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Recent advances in pruritus - what we have learned and where are we headed.

F1000 medicine reports

Yosipovitch G.
PMID: 20948846
F1000 Med Rep. 2010 May 24;2. doi: 10.3410/M2-39.

Chronic pruritus is an emerging health problem with a significant impact on quality of life. Recent advances in our understanding of newly discovered pathways and receptors for itch have been made. It is hoped that recent advancements will also...

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Yosipovitch G. Recent advances in pruritus - what we have learned and where are we headed. F1000 Med Rep. 2010;2doi: 10.3410/M2-39.
Yosipovitch, G. (2010). Recent advances in pruritus - what we have learned and where are we headed. F1000 medicine reports, 2. https://doi.org/10.3410/M2-39
Yosipovitch, Gil. "Recent advances in pruritus - what we have learned and where are we headed." F1000 medicine reports vol. 2 (2010). doi: https://doi.org/10.3410/M2-39
Yosipovitch G. Recent advances in pruritus - what we have learned and where are we headed. F1000 Med Rep. 2010 May 24;2. doi: 10.3410/M2-39. PMID: 20948846; PMCID: PMC2950052.
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The Development of a Patient-Reported Outcome Measure for Assessment of Genital Psoriasis Symptoms: The Genital Psoriasis Symptoms Scale (GPSS).

Dermatology and therapy

Gottlieb AB, Kirby B, Ryan C, Naegeli AN, Burge R, Potts Bleakman A, Anatchkova MD, Yosipovitch G.
PMID: 29204893
Dermatol Ther (Heidelb). 2018 Mar;8(1):45-56. doi: 10.1007/s13555-017-0213-2. Epub 2017 Dec 04.

INTRODUCTION: Patient-reported outcome measures (PROs) specific for genital psoriasis (GenPs) have not been described.METHODS: In this cross-sectional, qualitative study in patients with moderate-to-severe GenPs, we sought to develop a PRO useful for GenPs symptom assessment. A literature review was...

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Gottlieb AB, Kirby B, Ryan C, et al. The Development of a Patient-Reported Outcome Measure for Assessment of Genital Psoriasis Symptoms: The Genital Psoriasis Symptoms Scale (GPSS). Dermatol Ther (Heidelb). 2017;8(1):45-56doi: 10.1007/s13555-017-0213-2.
Gottlieb, A. B., Kirby, B., Ryan, C., Naegeli, A. N., Burge, R., Potts Bleakman, A., Anatchkova, M. D., & Yosipovitch, G. (2018). The Development of a Patient-Reported Outcome Measure for Assessment of Genital Psoriasis Symptoms: The Genital Psoriasis Symptoms Scale (GPSS). Dermatology and therapy, 8(1), 45-56. https://doi.org/10.1007/s13555-017-0213-2
Gottlieb, Alice B, et al. "The Development of a Patient-Reported Outcome Measure for Assessment of Genital Psoriasis Symptoms: The Genital Psoriasis Symptoms Scale (GPSS)." Dermatology and therapy vol. 8,1 (2018): 45-56. doi: https://doi.org/10.1007/s13555-017-0213-2
Gottlieb AB, Kirby B, Ryan C, Naegeli AN, Burge R, Potts Bleakman A, Anatchkova MD, Yosipovitch G. The Development of a Patient-Reported Outcome Measure for Assessment of Genital Psoriasis Symptoms: The Genital Psoriasis Symptoms Scale (GPSS). Dermatol Ther (Heidelb). 2018 Mar;8(1):45-56. doi: 10.1007/s13555-017-0213-2. Epub 2017 Dec 04. PMID: 29204893; PMCID: PMC5825318.
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Dupilumab Treatment Provides Sustained Improvements Over 2 Years in Symptoms and Quality of Life in Adults with Atopic Dermatitis.

Dermatology and therapy

Yosipovitch G, de Bruin-Weller M, Armstrong A, Wu JJ, Herranz P, Thaçi D, Delevry D, Bagousse GB, Zhang R, Shumel B, Rossi AB, Chao J.
PMID: 34714527
Dermatol Ther (Heidelb). 2021 Dec;11(6):2147-2157. doi: 10.1007/s13555-021-00630-9. Epub 2021 Oct 29.

INTRODUCTION: Atopic dermatitis (AD) can have a profound negative impact on the quality of life (QoL) of patients. We analyzed the long-term changes in AD symptoms, QoL, and patient assessment of treatment effect in adults with moderate-to-severe AD treated...

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Yosipovitch G, de Bruin-Weller M, Armstrong A, et al. Dupilumab Treatment Provides Sustained Improvements Over 2 Years in Symptoms and Quality of Life in Adults with Atopic Dermatitis. Dermatol Ther (Heidelb). 2021;11(6):2147-2157doi: 10.1007/s13555-021-00630-9.
Yosipovitch, G., de Bruin-Weller, M., Armstrong, A., Wu, J. J., Herranz, P., Thaçi, D., Delevry, D., Bagousse, G. B., Zhang, R., Shumel, B., Rossi, A. B., & Chao, J. (2021). Dupilumab Treatment Provides Sustained Improvements Over 2 Years in Symptoms and Quality of Life in Adults with Atopic Dermatitis. Dermatology and therapy, 11(6), 2147-2157. https://doi.org/10.1007/s13555-021-00630-9
Yosipovitch, Gil, et al. "Dupilumab Treatment Provides Sustained Improvements Over 2 Years in Symptoms and Quality of Life in Adults with Atopic Dermatitis." Dermatology and therapy vol. 11,6 (2021): 2147-2157. doi: https://doi.org/10.1007/s13555-021-00630-9
Yosipovitch G, de Bruin-Weller M, Armstrong A, Wu JJ, Herranz P, Thaçi D, Delevry D, Bagousse GB, Zhang R, Shumel B, Rossi AB, Chao J. Dupilumab Treatment Provides Sustained Improvements Over 2 Years in Symptoms and Quality of Life in Adults with Atopic Dermatitis. Dermatol Ther (Heidelb). 2021 Dec;11(6):2147-2157. doi: 10.1007/s13555-021-00630-9. Epub 2021 Oct 29. PMID: 34714527; PMCID: PMC8611171.
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Chronic itch in African Americans: an unmet need.

Archives of dermatological research

Ingrasci G, El-Kashlan N, Alexis A, Yosipovitch G.
PMID: 34129098
Arch Dermatol Res. 2021 Jun 15; doi: 10.1007/s00403-021-02255-6. Epub 2021 Jun 15.

Chronic pruritus carries a significant burden of disease and is associated with a negative impact on quality of life. African Americans are disproportionately burdened by chronic pruritic disorders, including but not limited to atopic dermatitis, prurigo nodularis, inflammatory scalp...

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Ingrasci G, El-Kashlan N, Alexis A, et al. Chronic itch in African Americans: an unmet need. Arch Dermatol Res. 2021;doi: 10.1007/s00403-021-02255-6.
Ingrasci, G., El-Kashlan, N., Alexis, A., & Yosipovitch, G. (2021). Chronic itch in African Americans: an unmet need. Archives of dermatological research, . https://doi.org/10.1007/s00403-021-02255-6
Ingrasci, Giuseppe, et al. "Chronic itch in African Americans: an unmet need." Archives of dermatological research vol. (2021). doi: https://doi.org/10.1007/s00403-021-02255-6
Ingrasci G, El-Kashlan N, Alexis A, Yosipovitch G. Chronic itch in African Americans: an unmet need. Arch Dermatol Res. 2021 Jun 15; doi: 10.1007/s00403-021-02255-6. Epub 2021 Jun 15. PMID: 34129098.
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The Functional Network Processing Acute Electrical Itch Stimuli in Humans.

Frontiers in physiology

Mochizuki H, Hernandez LE, Yosipovitch G, Sadato N, Kakigi R.
PMID: 31156452
Front Physiol. 2019 May 15;10:555. doi: 10.3389/fphys.2019.00555. eCollection 2019.

The posterior insula (pIns) is a major brain region that receives itch-related signals from the periphery and transfers these signals to broad areas in the brain. Previous brain imaging studies have successfully identified brain regions that respond to itch...

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Mochizuki H, Hernandez LE, Yosipovitch G, et al. The Functional Network Processing Acute Electrical Itch Stimuli in Humans. Front Physiol. 2019;10:555doi: 10.3389/fphys.2019.00555.
Mochizuki, H., Hernandez, L. E., Yosipovitch, G., Sadato, N., & Kakigi, R. (2019). The Functional Network Processing Acute Electrical Itch Stimuli in Humans. Frontiers in physiology, 10555. https://doi.org/10.3389/fphys.2019.00555
Mochizuki, Hideki, et al. "The Functional Network Processing Acute Electrical Itch Stimuli in Humans." Frontiers in physiology vol. 10 (2019): 555. doi: https://doi.org/10.3389/fphys.2019.00555
Mochizuki H, Hernandez LE, Yosipovitch G, Sadato N, Kakigi R. The Functional Network Processing Acute Electrical Itch Stimuli in Humans. Front Physiol. 2019 May 15;10:555. doi: 10.3389/fphys.2019.00555. eCollection 2019. PMID: 31156452; PMCID: PMC6529842.
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The contribution of itch and skin severity improvements to the Dermatology Life Quality Index in patients with atopic dermatitis in baricitinib phase 3 trials.

The British journal of dermatology

Yosipovitch G, Papp K, Forman S, Han G, Waibel J, Rueda MJ, Sun L, Chen YF, Goldblum O, Pierce E, Silverberg JI.
PMID: 35041213
Br J Dermatol. 2022 Jan 18; doi: 10.1111/bjd.21015. Epub 2022 Jan 18.

No abstract available.

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Yosipovitch G, Papp K, Forman S, et al. The contribution of itch and skin severity improvements to the Dermatology Life Quality Index in patients with atopic dermatitis in baricitinib phase 3 trials. Br J Dermatol. 2022;doi: 10.1111/bjd.21015.
Yosipovitch, G., Papp, K., Forman, S., Han, G., Waibel, J., Rueda, M. J., Sun, L., Chen, Y. F., Goldblum, O., Pierce, E., & Silverberg, J. I. (2022). The contribution of itch and skin severity improvements to the Dermatology Life Quality Index in patients with atopic dermatitis in baricitinib phase 3 trials. The British journal of dermatology, . https://doi.org/10.1111/bjd.21015
Yosipovitch, Gil, et al. "The contribution of itch and skin severity improvements to the Dermatology Life Quality Index in patients with atopic dermatitis in baricitinib phase 3 trials." The British journal of dermatology vol. (2022). doi: https://doi.org/10.1111/bjd.21015
Yosipovitch G, Papp K, Forman S, Han G, Waibel J, Rueda MJ, Sun L, Chen YF, Goldblum O, Pierce E, Silverberg JI. The contribution of itch and skin severity improvements to the Dermatology Life Quality Index in patients with atopic dermatitis in baricitinib phase 3 trials. Br J Dermatol. 2022 Jan 18; doi: 10.1111/bjd.21015. Epub 2022 Jan 18. PMID: 35041213.
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The association of chronic pruritus with patients' quality of life: A cross-sectional study.

Journal of the American Academy of Dermatology

Lipman ZM, Yap QV, Rosen J, Nattkemper L, Yosipovitch G.
PMID: 34626734
J Am Acad Dermatol. 2021 Oct 06; doi: 10.1016/j.jaad.2021.09.062. Epub 2021 Oct 06.

No abstract available.

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Lipman ZM, Yap QV, Rosen J, et al. The association of chronic pruritus with patients' quality of life: A cross-sectional study. J Am Acad Dermatol. 2021;doi: 10.1016/j.jaad.2021.09.062.
Lipman, Z. M., Yap, Q. V., Rosen, J., Nattkemper, L., & Yosipovitch, G. (2021). The association of chronic pruritus with patients' quality of life: A cross-sectional study. Journal of the American Academy of Dermatology, . https://doi.org/10.1016/j.jaad.2021.09.062
Lipman, Zoe Morgan, et al. "The association of chronic pruritus with patients' quality of life: A cross-sectional study." Journal of the American Academy of Dermatology vol. (2021). doi: https://doi.org/10.1016/j.jaad.2021.09.062
Lipman ZM, Yap QV, Rosen J, Nattkemper L, Yosipovitch G. The association of chronic pruritus with patients' quality of life: A cross-sectional study. J Am Acad Dermatol. 2021 Oct 06; doi: 10.1016/j.jaad.2021.09.062. Epub 2021 Oct 06. PMID: 34626734.
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Current Clinical Options for the Management of Itch in Atopic Dermatitis.

Clinical, cosmetic and investigational dermatology

Lipman ZM, Labib A, Yosipovitch G.
PMID: 34377004
Clin Cosmet Investig Dermatol. 2021 Aug 03;14:959-969. doi: 10.2147/CCID.S289716. eCollection 2021.

Pruritus is the most burdensome and prevalent symptom in patients suffering from atopic dermatitis. Treating atopic itch has historically been a challenge due to multiple underlying mechanisms within its pathogenesis and an incomplete understanding of them. In recent years,...

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Lipman ZM, Labib A, Yosipovitch G. Current Clinical Options for the Management of Itch in Atopic Dermatitis. Clin Cosmet Investig Dermatol. 2021;14:959-969doi: 10.2147/CCID.S289716.
Lipman, Z. M., Labib, A., & Yosipovitch, G. (2021). Current Clinical Options for the Management of Itch in Atopic Dermatitis. Clinical, cosmetic and investigational dermatology, 14959-969. https://doi.org/10.2147/CCID.S289716
Lipman, Zoe M, et al. "Current Clinical Options for the Management of Itch in Atopic Dermatitis." Clinical, cosmetic and investigational dermatology vol. 14 (2021): 959-969. doi: https://doi.org/10.2147/CCID.S289716
Lipman ZM, Labib A, Yosipovitch G. Current Clinical Options for the Management of Itch in Atopic Dermatitis. Clin Cosmet Investig Dermatol. 2021 Aug 03;14:959-969. doi: 10.2147/CCID.S289716. eCollection 2021. PMID: 34377004; PMCID: PMC8349193.
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Clinical management of chronic kidney disease-associated pruritus: current treatment options and future approaches.

Clinical kidney journal

Lipman ZM, Paramasivam V, Yosipovitch G, Germain MJ.
PMID: 34987779
Clin Kidney J. 2021 Oct 14;14:i16-i22. doi: 10.1093/ckj/sfab167. eCollection 2021 Dec.

Chronic kidney disease (CKD)-associated pruritus (CKD-aP) is an underdiagnosed yet severely distressing condition that impacts 60% of patients on dialysis and many nondialysis patients with Stages 3-5 CKD. However, despite its high prevalence, there are currently limited treatment options...

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Lipman ZM, Paramasivam V, Yosipovitch G, et al. Clinical management of chronic kidney disease-associated pruritus: current treatment options and future approaches. Clin Kidney J. 2021;14:i16-i22doi: 10.1093/ckj/sfab167.
Lipman, Z. M., Paramasivam, V., Yosipovitch, G., & Germain, M. J. (2021). Clinical management of chronic kidney disease-associated pruritus: current treatment options and future approaches. Clinical kidney journal, 14i16-i22. https://doi.org/10.1093/ckj/sfab167
Lipman, Zoe M, et al. "Clinical management of chronic kidney disease-associated pruritus: current treatment options and future approaches." Clinical kidney journal vol. 14 (2021): i16-i22. doi: https://doi.org/10.1093/ckj/sfab167
Lipman ZM, Paramasivam V, Yosipovitch G, Germain MJ. Clinical management of chronic kidney disease-associated pruritus: current treatment options and future approaches. Clin Kidney J. 2021 Oct 14;14:i16-i22. doi: 10.1093/ckj/sfab167. eCollection 2021 Dec. PMID: 34987779; PMCID: PMC8702820.
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Pruritus as a Distinctive Feature of Type 2 Inflammation.

Vaccines

Garcovich S, Maurelli M, Gisondi P, Peris K, Yosipovitch G, Girolomoni G.
PMID: 33807098
Vaccines (Basel). 2021 Mar 23;9(3). doi: 10.3390/vaccines9030303.

Pruritus is a common symptom of several skin diseases, both inflammatory and neoplastic. Pruritus might have a tremendous impact on patients' quality of life and strongly interfere with sleep, social, and work activities. We review the role of type-2...

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Garcovich S, Maurelli M, Gisondi P, et al. Pruritus as a Distinctive Feature of Type 2 Inflammation. Vaccines (Basel). 2021;9(3)doi: 10.3390/vaccines9030303.
Garcovich, S., Maurelli, M., Gisondi, P., Peris, K., Yosipovitch, G., & Girolomoni, G. (2021). Pruritus as a Distinctive Feature of Type 2 Inflammation. Vaccines, 9(3), . https://doi.org/10.3390/vaccines9030303
Garcovich, Simone, et al. "Pruritus as a Distinctive Feature of Type 2 Inflammation." Vaccines vol. 9,3 (2021). doi: https://doi.org/10.3390/vaccines9030303
Garcovich S, Maurelli M, Gisondi P, Peris K, Yosipovitch G, Girolomoni G. Pruritus as a Distinctive Feature of Type 2 Inflammation. Vaccines (Basel). 2021 Mar 23;9(3). doi: 10.3390/vaccines9030303. PMID: 33807098; PMCID: PMC8005108.
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Brain Processing of Contagious Itch in Patients with Atopic Dermatitis.

Frontiers in psychology

Schut C, Mochizuki H, Grossman SK, Lin AC, Conklin CJ, Mohamed FB, Gieler U, Kupfer J, Yosipovitch G.
PMID: 28790959
Front Psychol. 2017 Jul 25;8:1267. doi: 10.3389/fpsyg.2017.01267. eCollection 2017.

Several studies show that itch and scratching cannot only be induced by pruritogens like histamine or cowhage, but also by the presentation of certain (audio-) visual stimuli like pictures on crawling insects or videos showing other people scratching. This...

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Schut C, Mochizuki H, Grossman SK, et al. Brain Processing of Contagious Itch in Patients with Atopic Dermatitis. Front Psychol. 2017;8:1267doi: 10.3389/fpsyg.2017.01267.
Schut, C., Mochizuki, H., Grossman, S. K., Lin, A. C., Conklin, C. J., Mohamed, F. B., Gieler, U., Kupfer, J., & Yosipovitch, G. (2017). Brain Processing of Contagious Itch in Patients with Atopic Dermatitis. Frontiers in psychology, 81267. https://doi.org/10.3389/fpsyg.2017.01267
Schut, Christina, et al. "Brain Processing of Contagious Itch in Patients with Atopic Dermatitis." Frontiers in psychology vol. 8 (2017): 1267. doi: https://doi.org/10.3389/fpsyg.2017.01267
Schut C, Mochizuki H, Grossman SK, Lin AC, Conklin CJ, Mohamed FB, Gieler U, Kupfer J, Yosipovitch G. Brain Processing of Contagious Itch in Patients with Atopic Dermatitis. Front Psychol. 2017 Jul 25;8:1267. doi: 10.3389/fpsyg.2017.01267. eCollection 2017. PMID: 28790959; PMCID: PMC5524890.
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Management of Itch in the Elderly: A Review.

Dermatology and therapy

Fourzali KM, Yosipovitch G.
PMID: 31549284
Dermatol Ther (Heidelb). 2019 Dec;9(4):639-653. doi: 10.1007/s13555-019-00326-1. Epub 2019 Sep 23.

Chronic itch is common in the elderly patient and may be caused by a variety of known dermatologic and non-dermatologic conditions and can have a significant effect on quality of life. Age-related changes in barrier function, immunosenescence, and neuronal...

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Fourzali KM, Yosipovitch G. Management of Itch in the Elderly: A Review. Dermatol Ther (Heidelb). 2019;9(4):639-653doi: 10.1007/s13555-019-00326-1.
Fourzali, K. M., & Yosipovitch, G. (2019). Management of Itch in the Elderly: A Review. Dermatology and therapy, 9(4), 639-653. https://doi.org/10.1007/s13555-019-00326-1
Fourzali, Kayla M, and Yosipovitch, Gil. "Management of Itch in the Elderly: A Review." Dermatology and therapy vol. 9,4 (2019): 639-653. doi: https://doi.org/10.1007/s13555-019-00326-1
Fourzali KM, Yosipovitch G. Management of Itch in the Elderly: A Review. Dermatol Ther (Heidelb). 2019 Dec;9(4):639-653. doi: 10.1007/s13555-019-00326-1. Epub 2019 Sep 23. PMID: 31549284; PMCID: PMC6828892.
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Showing 1 to 12 of 58 entries