caspell-Garcia C, Amara AW, Comella C, Högl B, Hamilton J, Marek K, Mayer G, Mollenhauer B, Postuma R, Tolosa E, Trenkwalder C, Videnovic A, Oertel W.
PMID: 30701189
NPJ Parkinsons Dis. 2019 Jan 29;5:2. doi: 10.1038/s41531-018-0073-1. eCollection 2019.

REM sleep behavior disorder (RBD) is strongly associated with development of Parkinson's Disease and other α-synuclein-related disorders. Dopamine transporter (DAT) binding deficit predicts conversion to α-synuclein-related disorders in individuals with RBD. In turn, identifying which individuals with RBD have...

Simplifying environmental mixtures-An aquatic exposure-based approach via land use scenarios.

Environmental toxicology and chemistry

Posthuma L, Brown C, de Zwart D, Diamond J, Dyer SD, Hamer M, Holmes CM, Marshall S, Burton GA.
PMID: 29480978
Environ Toxicol Chem. 2018 Mar;37(3):671-673. doi: 10.1002/etc.4063.

No abstract available.

Imaging the Antistaphylococcal Activity of CATH-2: Mechanism of Attack and Regulation of Inflammatory Response.

mSphere

Schneider VAF, Coorens M, Tjeerdsma-van Bokhoven JLM, Posthuma G, van Dijk A, Veldhuizen EJA, Haagsman HP.
PMID: 29104934
mSphere. 2017 Nov 01;2(6). doi: 10.1128/mSphere.00370-17. eCollection 2017.

Chicken cathelicidin-2 (CATH-2) is a broad-spectrum antimicrobial host defense peptide (HDP) that may serve as a paradigm for the development of new antimicrobial agents. While previous studies have elucidated the mechanism by which CATH-2 kills

An improved neutron autoradiography set-up for (10)B concentration measurements in biological samples.

Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

Postuma I, Bortolussi S, Protti N, Ballarini F, Bruschi P, Ciani L, Ristori S, Panza L, Ferrari C, Cansolino L, Altieri S.
PMID: 26933395
Rep Pract Oncol Radiother. 2016 Mar-Apr;21(2):123-8. doi: 10.1016/j.rpor.2015.10.006. Epub 2015 Nov 14.

AIM: Boron Neutron Capture Therapy (BNCT) is a binary hadrontherapy which exploits the neutron capture reaction in boron, together with a selective uptake of boronated substances by the neoplastic tissue. There is increasing evidence that future improvements in clinical...

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.

Science (New York, N.Y.)

Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh BZ, Amin N, Barnard J, Baumeister SE, Benke KS, Bielak LF, Boatman JA, Boyle PA, Davies G, de Leeuw C, Eklund N, Evans DS, Ferhmann R, Fischer K, Gieger C, Gjessing HK, Hägg S, Harris JR, Hayward C, Holzapfel C, Ibrahim-Verbaas CA, Ingelsson E, Jacobsson B, Joshi PK, Jugessur A, Kaakinen M, Kanoni S, Karjalainen J, Kolcic I, Kristiansson K, Kutalik Z, Lahti J, Lee SH, Lin P, Lind PA, Liu Y, Lohman K, Loitfelder M, McMahon G, Vidal PM, Meirelles O, Milani L, Myhre R, Nuotio ML, Oldmeadow CJ, Petrovic KE, Peyrot WJ, Polasek O, Quaye L, Reinmaa E, Rice JP, Rizzi TS, Schmidt H, Schmidt R, Smith AV, Smith JA, Tanaka T, Terracciano A, van der Loos MJ, Vitart V, Völzke H, Wellmann J, Yu L, Zhao W, Allik J, Attia JR, Bandinelli S, Bastardot F, Beauchamp J, Bennett DA, Berger K, Bierut LJ, Boomsma DI, Bültmann U, Campbell H, Chabris CF, Cherkas L, Chung MK, Cucca F, de Andrade M, De Jager PL, De Neve JE, Deary IJ, Dedoussis GV, Deloukas P, Dimitriou M, Eiríksdóttir G, Elderson MF, Eriksson JG, Evans DM, Faul JD, Ferrucci L, Garcia ME, Grönberg H, Guðnason V, Hall P, Harris JM, Harris TB, Hastie ND, Heath AC, Hernandez DG, Hoffmann W, Hofman A, Holle R, Holliday EG, Hottenga JJ, Iacono WG, Illig T, Järvelin MR, Kähönen M, Kaprio J, Kirkpatrick RM, Kowgier M, Latvala A, Launer LJ, Lawlor DA, Lehtimäki T, Li J, Lichtenstein P, Lichtner P, Liewald DC, Madden PA, Magnusson PK, Mäkinen TE, Masala M, McGue M, Metspalu A, Mielck A, Miller MB, Montgomery GW, Mukherjee S, Nyholt DR, Oostra BA, Palmer LJ, Palotie A, Penninx BW, Perola M, Peyser PA, Preisig M, Räikkönen K, Raitakari OT, Realo A, Ring SM, Ripatti S, Rivadeneira F, Rudan I, Rustichini A, Salomaa V, Sarin AP, Schlessinger D, Scott RJ, Snieder H, St Pourcain B, Starr JM, Sul JH, Surakka I, Svento R, Teumer A, Tiemeier H, van Rooij FJ, Van Wagoner DR, Vartiainen E, Viikari J, Vollenweider P, Vonk JM, Waeber G, Weir DR, Wichmann HE, Widen E, Willemsen G, Wilson JF, Wright AF, Conley D, Davey-Smith G, Franke L, Groenen PJ, Hofman A, Johannesson M, Kardia SL, Krueger RF, Laibson D, Martin NG, Meyer MN, Posthuma D, Thurik AR, Timpson NJ, Uitterlinden AG, van Duijn CM, Visscher PM, Benjamin DJ, Cesarini D, Koellinger PD.
PMID: 23722424
Science. 2013 Jun 21;340(6139):1467-71. doi: 10.1126/science.1235488. Epub 2013 May 30.

A genome-wide association study (GWAS) of educational attainment was conducted in a discovery sample of 101,069 individuals and a replication sample of 25,490. Three independent single-nucleotide polymorphisms (SNPs) are genome-wide significant (rs9320913, rs11584700, rs4851266), and all three replicate. Estimated...

Anonymous Dutch sperm donors releasing their identity.

Human fertility (Cambridge, England)

Bolt S, Postema D, van der Heij A, B M Maas AJ.
PMID: 30652500
Hum Fertil (Camb). 2021 Feb;24(1):24-30. doi: 10.1080/14647273.2018.1564156. Epub 2019 Jan 17.

This study examined the motivations of anonymous Dutch sperm donors to release their identity. It aimed to increase knowledge and encourage donors to become identifiable through a more informed decision, allowing more donor-conceived persons to contact their donors. Since...

Reply to "Concerns About Reproducibility, Use of the Akaike Information Criterion, and Related Issues in Hoondert et al. 2019" and Focus in Developing QSAR-Based Species Sensitivity Distributions.

Environmental toxicology and chemistry

Hoondert RPJ, Oldenkamp R, de Zwart D, van de Meent D, Posthuma L.
PMID: 32583909
Environ Toxicol Chem. 2020 Jul;39(7):1302-1304. doi: 10.1002/etc.4737.

No abstract available.

The observed respiratory rate of ward patients in the postoperative period.

Journal of clinical anesthesia

Posthuma LM, Visscher MJ, Dongelmans DA, Jessurun EN, Wissink IJA, van Etten-Jamaludin FS, Hollmann MW, Preckel B.
PMID: 34763272
J Clin Anesth. 2022 Feb;76:110578. doi: 10.1016/j.jclinane.2021.110578. Epub 2021 Nov 08.

No abstract available.

Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in .

Proceedings of the National Academy of Sciences of the United States of America

Ogando NS, El Kazzi P, Zevenhoven-Dobbe JC, Bontes BW, Decombe A, Posthuma CC, Thiel V, Canard B, Ferron F, Decroly E, Snijder EJ.
PMID: 34845015
Proc Natl Acad Sci U S A. 2021 Dec 07;118(49). doi: 10.1073/pnas.2108709118.

As coronaviruses (CoVs) replicate in the host cell cytoplasm, they rely on their own capping machinery to ensure the efficient translation of their messenger RNAs (mRNAs), protect them from degradation by cellular 5' exoribonucleases (ExoNs), and escape innate immune...

Showing 1 to 12 of 110 entries