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Showing 1 to 12 of 332 entries
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Rhabdomyolysis in a patient taking nebivolol.

Kidney research and clinical practice

Kim YJ, Kim HR, Jeon HJ, Ju HJ, Chung S, Choi DE, Lee KW, Na KR.
PMID: 27668163
Kidney Res Clin Pract. 2016 Sep;35(3):182-6. doi: 10.1016/j.krcp.2015.09.003. Epub 2016 Jan 22.

β Blockers such as propranolol and labetalol are known to induce toxic myopathy because of their partial β2 adrenoceptor agonistic effect. Nebivolol has the highest β1 receptor affinity among β blockers, and it has never been reported to induce...

Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of measures.

Heart international

Vinik AI, Bloom HL, Colombo J.
PMID: 27004091
Heart Int. 2014 Aug 22;9(1):7-14. eCollection 2014.

BACKGROUND: Cardiovascular autonomic neuropathy (CAN) is recognized as a significant health risk. Specific and sensitive measures of CAN are needed for early identification and treatment to avoid complications, preferably in the preclinical state.OBJECTIVES: In this first of two articles,...

A Case of Isolated Celiac Artery Dissection Accompanied by Splenic Infarction Detected by Ultrasonography in the Emergency Department.

Case reports in cardiology

Emori K, Takeuchi N, Soneda J.
PMID: 27148460
Case Rep Cardiol. 2016;2016:8608496. doi: 10.1155/2016/8608496. Epub 2016 Apr 11.

A 46-year-old male with a history of hypertension visited the emergency department (ED) by ambulance complaining of sudden pain in the left side of his back. Ultrasonography (USG) performed at ED revealed splenic infarction along with occlusion and dissection...

Beta-Adrenergic Blockade Therapy for Autonomic Dysfunction is Less Effective for Elderly Patients with Heart Failure and Reduced Left Ventricular Ejection Fraction.

Japanese clinical medicine

Shimamoto K, Kawana M.
PMID: 26483614
Jpn Clin Med. 2015 Oct 11;6:21-7. doi: 10.4137/JCM.S30488. eCollection 2015.

OBJECTIVE: Heart rate variability (HRV) has been reported to be an independent predictor of all-cause and sudden cardiac death in patients with heart failure. In the aging heart, however, both autonomic and cardiac functions appear to be altered. We...

Potential additive effects of ticagrelor, ivabradine, and carvedilol on sinus node.

Case reports in cardiology

Di Serafino L, Rotolo FL, Boggi A, Colantonio R, Serdoz R, Monti F.
PMID: 25328715
Case Rep Cardiol. 2014;2014:932595. doi: 10.1155/2014/932595. Epub 2014 Sep 29.

A 51-year-old male patient presented to the emergency room with an anterior ST-elevation myocardial infarction. After a loading dose of both ticagrelor and aspirin, the patient underwent primary-PCI on the left anterior descending coronary artery with stent implantation. After...

Is it time to replace propranolol with carvedilol for portal hypertension?.

World journal of gastrointestinal endoscopy

Abid S, Ali S, Baig MA, Waheed AA.
PMID: 25992192
World J Gastrointest Endosc. 2015 May 16;7(5):532-9. doi: 10.4253/wjge.v7.i5.532.

Beta-adrenergic receptor antagonists (β-blockers) have been well established for use in portal hypertension for more than three decades. Different Non-selective β-blockers like propranolol, nadolol, timolol, atenolol, metoprolol and carvedilol have been in clinical practice in patients with cirrhosis. Carvedilol...

Arbutin and decrease of potentially toxic substances generated in human blood neutrophils.

Interdisciplinary toxicology

Pečivová J, Nosál' R, Sviteková K, Mačičková T.
PMID: 26109900
Interdiscip Toxicol. 2014 Dec;7(4):195-200. doi: 10.2478/intox-2014-0028. Epub 2015 Mar 04.

Neutrophils, highly motile phagocytic cells, constitute the first line of host defense and simultaneously they are considered to be central cells of chronic inflammation. In combination with standard therapeutic procedures, natural substances are gaining interest as an option for...

Clinical effects of carvedilol and trimetazidine for the treatmentof alcoholic myocardiopathy.

Experimental and therapeutic medicine

Li H, Liu FY, Li XL, Li XM, Zhu L.
PMID: 27446307
Exp Ther Med. 2016 Aug;12(2):979-982. doi: 10.3892/etm.2016.3363. Epub 2016 May 19.

The aim of the study was to compare the clinical effects of carvedilol and trimetazidine for the treatment of alcoholic cardiomyopathy. A total of 60 patients diagnosed with alcoholic cardiomyopathy were enrolled in the study. The patients were randomly...

Quantifying the Structural Dynamics of Pharmaceuticals in the Glassy State.

The journal of physical chemistry letters

Wojnarowska Z, Roland CM, Kolodziejczyk K, Swiety-Pospiech A, Grzybowska K, Paluch M.
PMID: 26286764
J Phys Chem Lett. 2012 May 17;3(10):1238-41. doi: 10.1021/jz300349a. Epub 2012 Apr 27.

Structural dynamics in the glassy state of two protic ionic liquids, carvedilol phosphate and procaine hydrochloride, were characterized from analysis of changes in the conductivity relaxation times during physical aging. The obtained relaxation times, having a magnitude exceeding feasible...

Beta-Blockers and Oxidative Stress in Patients with Heart Failure.

Pharmaceuticals (Basel, Switzerland)

Nakamura K, Murakami M, Miura D, Yunoki K, Enko K, Tanaka M, Saito Y, Nishii N, Miyoshi T, Yoshida M, Oe H, Toh N, Nagase S, Kohno K, Morita H, Matsubara H, Kusano KF, Ohe T, Ito H.
PMID: 26791643
Pharmaceuticals (Basel). 2011 Aug 05;4(8):1088-100. doi: 10.3390/ph4081088.

Oxidative stress has been implicated in the pathogenesis of heart failure. Reactive oxygen species (ROS) are produced in the failing myocardium, and ROS cause hypertrophy, apoptosis/cell death and intracellular Ca(2+) overload in cardiac myocytes. ROS also cause damage to...

β-Blockers in hypertension, diabetes, heart failure and acute myocardial infarction: a review of the literature.

Open heart

DiNicolantonio JJ, Fares H, Niazi AK, Chatterjee S, D'Ascenzo F, Cerrato E, Biondi-Zoccai G, Lavie CJ, Bell DS, O'Keefe JH.
PMID: 25821584
Open Heart. 2015 Mar 21;2(1):e000230. doi: 10.1136/openhrt-2014-000230. eCollection 2015.

β-Blockers (BBs) are an essential class of cardiovascular medications for reducing morbidity and mortality in patients with heart failure (HF). However, a large body of data indicates that BBs should not be used as first-line therapy for hypertension (HTN)....

Cyclodextrine screening for the chiral separation of carvedilol by capillary electrophoresis.

Iranian journal of pharmaceutical research : IJPR

Hancu G, Cârje A, Iuga I, Fülöp I, Szabó ZI.
PMID: 25901149
Iran J Pharm Res. 2015;14(2):425-33.

Carvedilol is administered as a racemic mixture of the R(+)- and S(-)-enantiomers, although it was demonstrated that the two enantiomers exhibit different pharmacological effects and stereoselective pharmacokinetics. The aim of this study was the evaluation of several native and...

Showing 1 to 12 of 332 entries