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Showing 1 to 12 of 34 entries
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The split nature of tumor-infiltrating leukocytes: Implications for cancer surveillance and immunotherapy.

Oncoimmunology

Lança T, Silva-Santos B.
PMID: 22934263
Oncoimmunology. 2012 Aug 01;1(5):717-725. doi: 10.4161/onci.20068.

An important development in tumor immunology was the identification of highly diverse tumor-infiltrating leukocyte subsets that can play strikingly antagonistic functions. Namely, "anti-tumor" vs. "pro-tumor" roles have been suggested for Th1 and Th17 subsets of CD4(+) T cells, Type...

Five Layers of Receptor Signaling in γδ T-Cell Differentiation and Activation.

Frontiers in immunology

Ribeiro ST, Ribot JC, Silva-Santos B.
PMID: 25674089
Front Immunol. 2015 Jan 26;6:15. doi: 10.3389/fimmu.2015.00015. eCollection 2015.

The contributions of γδ T-cells to immunity to infection or tumors critically depend on their activation and differentiation into effectors capable of secreting cytokines and killing infected or transformed cells. These processes are molecularly controlled by surface receptors that...

Multifaceted CK2 in malignant and healthy T cells.

Oncotarget

Ribeiro ST, Barata JT, Silva-Santos B.
PMID: 29207585
Oncotarget. 2017 Oct 09;8(53):90622-90623. doi: 10.18632/oncotarget.21700. eCollection 2017 Oct 31.

No abstract available.

BONE MINERAL DENSITY AND BODY COMPOSITION IN ELDERLY RUNNERS: SIX-YEAR FOLLOW-UP.

Acta ortopedica brasileira

Alonso AC, Ernandes RC, Pereira RHM, Becker RA, Machado-Lima A, Silva-Santos PR, Greve JMD, Garcez-Leme LE.
PMID: 30988653
Acta Ortop Bras. 2019 Mar-Apr;27(2):92-94. doi: 10.1590/1413-785220192702214897.

OBJECTIVE: To evaluate bone mineral density (BMD) and body composition over a six-year period in elderly long-distance runners.METHODS: We analyzed the medical records of elderly athletes who were long-distance runners, were participants of the IOT-HCFMUSP Orthogeriatric Group, and had...

MicroRNA-181a restricts human γδ T cell differentiation by targeting Map3k2 and Notch2.

EMBO reports

Gordino G, Costa-Pereira S, Corredeira P, Alves P, Costa L, Gomes AQ, Silva-Santos B, Ribot JC.
PMID: 34821000
EMBO Rep. 2022 Jan 05;23(1):e52234. doi: 10.15252/embr.202052234. Epub 2021 Nov 24.

γδ T cells are a conserved population of lymphocytes that contributes to anti-tumor responses through its overt type 1 inflammatory and cytotoxic properties. We have previously shown that human γδ T cells acquire this profile upon stimulation with IL-2...

Interventions That Successfully Reduced Adults Salt Intake-A Systematic Review.

Nutrients

Silva-Santos T, Moreira P, Rodrigues M, Padrão P, Pinho O, Norton P, Ndrio A, Gonçalves C.
PMID: 35010883
Nutrients. 2021 Dec 21;14(1). doi: 10.3390/nu14010006.

BACKGROUND: Adequate sodium intake is important for lowering blood pressure and thus reducing cardiovascular disease risk and other complications. The aim of this review is to identify recent interventions around the world that have been successful in reducing salt...

Interventions That Successfully Reduced Adults Salt Intake-A Systematic Review.

Nutrients

Silva-Santos T, Moreira P, Rodrigues M, Padrão P, Pinho O, Norton P, Ndrio A, Gonçalves C.
PMID: 35010883
Nutrients. 2021 Dec 21;14(1). doi: 10.3390/nu14010006.

BACKGROUND: Adequate sodium intake is important for lowering blood pressure and thus reducing cardiovascular disease risk and other complications. The aim of this review is to identify recent interventions around the world that have been successful in reducing salt...

MicroRNA-181a restricts human γδ T cell differentiation by targeting Map3k2 and Notch2.

EMBO reports

Gordino G, Costa-Pereira S, Corredeira P, Alves P, Costa L, Gomes AQ, Silva-Santos B, Ribot JC.
PMID: 34821000
EMBO Rep. 2022 Jan 05;23(1):e52234. doi: 10.15252/embr.202052234. Epub 2021 Nov 24.

γδ T cells are a conserved population of lymphocytes that contributes to anti-tumor responses through its overt type 1 inflammatory and cytotoxic properties. We have previously shown that human γδ T cells acquire this profile upon stimulation with IL-2...

MicroRNA-181a restricts human γδ T cell differentiation by targeting Map3k2 and Notch2.

EMBO reports

Gordino G, Costa-Pereira S, Corredeira P, Alves P, Costa L, Gomes AQ, Silva-Santos B, Ribot JC.
PMID: 34821000
EMBO Rep. 2021 Nov 24;e52234. doi: 10.15252/embr.202052234. Epub 2021 Nov 24.

γδ T cells are a conserved population of lymphocytes that contributes to anti-tumor responses through its overt type 1 inflammatory and cytotoxic properties. We have previously shown that human γδ T cells acquire this profile upon stimulation with IL-2...

Comparison of the Oxidative Stability and Antioxidant Activity of Extra-Virgin Olive Oil and Oils Extracted from Seeds of .

Antioxidants (Basel, Switzerland)

Abril D, Mirabal-Gallardo Y, González A, Marican A, Durán-Lara EF, Silva Santos L, Valdés O.
PMID: 31601036
Antioxidants (Basel). 2019 Oct 09;8(10). doi: 10.3390/antiox8100470.

We investigated the potential of two oil extracts from seeds of

Toward a better understanding of T cells in cancer.

Cancer cell

Oh DY, Fong L, Newell EW, Turk MJ, Chi H, Chang HY, Satpathy AT, Fairfax B, Silva-Santos B, Lantz O.
PMID: 34906313
Cancer Cell. 2021 Dec 13;39(12):1549-1552. doi: 10.1016/j.ccell.2021.11.010.

T cells mediate anti-tumor immune responses and are the key target of immune checkpoint therapy, but they can also promote immune tolerance. A clear understanding of the specific contributions and biology of different T cell subsets is required to...

Non-suicidal self-injury and suicidal behavior during the COVID-19 pandemic in Brazil.

Death studies

Faro A, Lisboa W, Silva-Santos LC, Falcão-Lima GO.
PMID: 34534034
Death Stud. 2021 Sep 17;1-9. doi: 10.1080/07481187.2021.1978116. Epub 2021 Sep 17.

This study sought to determine the explanatory variables behind suicidal behavior and non-suicidal self-injury during the early months of the COVID-19 pandemic in Brazil. The sample comprised 4797 adults, who filled out a series of standardized instruments and additional...

Showing 1 to 12 of 34 entries