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Showing 1 to 12 of 14165 entries
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Underrepresentation of active histone modification marks in evolutionarily young genes

Science and underrepresentation

Zhang YE.
GSID: b-KmooQ1kdEJ
D Yu, W Shi, YE Zhang - Insect science, 2017 - Wiley Online Library

It is known that evolutionarily new genes can rapidly evolve essential roles in fundamental biological processes. Nevertheless, the underlying molecular mechanism of how they acquire …

A survey on evaluation methods for image segmentation

evaluation

Zhang YJ.
GSID: OlxFXjDXilUJ
YJ Zhang - Pattern recognition, 1996 - Elsevier

… Abstract--This paper studies different methods proposed so far for segmentation evaluation. Most methods can be classified into three … evaluation abilities. In addition, some special methods are also discussed. This study is helpful for an appropriate use of...

Quantitative study of compositional uniformity and interfacial strain in InAs/InAs1-xSbx type-II superlattices

Minority STEM

Lu J, Smith DJ, Zhang YH.
GSID: BDMElJhVUDgJ
J Lu, XM Shen, YH Zhang, DJ Smith - Microscopy and Microanalysis, 2014 - cambridge.org

… , suffers from short minority carrier lifetime possibly due to … has demonstrated significantly improved minority carrier lifetime [… and aberration-corrected STEM (AC-STEM, JEOL ARM200F) …

A network biology approach evaluating the anticancer effects of bortezomib identifies SPARC as a therapeutic target in adult T-cell leukemia cells.

Advances and applications in bioinformatics and chemistry : AABC

Ohyashiki JH, Hamamura R, Kobayashi C, Zhang Y, Ohyashiki K.
PMID: 21918608
Adv Appl Bioinform Chem. 2008;1:85-98. doi: 10.2147/aabc.s4133. Epub 2008 Oct 30.

There is a need to identify the regulatory gene interaction of anticancer drugs on target cancer cells. Whole genome expression profiling offers promise in this regard, but can be complicated by the challenge of identifying the genes affected by...

Weakening density dependence from climate change and agricultural intensification triggers pest outbreaks: a 37-year observation of cotton bollworms.

Ecology and evolution

Ouyang F, Hui C, Ge S, Men XY, Zhao ZH, Shi PJ, Zhang YS, Li BL.
PMID: 25535553
Ecol Evol. 2014 Sep;4(17):3362-74. doi: 10.1002/ece3.1190. Epub 2014 Aug 12.

Understanding drivers of population fluctuation, especially for agricultural pests, is central to the provision of agro-ecosystem services. Here, we examine the role of endogenous density dependence and exogenous factors of climate and human activity in regulating the 37-year population...

Correction: regeneration of Solanum nigrum by somatic embryogenesis, involving frog egg-like body, a novel structure.

PloS one

Xu K, Chang Y, Liu K, Wang F, Liu Z, Zhang T, Li T, Zhang Y, Zhang F, Zhang J, Wang Y, Niu W, Jia S, Xie H, Tan G, Li C.
PMID: 25874912
PLoS One. 2015 Apr 13;10(4):e0125645. doi: 10.1371/journal.pone.0125645. eCollection 2015.

No abstract available.

Effects of 530 nm monochromatic light on basic fibroblast growth factor and transforming growth factor-β1 expression in Müller cells.

International journal of ophthalmology

Fu XY, Zhang XF, Xia W, Zhong L, Wang YM, Sun ZT, Xia J.
PMID: 26558199
Int J Ophthalmol. 2015 Oct 18;8(5):904-9. doi: 10.3980/j.issn.2222-3959.2015.05.09. eCollection 2015.

AIM: To expose rat retinal Müller cells to 530 nm monochromatic light and investigate the influence of varying light illumination times on basic fibroblast growth factor (bFGF) and transforming growth factor-β1 (TGF-β1) expression.METHODS: Three groups of rat retinal Müller...

Free-radical cascade alkylarylation of alkenes with simple alkanes: highly efficient access to oxindoles via selective (sp3)C-H and (sp2)C-H bond functionalization.

Organic letters

Li Z, Zhang Y, Zhang L, Liu ZQ.
PMID: 24354601
Org Lett. 2014 Jan 17;16(2):382-5. doi: 10.1021/ol4032478. Epub 2013 Dec 19.

A copper-catalyzed alkylarylation of alkenes with simple alkanes was achieved, which not only provided an efficient method to prepare various alkyl-substituted oxindoles, but also represented a novel strategy for selective sp(3) C-H functionalization/C-C bond formation via a free-radical cascade...

Synthesis of dibenzo[c,e]oxepin-5(7H)-ones from benzyl thioethers and carboxylic acids: rhodium-catalyzed double C-H activation controlled by different directing groups.

Angewandte Chemie (International ed. in English)

Zhang XS, Zhang YF, Li ZW, Luo FX, Shi ZJ.
PMID: 25757707
Angew Chem Int Ed Engl. 2015 Apr 27;54(18):5478-82. doi: 10.1002/anie.201500486. Epub 2015 Mar 10.

A rhodium(III)-catalyzed cross-coupling of benzyl thioethers and aryl carboxylic acids through the two directing groups is reported. Useful structures with diverse substituents were efficiently synthesized in one step with the cleavage of four bonds (CH, CS, OH) and the...

Heterozygous mutation of c.3521C>T in COL1A1 may cause mild osteogenesis imperfecta/Ehlers-Danlos syndrome in a Chinese family.

Intractable & rare diseases research

Shi X, Lu Y, Wang Y, Zhang YA, Teng Y, Han W, Han Z, Li T, Chen M, Liu J, Fang F, Dou C, Ren X, Han J.
PMID: 25674388
Intractable Rare Dis Res. 2015 Feb;4(1):49-53. doi: 10.5582/irdr.2014.01039.

Osteogenesis imperfecta (OI) is an inheritable connective tissue disorder with a broad clinical heterozygosis, which can be complicated by other connective tissue disorders like Ehlers-Danlos syndrome (EDS). OI/EDS are rarely documented. Most OI/EDS mutations are located in the N-anchor...

The loss-of-function of DNA methyltransferase 1 by siRNA impairs the growth of non-small cell lung cancer with alleviated side effects via reactivation of RASSF1A and APC .

Oncotarget

Lai Q, Xu YH, Chen Q, Tang L, Li AG, Zhang LF, Zhang CF, Song JF, Du ZZ.
PMID: 28938637
Oncotarget. 2017 Jul 26;8(35):59301-59311. doi: 10.18632/oncotarget.19573. eCollection 2017 Aug 29.

Hypermethylation of tumor suppressor genes (TSGs) promoters by DNA methyltransferase (DNMT) can be observed in almost all cancers which represent a hallmark of carcinogenesis, including lung cancer. DNMT inhibitors (e.g.5-Aza-CR/CdR) reactivate TSGs to exert anti-cancer activity and have been...

Association of genotypes of rs671 within.

Cancer biology & medicine

Zhang LQ, Song X, Zhao XK, Huang J, Zhang P, Wang LW, Meng H, Ku JW, Kong GQ, Jiang T, Li XM, Lv XL, Ma T, Yuan G, Wu MJ, Hu SJ, Lv S, Zhang TJ, Ji LF, Fan ZM, Wang NC, Zhang YW, Zhou FY, Wang LD.
PMID: 28443204
Cancer Biol Med. 2017 Feb;14(1):60-65. doi: 10.20892/j.issn.2095-3941.2016.0089.

OBJECTIVE: : This study aimed to determine if gastric cardia adenocarcinoma (GCA) risk was associated with the lys (A or *2) allele at the rs671 (glu504lys) polymorphism within the aldehyde dehydrogenase 2 (METHODS: : We designed a case-control study...

Showing 1 to 12 of 14165 entries