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Showing 1 to 12 of 9450 entries
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Inhibition of RhoA/Rho-kinase pathway suppresses the expression of extracellular matrix induced by CTGF or TGF-β in ARPE-19.

International journal of ophthalmology

Zhu J, Nguyen D, Ouyang H, Zhang XH, Chen XM, Zhang K.
PMID: 23550216
Int J Ophthalmol. 2013;6(1):8-14. doi: 10.3980/j.issn.2222-3959.2013.01.02. Epub 2013 Feb 18.

AIM: To investigate the role of Rho-associated protein kinase (ROCK) inhibitor, Y27632, in mediating the production of extracellular matrix (ECM) components including fibronectin, matrix metallo-proteinase-2 (MMP-2) and type I collagen as induced by connective tissue growth factor (CTGF) or...

MutS-mediated enrichment of mutated DNA produced by directed evolution in vitro.

World journal of microbiology & biotechnology

Zhong T, Zhou Y, Bi L, Zhang XE.
PMID: 25187136
World J Microbiol Biotechnol. 2011 Jun;27(6):1367-72. doi: 10.1007/s11274-010-0587-0. Epub 2010 Oct 10.

Directed evolution in vitro is a powerful tool in the study and design of protein function. However, screening the desired mutants is a difficult task. To facilitate the screening, a method is proposed to eliminate wild type sequences and...

Effects of 530 nm monochromatic light on basic fibroblast growth factor and transforming growth factor-β1 expression in Müller cells.

International journal of ophthalmology

Fu XY, Zhang XF, Xia W, Zhong L, Wang YM, Sun ZT, Xia J.
PMID: 26558199
Int J Ophthalmol. 2015 Oct 18;8(5):904-9. doi: 10.3980/j.issn.2222-3959.2015.05.09. eCollection 2015.

AIM: To expose rat retinal Müller cells to 530 nm monochromatic light and investigate the influence of varying light illumination times on basic fibroblast growth factor (bFGF) and transforming growth factor-β1 (TGF-β1) expression.METHODS: Three groups of rat retinal Müller...

Validation of the European Organization for Research and Treatment of Cancer cervical cancer module for Chinese patients with cervical cancer.

Patient preference and adherence

Hua CH, Guo HM, Guan XL, Kong FJ, Hou RJ, Zhang XY, Li SR.
PMID: 24204125
Patient Prefer Adherence. 2013 Oct 17;7:1061-6. doi: 10.2147/PPA.S52498. eCollection 2013.

PURPOSE: The aim of our study was to assess, for the first time, the validity, reliability, and acceptability of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life questionnaire (QLQ) cervical cancer module (CX24) in...

Synthesis of dibenzo[c,e]oxepin-5(7H)-ones from benzyl thioethers and carboxylic acids: rhodium-catalyzed double C-H activation controlled by different directing groups.

Angewandte Chemie (International ed. in English)

Zhang XS, Zhang YF, Li ZW, Luo FX, Shi ZJ.
PMID: 25757707
Angew Chem Int Ed Engl. 2015 Apr 27;54(18):5478-82. doi: 10.1002/anie.201500486. Epub 2015 Mar 10.

A rhodium(III)-catalyzed cross-coupling of benzyl thioethers and aryl carboxylic acids through the two directing groups is reported. Useful structures with diverse substituents were efficiently synthesized in one step with the cleavage of four bonds (CH, CS, OH) and the...

A Critical Review of Theories and Measures of Ethics-Related Leadership.

New directions for student leadership

Zhu W, Zheng X, Riggio RE, Zhang X.
PMID: 26894906
New Dir Stud Leadersh. 2015;2015(146):81-96. doi: 10.1002/yd.20137.

This chapter reviews the different theoretical perspectives and measurements of ethics-related leadership models, including ethical leadership, transformational leadership, authentic leadership, servant leadership, spiritual leadership, and a virtues-based approach to leadership ethics. The similarities and differences among these theoretical models...

Association of genotypes of rs671 within.

Cancer biology & medicine

Zhang LQ, Song X, Zhao XK, Huang J, Zhang P, Wang LW, Meng H, Ku JW, Kong GQ, Jiang T, Li XM, Lv XL, Ma T, Yuan G, Wu MJ, Hu SJ, Lv S, Zhang TJ, Ji LF, Fan ZM, Wang NC, Zhang YW, Zhou FY, Wang LD.
PMID: 28443204
Cancer Biol Med. 2017 Feb;14(1):60-65. doi: 10.20892/j.issn.2095-3941.2016.0089.

OBJECTIVE: : This study aimed to determine if gastric cardia adenocarcinoma (GCA) risk was associated with the lys (A or *2) allele at the rs671 (glu504lys) polymorphism within the aldehyde dehydrogenase 2 (METHODS: : We designed a case-control study...

Reply by the Authors.

Urology

Han H, Zhang XD, Tian L.
PMID: 26966040
Urology. 2016 Jun;92:140-1. doi: 10.1016/j.urology.2016.02.038. Epub 2016 Mar 07.

No abstract available.

Chromobox homolog 2 protein: A novel biomarker for predicting prognosis and Taxol sensitivity in patients with breast cancer.

Oncology letters

Chen WY, Zhang XY, Liu T, Liu Y, Zhao YS, Pang D.
PMID: 28454227
Oncol Lett. 2017 Mar;13(3):1149-1156. doi: 10.3892/ol.2016.5529. Epub 2016 Dec 23.

Polycomb group (PcG) complexes modify histones to silence tumor suppressor genes, which exhibit an important function in tumorigenesis and progression. The chromobox (Cbx) protein family is a critical component of PcG-mediated repression. Cbx2, a member of the Cbx protein...

Consensus and conflict in invasive micropapillary carcinoma: a case report and review of the literature.

Journal of gastrointestinal oncology

Lei L, Zhang H, Zhang XB, Lonser R, Thompson K, Raza A.
PMID: 27034813
J Gastrointest Oncol. 2016 Apr;7:S55-61. doi: 10.3978/j.issn.2078-6891.2015.029.

Invasive micropapillary carcinoma (IMPC) is an aggressive histologic subtype of adenocarcinoma that has been gaining increased attention over the past twenty years. It is important to recognize IMPC due to its strong association with early lymphovascular invasion (LVI), high...

De novo transcriptome assembly databases for the butterfly orchid Phalaenopsis equestris.

Scientific data

Niu SC, Xu Q, Zhang GQ, Zhang YQ, Tsai WC, Hsu JL, Liang CK, Luo YB, Liu ZJ.
PMID: 27673730
Sci Data. 2016 Sep 27;3:160083. doi: 10.1038/sdata.2016.83.

Orchids are renowned for their spectacular flowers and ecological adaptations. After the sequencing of the genome of the tropical epiphytic orchid Phalaenopsis equestris, we combined Illumina HiSeq2000 for RNA-Seq and Trinity for de novo assembly to characterize the transcriptomes...

A Chinese Pane-Like 2D Metal-Organic Framework Showing Magnetic Relaxation and Luminescence Dual-Functions.

Scientific reports

Liu CM, Zhang DQ, Hao X, Zhu DB.
PMID: 28894130
Sci Rep. 2017 Sep 11;7(1):11156. doi: 10.1038/s41598-017-11006-5.

The discovery of graphene kicked off the curtain of atom-type two-dimensional (2D) materials. Layered metal-organic frameworks (MOFs) as parallel molecule-based 2D materials are more designable and more diverse, and magnetism may be induced by their metal ion nodes. However,...

Showing 1 to 12 of 9450 entries