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Showing 1 to 12 of 43 entries
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The Pro12Ala polymorphism in the PPAR-γ2 gene is not associated to obesity and type 2 diabetes mellitus in a Cameroonian population.

BMC obesity

Mato EPM, Pokam-Fosso PE, Atogho-Tiedeu B, Noubiap JJN, Evehe MS, Djokam-Dadjeu R, Donfack OS, Ngwa EN, Guewo-Fokeng M, Mbacham WF, Sobngwi E, Mbanya JC.
PMID: 27239321
BMC Obes. 2016 May 12;3:26. doi: 10.1186/s40608-016-0104-6. eCollection 2016.

BACKGROUND: Peroxisome proliferator-activated receptor gamma 2 (PPAR-γ2) is a transcription factor with a key role in adipocyte differentiation, lipid storage and glucose homeostasis. The Ala allele of the common Pro12Ala polymorphism in the isoform PPAR-γ2 is at the center...

Association of the leptin-to-adiponectin ratio with metabolic syndrome in a sub-Saharan African population.

Diabetology & metabolic syndrome

Ayina CNA, Endomba FTA, Mandengue SH, Noubiap JJN, Ngoa LSE, Boudou P, Gautier JF, Mbanya JC, Sobngwi E.
PMID: 28878827
Diabetol Metab Syndr. 2017 Sep 05;9:66. doi: 10.1186/s13098-017-0265-6. eCollection 2017.

BACKGROUND: Worldwide there is an increased prevalence of metabolic syndrome mainly due to life-style modifications, and Africans are not saved of this situation. Many markers have been studied to predict the risk of this syndrome but the most used...

Metabolic effects of exposure to pesticides during gestation in female Wistar rats and their offspring: a risk factor for diabetes?.

Toxicological research

Ndonwi EN, Atogho-Tiedeu B, Lontchi-Yimagou E, Shinkafi TS, Nanfa D, Balti EV, Katte JC, Mbanya A, Matsha T, Mbanya JC, Shakir A, Sobngwi E.
PMID: 32685429
Toxicol Res. 2020 Feb 04;36(3):249-256. doi: 10.1007/s43188-019-00028-y. eCollection 2020 Jul.

Some pesticides increase the risk of type 2 diabetes, but whether fetal exposure carries transgenerational risk remains unknown. We evaluated the metabolic effects of gestational exposure to chlorpyrifos and imidacloprid in female Wistar rats and their offspring. We studied...

HIV treatment is associated with a two-fold higher probability of raised triglycerides: Pooled Analyses in 21 023 individuals in sub-Saharan Africa.

Global health, epidemiology and genomics

Ekoru K, Young EH, Dillon DG, Gurdasani D, Stehouwer N, Faurholt-Jepsen D, Levitt NS, Crowther NJ, Nyirenda M, Njelekela MA, Ramaiya K, Nyan O, Adewole OO, Anastos K, Compostella C, Dave JA, Fourie CM, Friis H, Kruger IM, Longenecker CT, Maher DP, Mutimura E, Ndhlovu CE, Praygod G, Pefura Yone EW, Pujades-Rodriguez M, Range N, Sani MU, Sanusi M, Schutte AE, Sliwa K, Tien PC, Vorster EH, Walsh C, Gareta D, Mashili F, Sobngwi E, Adebamowo C, Kamali A, Seeley J, Smeeth L, Pillay D, Motala AA, Kaleebu P, Sandhu MS.
PMID: 29881632
Glob Health Epidemiol Genom. 2018;3. doi: 10.1017/gheg.2018.7. Epub 2018 May 08.

BACKGROUND: Anti-retroviral therapy (ART) regimes for HIV are associated with raised levels of circulating triglycerides (TG) in western populations. However, there are limited data on the impact of ART on cardiometabolic risk in sub-Saharan African (SSA) populations.METHODS: Pooled analyses...

Effects of non-surgical treatment of chronic periodontitis on insulin resistance and glucose tolerance in subjects without diabetes (PARODIA 2 study).

Journal of investigative medicine : the official publication of the American Federation for Clinical Research

Nana Nana AR, Tsobgny Tsague NF, Lontchi-Yimagou E, Bengondo Messanga C, Tankeu A, Katte JC, Balti Vounsia E, Dehayem M, Sobngwi E.
PMID: 34261767
J Investig Med. 2021 Oct;69(7):1377-1381. doi: 10.1136/jim-2021-001831. Epub 2021 Jul 14.

This study aimed to assess the effects of non-surgical periodontal treatment (NSPT) of chronic periodontitis on insulin sensitivity, glucose tolerance, and serum C reactive protein (CRP) level in individuals without diabetes. Twenty individuals without diabetes with chronic periodontitis underwent...

Research priorities for accelerating the achievement of three 95 HIV goals in Cameroon: a consensus statement from the Cameroon HIV Research Forum (CAM-HERO).

The Pan African medical journal

Dzudie A, Tchounga B, Ajeh R, Kouanfack C, Ebasone PV, Djikeussi T, Nyoto LB, Fokam J, Ateudjieu J, Tchendjou P, Semengue ENJ, Kamgang FY, Anoubessi J, Varloteaux M, Youngui B, Tabala FN, Atanga B, Simo L, Zemsi A, Shu EN, Ndayisaba G, Nyenti A, Ntabe AC, Bwemba TA, Sobngwi E, Billong SC, Ditekemena J, Bissek ACZ, Njock LR.
PMID: 34909092
Pan Afr Med J. 2021 Oct 29;40:124. doi: 10.11604/pamj.2021.40.124.31068. eCollection 2021.

INTRODUCTION: the Treat-All remains the globally endorsed approach to attain the 95-95-95 targets and end the AIDS pandemic by 2030, but requires some country-level contextualization. In Cameroon, the specific research agenda to inform strategies for improving HIV policy was...

The Follow-Up and Well-Being of Geriatric Outpatients During COVID-19 Pandemic in Cameroon: Insights From the Yaounde Central Hospital.

Gerontology & geriatric medicine

Ntsama Essomba MJ, Nzana V, Noubiap JJ, Zingui-Ottou M, Ciaffi L, Sobngwi E, Ashuntantang G.
PMID: 33029549
Gerontol Geriatr Med. 2020 Sep 25;6:2333721420959242. doi: 10.1177/2333721420959242. eCollection 2020.

Although total confinement has not been adopted by the government of Cameroon, the COVID-19 pandemic is keeping geriatric patients out of hospital, despite a decline in their health status. In addition, the pandemic might have a significant effect on...

Expert Opinion: Patient Selection for Premixed Insulin Formulations in Diabetes Care.

Diabetes therapy : research, treatment and education of diabetes and related disorders

Kalra S, Czupryniak L, Kilov G, Lamptey R, Kumar A, Unnikrishnan AG, Boudiba A, Abid M, Akanov ZA, Latheef A, Araz M, Audehm R, Bahendeka S, Balde N, Chaudhary S, Deerochanawong C, Fasanmade O, Iraqi H, Latt TS, Mbanya JC, Rodriguez-Saldana J, Hyun KS, Latif ZA, Lushchyk M, Megallaa M, Naseri MW, Bay NQ, Ramaiya K, Randeree H, Raza SA, Shaikh K, Shrestha D, Sobngwi E, Somasundaram N, Sukor N, Tan R.
PMID: 30390228
Diabetes Ther. 2018 Dec;9(6):2185-2199. doi: 10.1007/s13300-018-0521-2. Epub 2018 Nov 03.

Premixed insulins are an important tool for glycemic control in persons with diabetes. Equally important in diabetes care is the selection of the most appropriate insulin regimen for a particular individual at a specific time. Currently, the choice of...

Setting-up nurse-led pilot clinics for the management of non-communicable diseases at primary health care level in resource-limited settings of Africa.

The Pan African medical journal

Kengne AP, Sobngwi E, Fezeu L, Awah PK, Dongmo S, Mbanya JC.
PMID: 21532719
Pan Afr Med J. 2009 Oct 24;3:10.

BACKGROUND: This article describes the setting-up process for nurse-led pilot clinics for the management of four chronic diseases: asthma, type 2 diabetes mellitus, epilepsy and hypertension at the primary health care level in urban and rural Cameroon.METHODS: The Biyem-Assi...

Erratum to: Investigation of the association between the TCF7L2 rs7903146 (C/T) gene polymorphism and obesity in a Cameroonian population: a pilot study.

Journal of health, population, and nutrition

Nguimmo-Metsadjio A, Atogho-Tiedeu B, Noubiap JJ, Evehe MS, Djokam-Dadjeu R, Donfack OS, Nanfa D, Mato EPM, Ngwa EN, Guewo-Fokeng M, Pokam-Fosso P, Mbacham WF, Mbanya JC, Sobngwi E.
PMID: 28511671
J Health Popul Nutr. 2017 May 16;36(1):16. doi: 10.1186/s41043-017-0094-0.

No abstract available.

Persistent organic pollutants as risk factors for type 2 diabetes.

Diabetology & metabolic syndrome

Ngwa EN, Kengne AP, Tiedeu-Atogho B, Mofo-Mato EP, Sobngwi E.
PMID: 25987904
Diabetol Metab Syndr. 2015 Apr 30;7:41. doi: 10.1186/s13098-015-0031-6. eCollection 2015.

Type 2 diabetes mellitus (T2DM) is a major and fast growing public health problem. Although obesity is considered to be the main driver of the pandemic of T2DM, a possible contribution of some environmental contaminants, of which persistent organic...

Osteoprotegerin in relation to insulin resistance and blood lipids in sub-Saharan African women with and without abdominal obesity.

Diabetology & metabolic syndrome

Ayina Ayina CN, Sobngwi E, Essouma M, Noubiap JJ, Boudou P, Etoundi Ngoa LS, Gautier JF.
PMID: 26034511
Diabetol Metab Syndr. 2015 May 23;7:47. doi: 10.1186/s13098-015-0042-3. eCollection 2015.

BACKGROUND: Osteoprotegerin (OPG), a soluble member of the tumor necrosis factor receptor superfamily that inhibits bone resorption, has been suggested as a potential marker of cardiovascular risk. This study aimed to assess the relationship between insulin resistance, lipid profile...

Showing 1 to 12 of 43 entries