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Showing 1 to 12 of 409 entries
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Characterization of candidate genes in inflammatory bowel disease-associated risk loci.

JCI insight

Peloquin JM, Goel G, Kong L, Huang H, Haritunians T, Sartor RB, Daly MJ, Newberry RD, McGovern DP, Yajnik V, Lira SA, Xavier RJ.
PMID: 27668286
JCI Insight. 2016 Aug 18;1(13):e87899. doi: 10.1172/jci.insight.87899.

GWAS have linked SNPs to risk of inflammatory bowel disease (IBD), but a systematic characterization of disease-associated genes has been lacking. Prior studies utilized microarrays that did not capture many genes encoded within risk loci or defined expression quantitative...

Response to pulmonary arterial hypertension drug therapies in patients with pulmonary arterial hypertension and cardiovascular risk factors.

Pulmonary circulation

Charalampopoulos A, Howard LS, Tzoulaki I, Gin-Sing W, Grapsa J, Wilkins MR, Davies RJ, Nihoyannopoulos P, Connolly SB, Gibbs JS.
PMID: 25610602
Pulm Circ. 2014 Dec;4(4):669-78. doi: 10.1086/678512.

The age at diagnosis of pulmonary arterial hypertension (PAH) and the prevalence of cardiovascular (CV) risk factors are increasing. We sought to determine whether the response to drug therapy was influenced by CV risk factors in PAH patients. We...

Preventing Filipino Mental Health Disparities: Perspectives from Adolescents, Caregivers, Providers, and Advocates.

Asian American journal of psychology

Javier JR, Supan J, Lansang A, Beyer W, Kubicek K, Palinkas LA.
PMID: 25667725
Asian Am J Psychol. 2014 Dec;5(4):316-324. doi: 10.1037/a0036479.

Filipino Americans are the second largest immigrant population and second largest Asian ethnic group in the U.S. Disparities in youth behavioral health problems and the receipt of mental health services among Filipino youth have been documented previously. However, few...

Targeted Therapies for the Treatment of Pediatric Non-Hodgkin Lymphomas: Present and Future.

Pharmaceuticals (Basel, Switzerland)

Sorge CE, McDaniel JK, Xavier AC.
PMID: 27213405
Pharmaceuticals (Basel). 2016 May 19;9(2). doi: 10.3390/ph9020028.

Pediatric Non-Hodgkin Lymphomas (NHL) are a diverse group of malignancies and as such treatment can vary based on the different biological characteristics of each malignancy. Significant advancements are being made in the treatment and outcomes of this group of...

Acute Bilateral Internal Carotid Occlusion from Embolization of Left Atrial Thrombus During Transesophageal Echocardiography: Case Report.

Journal of vascular and interventional neurology

Mahmood SS, Manjila S, Singh G, Xavier AR.
PMID: 27403219
J Vasc Interv Neurol. 2016 Jun;9(1):20-2.

BACKGROUND AND PURPOSE: Transesophageal echocardiography (TEE) is a relatively safe imaging modality used to visualize intracardiac thrombus.SUMMARY OF CASE: We report on a unique, fatal complication during TEE of embolization of a pre-existing "smoking" left atrial thrombus causing acute...

Clinical and radiographic comparison of indirect pulp treatment using light-cured calcium silicate and mineral trioxide aggregate in primary molars: A randomized clinical trial.

Contemporary clinical dentistry

Menon NP, Varma BR, Janardhanan S, Kumaran P, Xavier AM, Govinda BS.
PMID: 27994414
Contemp Clin Dent. 2016 Oct-Dec;7(4):475-480. doi: 10.4103/0976-237X.194109.

AIM: To clinically and radiographically evaluate the reparative dentin formation in indirect pulp treatment (IPT) using mineral trioxide aggregate (MTA) and light cured calcium silicate (TheraCal) in primary molars over a period of 6 months.MATERIALS AND METHODS: A clinical...

First human use of cyanoacrylate adhesive for treatment of saphenous vein incompetence.

Journal of vascular surgery. Venous and lymphatic disorders

Almeida JI, Javier JJ, Mackay E, Bautista C, Proebstle TM.
PMID: 26992340
J Vasc Surg Venous Lymphat Disord. 2013 Apr;1(2):174-80. doi: 10.1016/j.jvsv.2012.09.010. Epub 2012 Dec 22.

OBJECTIVE: The primary objective of this study was to assess the feasibility of an endovenous cyanoacrylate (CA) adhesive implant, delivered with a catheter-based administration system engineered with a nonstick surface, for the treatment of incompetent great saphenous veins (GSVs)....

Correction: The impact of anti-drug antibodies on drug concentrations and clinical outcomes in rheumatoid arthritis patients treated with adalimumab, etanercept, or infliximab: Results from a multinational, real-world clinical practice, non-interventional study.

PloS one

Moots RJ, Xavier RM, Mok CC, Rahman MU, Tsai WC, Al-Maini MH, Pavelka K, Mahgoub E, Kotak S, Korth-Bradley J, Pedersen R, Mele L, Shen Q, Vlahos B.
PMID: 28582423
PLoS One. 2017 Jun 05;12(6):e0179308. doi: 10.1371/journal.pone.0179308. eCollection 2017.

[This corrects the article DOI: 10.1371/journal.pone.0175207.].

The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes.

Cell host & microbe

Kostic AD, Gevers D, Siljander H, Vatanen T, Hyötyläinen T, Hämäläinen AM, Peet A, Tillmann V, Pöhö P, Mattila I, Lähdesmäki H, Franzosa EA, Vaarala O, de Goffau M, Harmsen H, Ilonen J, Virtanen SM, Clish CB, Orešič M, Huttenhower C, Knip M, Xavier RJ.
PMID: 25662751
Cell Host Microbe. 2015 Feb 11;17(2):260-73. doi: 10.1016/j.chom.2015.01.001. Epub 2015 Feb 05.

Colonization of the fetal and infant gut microbiome results in dynamic changes in diversity, which can impact disease susceptibility. To examine the relationship between human gut microbiome dynamics throughout infancy and type 1 diabetes (T1D), we examined a cohort...

Dosimetric evaluation of X-ray examinations of paranasal sinuses in pediatric patients.

Radiologia brasileira

Cantalupo Bde L, Xavier AC, da Silva CM, Andrade ME, de Barros VS, Khoury HJ.
PMID: 27141129
Radiol Bras. 2016 Mar-Apr;49(2):79-85. doi: 10.1590/0100-3984.2015.0081.

OBJECTIVE: To estimate the entrance surface air kerma (Ka,e) and air kerma in the region of radiosensitive organs in radiographs of pediatric paranasal sinuses.MATERIALS AND METHODS: Patient data and irradiation parameters were collected in examinations of the paranasal sinuses...

Acetabular Liner Dissociation following Total Hip Arthroplasty: A Rare but Serious Complication That May Be Easily Misinterpreted in the Emergency Department.

Case reports in emergency medicine

O'Neill CK, Napier RJ, Diamond OJ, O'Brien S, Beverland DE.
PMID: 26543652
Case Rep Emerg Med. 2015;2015:802753. doi: 10.1155/2015/802753. Epub 2015 Oct 12.

Acetabular liner dissociation is a rare complication of Total Hip Arthroplasty (THA) which requires urgent revision surgery. A case is presented in which the correct diagnosis was not appreciated on two separate Emergency Department attendances. The typical symptoms, signs,...

Blood-based lung cancer biomarkers identified through proteomic discovery in cancer tissues, cell lines and conditioned medium.

Clinical proteomics

Birse CE, Lagier RJ, FitzHugh W, Pass HI, Rom WN, Edell ES, Bungum AO, Maldonado F, Jett JR, Mesri M, Sult E, Joseloff E, Li A, Heidbrink J, Dhariwal G, Danis C, Tomic JL, Bruce RJ, Moore PA, He T, Lewis ME, Ruben SM.
PMID: 26279647
Clin Proteomics. 2015 Jul 16;12(1):18. doi: 10.1186/s12014-015-9090-9. eCollection 2015.

BACKGROUND: Support for early detection of lung cancer has emerged from the National Lung Screening Trial (NLST), in which low-dose computed tomography (LDCT) screening reduced lung cancer mortality by 20 % relative to chest x-ray. The US Preventive Services...

Showing 1 to 12 of 409 entries