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Showing 1 to 12 of 9006 entries
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Inhibition of RhoA/Rho-kinase pathway suppresses the expression of extracellular matrix induced by CTGF or TGF-β in ARPE-19.

International journal of ophthalmology

Zhu J, Nguyen D, Ouyang H, Zhang XH, Chen XM, Zhang K.
PMID: 23550216
Int J Ophthalmol. 2013;6(1):8-14. doi: 10.3980/j.issn.2222-3959.2013.01.02. Epub 2013 Feb 18.

AIM: To investigate the role of Rho-associated protein kinase (ROCK) inhibitor, Y27632, in mediating the production of extracellular matrix (ECM) components including fibronectin, matrix metallo-proteinase-2 (MMP-2) and type I collagen as induced by connective tissue growth factor (CTGF) or...

MutS-mediated enrichment of mutated DNA produced by directed evolution in vitro.

World journal of microbiology & biotechnology

Zhong T, Zhou Y, Bi L, Zhang XE.
PMID: 25187136
World J Microbiol Biotechnol. 2011 Jun;27(6):1367-72. doi: 10.1007/s11274-010-0587-0. Epub 2010 Oct 10.

Directed evolution in vitro is a powerful tool in the study and design of protein function. However, screening the desired mutants is a difficult task. To facilitate the screening, a method is proposed to eliminate wild type sequences and...

Effects of 530 nm monochromatic light on basic fibroblast growth factor and transforming growth factor-β1 expression in Müller cells.

International journal of ophthalmology

Fu XY, Zhang XF, Xia W, Zhong L, Wang YM, Sun ZT, Xia J.
PMID: 26558199
Int J Ophthalmol. 2015 Oct 18;8(5):904-9. doi: 10.3980/j.issn.2222-3959.2015.05.09. eCollection 2015.

AIM: To expose rat retinal Müller cells to 530 nm monochromatic light and investigate the influence of varying light illumination times on basic fibroblast growth factor (bFGF) and transforming growth factor-β1 (TGF-β1) expression.METHODS: Three groups of rat retinal Müller...

Validation of the European Organization for Research and Treatment of Cancer cervical cancer module for Chinese patients with cervical cancer.

Patient preference and adherence

Hua CH, Guo HM, Guan XL, Kong FJ, Hou RJ, Zhang XY, Li SR.
PMID: 24204125
Patient Prefer Adherence. 2013 Oct 17;7:1061-6. doi: 10.2147/PPA.S52498. eCollection 2013.

PURPOSE: The aim of our study was to assess, for the first time, the validity, reliability, and acceptability of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life questionnaire (QLQ) cervical cancer module (CX24) in...

Clinical effectiveness analysis of dextran 40 plus dexamethasone on the prevention of fat embolism syndrome.

International journal of clinical and experimental medicine

Liu XM, Huang JC, Wang GD, Lan SH, Wang HS, Pan CW, Zhang JP, Cai XH.
PMID: 25232433
Int J Clin Exp Med. 2014 Aug 15;7(8):2343-6. eCollection 2014.

This study aims to investigate the clinical efficacy of Dextran 40 plus dexamethasone on the prevention of fat embolism syndrome (FES) in high-risk patients with long bone shaft fractures. According to the different preventive medication, a total of 1837...

Synthesis of dibenzo[c,e]oxepin-5(7H)-ones from benzyl thioethers and carboxylic acids: rhodium-catalyzed double C-H activation controlled by different directing groups.

Angewandte Chemie (International ed. in English)

Zhang XS, Zhang YF, Li ZW, Luo FX, Shi ZJ.
PMID: 25757707
Angew Chem Int Ed Engl. 2015 Apr 27;54(18):5478-82. doi: 10.1002/anie.201500486. Epub 2015 Mar 10.

A rhodium(III)-catalyzed cross-coupling of benzyl thioethers and aryl carboxylic acids through the two directing groups is reported. Useful structures with diverse substituents were efficiently synthesized in one step with the cleavage of four bonds (CH, CS, OH) and the...

Rapid 3D µ-printing of polymer optical whispering-gallery mode resonators.

Optics express

Wu J, Guo X, Zhang AP, Tam HY.
PMID: 26698452
Opt Express. 2015 Nov 16;23(23):29708-14. doi: 10.1364/OE.23.029708.

A novel microfabrication method for rapid printing of polymer optical whispering-gallery mode (WGM) resonators is presented. A 3D micro-printing technology based on high-speed optical spatial modulator (SLM) and high-power UV light source is developed to fabricate suspended-disk WGM resonator...

A Critical Review of Theories and Measures of Ethics-Related Leadership.

New directions for student leadership

Zhu W, Zheng X, Riggio RE, Zhang X.
PMID: 26894906
New Dir Stud Leadersh. 2015;2015(146):81-96. doi: 10.1002/yd.20137.

This chapter reviews the different theoretical perspectives and measurements of ethics-related leadership models, including ethical leadership, transformational leadership, authentic leadership, servant leadership, spiritual leadership, and a virtues-based approach to leadership ethics. The similarities and differences among these theoretical models...

Reply by the Authors.

Urology

Han H, Zhang XD, Tian L.
PMID: 26966040
Urology. 2016 Jun;92:140-1. doi: 10.1016/j.urology.2016.02.038. Epub 2016 Mar 07.

No abstract available.

Chromobox homolog 2 protein: A novel biomarker for predicting prognosis and Taxol sensitivity in patients with breast cancer.

Oncology letters

Chen WY, Zhang XY, Liu T, Liu Y, Zhao YS, Pang D.
PMID: 28454227
Oncol Lett. 2017 Mar;13(3):1149-1156. doi: 10.3892/ol.2016.5529. Epub 2016 Dec 23.

Polycomb group (PcG) complexes modify histones to silence tumor suppressor genes, which exhibit an important function in tumorigenesis and progression. The chromobox (Cbx) protein family is a critical component of PcG-mediated repression. Cbx2, a member of the Cbx protein...

Consensus and conflict in invasive micropapillary carcinoma: a case report and review of the literature.

Journal of gastrointestinal oncology

Lei L, Zhang H, Zhang XB, Lonser R, Thompson K, Raza A.
PMID: 27034813
J Gastrointest Oncol. 2016 Apr;7:S55-61. doi: 10.3978/j.issn.2078-6891.2015.029.

Invasive micropapillary carcinoma (IMPC) is an aggressive histologic subtype of adenocarcinoma that has been gaining increased attention over the past twenty years. It is important to recognize IMPC due to its strong association with early lymphovascular invasion (LVI), high...

Supramolecular Interfacial Polymerization: A Controllable Method of Fabricating Supramolecular Polymeric Materials.

Angewandte Chemie (International ed. in English)

Qin B, Zhang S, Song Q, Huang Z, Xu JF, Zhang X.
PMID: 28480605
Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7639-7643. doi: 10.1002/anie.201703572. Epub 2017 May 24.

A new method of supramolecular polymerization at the water-oil interface is developed. As a demonstration, an oil-soluble supramonomer containing two thiol end groups linked by two ureidopyrimidinone units and a water-soluble monomer bearing two maleimide end groups are employed....

Showing 1 to 12 of 9006 entries