Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 134 entries
Sorted by: Best Match Show Resources per page
Imp3 expression in benign and malignant thyroid tumors and hyperplastic nodules.

Balkan medical journal

Kulaçoğlu S, Erkılınç G.
PMID: 25759769
Balkan Med J. 2015 Jan;32(1):30-7. doi: 10.5152/balkanmedj.2015.15547. Epub 2015 Jan 01.

BACKGROUND: IMP3, a member of insulin-like growth factor II m RNA binding protein family, seems to be promising in the diagnosis of carcinomas of many organs as well as malignant melanomas and some sarcomas. It is postulated that it...

Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma.

Case reports in endocrinology

Kim SW, Lee SE, Oh YL, Kim S, Park SH, Kim JH.
PMID: 27957352
Case Rep Endocrinol. 2016;2016:5731417. doi: 10.1155/2016/5731417. Epub 2016 Nov 10.

Nonislet cell tumor hypoglycemia (NICTH) is a rare but serious paraneoplastic syndrome in which a tumor secretes incompletely processed precursors of insulin-like growth factor-II (IGF-II), causing hypoglycemia. Here, we report an exceptional case of NICTH caused by nonfunctioning adrenocortical...

Dung-Shen Downregulates the Synergistic Apoptotic Effects of Angiotensin II Plus Leu 27-IGF II on Cardiomyoblasts.

Acta Cardiologica Sinica

Chang KS, Lee NH, Kuo WW, Hu WS, Chang MH, Tsai FJ, Tsai KH, Yang YS, Chen TS, Huang CY.
PMID: 27122769
Acta Cardiol Sin. 2014 Jan;30(1):56-66.

BACKGROUND: Insulin growth factor II (IGFII) is expressed after ischemic stress in pig hearts and after myocardial infarction in humans. However, its receptor (IGFIIR) cannot be found in normal adult hearts. Moreover, a mouse IGFII overexpression model showed a...

Prognostic value of high IMP3 expression in solid tumors: a meta-analysis.

OncoTargets and therapy

Chen L, Xie Y, Li X, Gu L, Gao Y, Tang L, Chen J, Zhang X.
PMID: 28652767
Onco Targets Ther. 2017 Jun 06;10:2849-2863. doi: 10.2147/OTT.S128810. eCollection 2017.

BACKGROUND: Accumulated studies have investigated the prognostic role of insulin-like growth factor II mRNA-binding protein 3 (IMP3) in various cancers, but inconsistent and controversial results were obtained. Therefore, we performed a systematic review and meta-analysis to investigate the potential...

Anthocyanin Attenuates Doxorubicin-Induced Cardiomyotoxicity via Estrogen Receptor-α/β and Stabilizes HSF1 to Inhibit the IGF-IIR Apoptotic Pathway.

International journal of molecular sciences

Huang PC, Kuo WW, Shen CY, Chen YF, Lin YM, Ho TJ, Padma VV, Lo JF, Huang CY, Huang CY.
PMID: 27657062
Int J Mol Sci. 2016 Sep 21;17(9). doi: 10.3390/ijms17091588.

Doxorubicin (Dox) is extensively used for chemotherapy in different types of cancer, but its use is limited to because of its cardiotoxicity. Our previous studies found that doxorubicin-induced insulin-like growth factor II receptor (IGF-IIR) accumulation causes cardiomyocytes apoptosis via...

Insulin-Like Growth Factor II mRNA-Binding Protein 3 (IMP3) as a Useful Immunohistochemical Marker for the Diagnosis of Adenocarcinoma of Small Intestine.

Acta histochemica et cytochemica

Daikuhara S, Uehara T, Higuchi K, Hosaka N, Iwaya M, Maruyama Y, Matsuda K, Arakura N, Tanaka E, Ota H.
PMID: 26855452
Acta Histochem Cytochem. 2015 Dec 25;48(6):193-204. doi: 10.1267/ahc.15021. Epub 2015 Dec 18.

The biological characteristics and roles of insulin-like growth factor II mRNA-binding protein 3 protein (IMP3) expression in small-intestinal adenocarcinoma were investigated. The value of IMP3 immunostaining in the diagnosis of small-intestinal epithelial lesions was also evaluated. Immunohistochemical expression of...

Late recurrence of a malignant hypoglycemia-inducing pelvic solitary fibrous tumor secreting high-molecular-weight insulin-like growth factor-II: A case report with protein analysis.

Oncology letters

Ishihara H, Omae K, Iizuka J, Kobayashi H, Fukuda I, Kondo T, Hizuka N, Nagashima Y, Tanabe K.
PMID: 27347168
Oncol Lett. 2016 Jul;12(1):479-484. doi: 10.3892/ol.2016.4665. Epub 2016 Jun 01.

The present study reports a case of recurrent malignant pelvic solitary fibrous tumor (SFT) that induced non-islet cell tumor hypoglycemia via high-molecular-weight insulin-like growth factor-II in a 72-year-old male patient. The tumor recurred ~12 years after the complete resection...

The oncofetal protein IMP3 is an indicator of early recurrence and poor outcome in mucoepidermoid carcinoma of salivary glands.

Cancer biology & medicine

Elshafey MR, Ahmed RA, Mourad MI, Gaballah ET.
PMID: 27458536
Cancer Biol Med. 2016 Jun;13(2):286-95. doi: 10.20892/j.issn.2095-3941.2016.0037.

OBJECTIVE: Mucoepidermoid carcinoma (MEC) is the most common primary malignancy of the salivary glands. Insulin-like growth factor-II mRNA-binding protein-3 (IMP3) is an important prognostic factor in some cancers and a tool that differentiates between benign and malignant pancreatic lesions....

Severe hypoglycemia associated with insulin-like growth factor II-producing liver metastasis from gastric carcinoma treated with overnight total parenteral nutrition via a central vein catheter reserve port.

Clinical journal of gastroenterology

Koizumi Y, Hiraoka A, Michitaka K, Tazuya N, Ichiryu M, Nakahara H, Ochi H, Tanabe A, Hidaka S, Kodama A, Uehara T, Hasebe A, Miyamoto Y, Ninomiya T, Kumagi T, Abe M, Matsuura B, Horiike N, Hiasa Y, Onji M.
PMID: 26190708
Clin J Gastroenterol. 2011 Apr;4(2):68-72. doi: 10.1007/s12328-010-0200-y. Epub 2011 Jan 21.

Hypoglycemia caused by insulin-like growth factor II is difficult to control. A 77-year-old woman was diagnosed with gastric cancer and multiple liver metastases in September 2006 and underwent chemotherapy; however, at that time there were no symptoms of hypoglycemia....

[Endometrial insulin-like growth factor II and type I receptor in unexplained infertility and its steroid regulation].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences

Wu RJ, Zhou FZ.
PMID: 12596304
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2002 Jun;31(3):163-166. doi: 10.3785/j.issn.1008-9292.2002.03.007.

OBJECTIVE: To investigate the endometrial expression of insulin-like growth factor II(IGF-II) and type I receptor(IGF-1R) in unexplained infertility. METHODS: Reverse transcription-polymerase chain reaction (RT-PCR) was used to detect and quantify endometrial IGF-II and IGF-I R mRNA experession in the...

Insulin-like growth factor II prevents apoptosis in a human teratoma derived cell line.

Clinical molecular pathology

Granerus M, Bierke P, Zumkeller W, Smith J, Engström W, Schofield PN.
PMID: 16695997
Clin Mol Pathol. 1995 Jun;48(3):M153-7. doi: 10.1136/mp.48.3.m153.

Aim-To study how insulin-like growth factor II (IGF-II) affects the behaviour of human teratoma cells.Methods-The human pluripotential teratoma cell line Tera 2 was cultured under serum-free conditions in the presence or absence of IGF-II. Effects on cell proliferation and...

Differential regulation of collagen gene expression in granulation tissue and non-repair connective tissues in vitamin C-deficient guinea pigs.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

Kipp D, Wilson S, Gosiewska A, Peterkofsky B.
PMID: 17173648
Wound Repair Regen. 1995 Apr-Jun;3(2):192-203. doi: 10.1046/j.1524-475X.1995.30211.x.

Poor wound healing during vitamin C deficiency is thought to be due to decreased hydroxylation of proline residues in collagen. In non-repair connective tissues of guinea pigs, however, procollagen gene expression is not decreased until weight loss occurs during...

Showing 1 to 12 of 134 entries