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Showing 1 to 12 of 9016 entries
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Inhibition of RhoA/Rho-kinase pathway suppresses the expression of extracellular matrix induced by CTGF or TGF-β in ARPE-19.

International journal of ophthalmology

Zhu J, Nguyen D, Ouyang H, Zhang XH, Chen XM, Zhang K.
PMID: 23550216
Int J Ophthalmol. 2013;6(1):8-14. doi: 10.3980/j.issn.2222-3959.2013.01.02. Epub 2013 Feb 18.

AIM: To investigate the role of Rho-associated protein kinase (ROCK) inhibitor, Y27632, in mediating the production of extracellular matrix (ECM) components including fibronectin, matrix metallo-proteinase-2 (MMP-2) and type I collagen as induced by connective tissue growth factor (CTGF) or...

MutS-mediated enrichment of mutated DNA produced by directed evolution in vitro.

World journal of microbiology & biotechnology

Zhong T, Zhou Y, Bi L, Zhang XE.
PMID: 25187136
World J Microbiol Biotechnol. 2011 Jun;27(6):1367-72. doi: 10.1007/s11274-010-0587-0. Epub 2010 Oct 10.

Directed evolution in vitro is a powerful tool in the study and design of protein function. However, screening the desired mutants is a difficult task. To facilitate the screening, a method is proposed to eliminate wild type sequences and...

Effects of 530 nm monochromatic light on basic fibroblast growth factor and transforming growth factor-β1 expression in Müller cells.

International journal of ophthalmology

Fu XY, Zhang XF, Xia W, Zhong L, Wang YM, Sun ZT, Xia J.
PMID: 26558199
Int J Ophthalmol. 2015 Oct 18;8(5):904-9. doi: 10.3980/j.issn.2222-3959.2015.05.09. eCollection 2015.

AIM: To expose rat retinal Müller cells to 530 nm monochromatic light and investigate the influence of varying light illumination times on basic fibroblast growth factor (bFGF) and transforming growth factor-β1 (TGF-β1) expression.METHODS: Three groups of rat retinal Müller...

Synthesis of dibenzo[c,e]oxepin-5(7H)-ones from benzyl thioethers and carboxylic acids: rhodium-catalyzed double C-H activation controlled by different directing groups.

Angewandte Chemie (International ed. in English)

Zhang XS, Zhang YF, Li ZW, Luo FX, Shi ZJ.
PMID: 25757707
Angew Chem Int Ed Engl. 2015 Apr 27;54(18):5478-82. doi: 10.1002/anie.201500486. Epub 2015 Mar 10.

A rhodium(III)-catalyzed cross-coupling of benzyl thioethers and aryl carboxylic acids through the two directing groups is reported. Useful structures with diverse substituents were efficiently synthesized in one step with the cleavage of four bonds (CH, CS, OH) and the...

A Critical Review of Theories and Measures of Ethics-Related Leadership.

New directions for student leadership

Zhu W, Zheng X, Riggio RE, Zhang X.
PMID: 26894906
New Dir Stud Leadersh. 2015;2015(146):81-96. doi: 10.1002/yd.20137.

This chapter reviews the different theoretical perspectives and measurements of ethics-related leadership models, including ethical leadership, transformational leadership, authentic leadership, servant leadership, spiritual leadership, and a virtues-based approach to leadership ethics. The similarities and differences among these theoretical models...

The loss-of-function of DNA methyltransferase 1 by siRNA impairs the growth of non-small cell lung cancer with alleviated side effects via reactivation of RASSF1A and APC .

Oncotarget

Lai Q, Xu YH, Chen Q, Tang L, Li AG, Zhang LF, Zhang CF, Song JF, Du ZZ.
PMID: 28938637
Oncotarget. 2017 Jul 26;8(35):59301-59311. doi: 10.18632/oncotarget.19573. eCollection 2017 Aug 29.

Hypermethylation of tumor suppressor genes (TSGs) promoters by DNA methyltransferase (DNMT) can be observed in almost all cancers which represent a hallmark of carcinogenesis, including lung cancer. DNMT inhibitors (e.g.5-Aza-CR/CdR) reactivate TSGs to exert anti-cancer activity and have been...

Reply by the Authors.

Urology

Han H, Zhang XD, Tian L.
PMID: 26966040
Urology. 2016 Jun;92:140-1. doi: 10.1016/j.urology.2016.02.038. Epub 2016 Mar 07.

No abstract available.

An informatics guided classification of miscible and immiscible binary alloy systems.

Scientific reports

Zhang RF, Kong XF, Wang HT, Zhang SH, Legut D, Sheng SH, Srinivasan S, Rajan K, Germann TC.
PMID: 28851941
Sci Rep. 2017 Aug 29;7(1):9577. doi: 10.1038/s41598-017-09704-1.

The classification of miscible and immiscible systems of binary alloys plays a critical role in the design of multicomponent alloys. By mining data from hundreds of experimental phase diagrams, and thousands of thermodynamic data sets from experiments and high-throughput...

[Further understanding of membranoproliferative glomerulonephritis].

Zhonghua er ke za zhi = Chinese journal of pediatrics

Wu W, Yang X, Zhang RF.
PMID: 28881523
Zhonghua Er Ke Za Zhi. 2017 Sep 02;55(9):711-713. doi: 10.3760/cma.j.issn.0578-1310.2017.09.020.

No abstract available.

Consensus and conflict in invasive micropapillary carcinoma: a case report and review of the literature.

Journal of gastrointestinal oncology

Lei L, Zhang H, Zhang XB, Lonser R, Thompson K, Raza A.
PMID: 27034813
J Gastrointest Oncol. 2016 Apr;7:S55-61. doi: 10.3978/j.issn.2078-6891.2015.029.

Invasive micropapillary carcinoma (IMPC) is an aggressive histologic subtype of adenocarcinoma that has been gaining increased attention over the past twenty years. It is important to recognize IMPC due to its strong association with early lymphovascular invasion (LVI), high...

Supramolecular Interfacial Polymerization: A Controllable Method of Fabricating Supramolecular Polymeric Materials.

Angewandte Chemie (International ed. in English)

Qin B, Zhang S, Song Q, Huang Z, Xu JF, Zhang X.
PMID: 28480605
Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7639-7643. doi: 10.1002/anie.201703572. Epub 2017 May 24.

A new method of supramolecular polymerization at the water-oil interface is developed. As a demonstration, an oil-soluble supramonomer containing two thiol end groups linked by two ureidopyrimidinone units and a water-soluble monomer bearing two maleimide end groups are employed....

Antibiotic-loaded MoS.

Nanotechnology

Zhang X, Zhang W, Liu L, Yang M, Huang L, Chen K, Wang R, Yang B, Zhang D, Wang J.
PMID: 28480869
Nanotechnology. 2017 May 08;28(22):225101. doi: 10.1088/1361-6528/aa6c9b. Epub 2017 May 08.

The emergence of antibiotic resistance has resulted in increasing difficulty in treating clinical infections associated with biofilm formation, one of the key processes in turn contributing to enhanced antibiotic resistance. With the rapid development of nanotechnology, a new way...

Showing 1 to 12 of 9016 entries