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Showing 1 to 12 of 1485 entries
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Divergence of macrophage phagocytic and antimicrobial programs in leprosy

Louis Stokes Alliances for Minority Participation AND Program Evaluation

Montoya D, Ochoa MT, Teles RMB.
GSID: e-DLXLz4pcIJ
D Montoya, D Cruz, RMB Teles, DJ Lee, MT Ochoa… - Cell host & …, 2009 - Elsevier

Effective innate immunity against many microbial pathogens requires macrophage programs that upregulate phagocytosis and direct antimicrobial pathways, two functions generally assumed to be coordinately regulated. We investigated the regulation of these key functions in human blood-derived macrophages. Interleukin-10 (IL-10)...

The effects of cyclooxygenase inhibitors on the brain inflammatory response following traumatic brain injury in rats.

Iranian journal of basic medical sciences

Keshavarzi Z, Khaksari M, Razmi Z, Soltani Hekmat A, Naderi V, Rostami S.
PMID: 23492757
Iran J Basic Med Sci. 2012 Sep;15(5):1102-5.

OBJECTIVES: Cytokines such as IL-1β are involved in inflammatory responses. This study evaluated the role of two different kinds of drugs (ibuprofen and celecoxib) on brain IL-10 and IL-1β after traumatic brain injury (TBI) in male rats.MATERIALS AND METHODS:...

Systemic reduction of interleukin-4 or interleukin-10 fails to reduce the frequency or severity of experimental cytomegalovirus retinitis in mice with retrovirus-induced immunosuppression.

Ophthalmology and eye diseases

Blalock EL, Chien H, Dix RD.
PMID: 23650460
Ophthalmol Eye Dis. 2012 Sep 25;4:79-90. doi: 10.4137/OED.S10294. Print 2012.

Interleukin-4 (IL-4) and interleukin-10 (IL-10) are key cytokines whose increased production during systemic HIV infection has been associated with decreased cellular immunity during AIDS. We examined whether HIV-induced stimulation of IL-4 or IL-10 production leads to increased susceptibility to...

Cutaneous leukocytoclastic vasculitis: the role of lymphocytes and related immune markers.

Postepy dermatologii i alergologii

Gambichler T, Kulik MA, Skrygan M, Rooms I, Höxtermann S.
PMID: 28951703
Postepy Dermatol Alergol. 2017 Aug;34(4):299-305. doi: 10.5114/ada.2017.69307. Epub 2017 Aug 01.

INTRODUCTION: Apart from neutrophils, other immune cells may play a significant pathogenetic role in cutaneous leukocytoclastic vasculitis (CLV).AIM: To investigate lymphocytes and related immunological factors in patients with CLV requiring systemic glucocorticosteroid treatment.MATERIAL AND METHODS: Fourteen patients with severe...

Low levels of interleukin-10 in patients with transfusion-related acute lung injury.

Annals of translational medicine

Kapur R, Kim M, Rebetz J, Rondina MT, Porcelijn L, Semple JW.
PMID: 28861436
Ann Transl Med. 2017 Aug;5(16):339. doi: 10.21037/atm.2017.04.37.

No abstract available.

Deficient regulatory B cells in human chronic graft-versus-host disease.

Oncoimmunology

de Masson A, Socié G, Bagot M, Bensussan A, Bouaziz JD.
PMID: 26140245
Oncoimmunology. 2015 Apr 01;4(7):e1016707. doi: 10.1080/2162402X.2015.1016707. eCollection 2015 Jul.

Human chronic graft-versus-host disease (cGVHD) is a frequent and disabling complication of allogeneic hematopoietic stem cell transplantation. Regulatory B cells (Bregs) are IL-10-producing B cells that are able to inhibit the innate and adaptive immune responses. We have recently...

Role of high-mobility group box 1 in patients with acute obstructive suppurative cholangitis-induced sepsis.

Journal of inflammation research

Singh A, Feng Y, Mahato N, Li J, Wu C, Gong J.
PMID: 25792849
J Inflamm Res. 2015 Mar 11;8:71-7. doi: 10.2147/JIR.S77539. eCollection 2015.

BACKGROUND: High-mobility group box 1 (HMGB1) is a proinflammatory cytokine that plays an active role during the pathogenesis of inflammatory processes. The primary aim of this study was to detect whether HMGB1 is involved in the pathogenesis of acute...

Association between three interleukin-10 gene polymorphisms and coronary artery disease risk: a meta-analysis.

International journal of clinical and experimental medicine

Wang BJ, Liu J, Geng J, Zhang Q, Hu TT, Xu B.
PMID: 26770379
Int J Clin Exp Med. 2015 Oct 15;8(10):17842-55. eCollection 2015.

BACKGROUND: Previous studies have investigated the associations between interleukin-10 (IL-10) gene polymorphisms (-592C/A, -819C/T and -1082G/A) and risk of coronary artery disease (CAD). However, the results were inconsistent. The aim of this study was to clarify the relationship between...

Ultraviolet-induced alloantigen-specific immunosuppression in transplant immunity.

World journal of transplantation

Hori T, Kuribayashi K, Saito K, Wang L, Torii M, Uemoto S, Iida T, Yagi S, Kato T.
PMID: 25815267
World J Transplant. 2015 Mar 24;5(1):11-8. doi: 10.5500/wjt.v5.i1.11.

After the first observation of the immunosuppressive effects of ultraviolet (UV) irradiation was reported in 1974, therapeutic modification of immune responses by UV irradiation began to be investigated in the context immunization. UV-induced immunosuppression is via the action of...

Corrigendum to "Laquinimod ameliorates spontaneous colitis in interleukin-10-gene-deficient mice with improved barrier function" [Int. Immunopharmacol. (2015) 423-432].

International immunopharmacology

Sun J, Shen X, Dong J, Zhao J, Zuo L, Wang H, Li Y, Zhu W, Gong J, Li J.
PMID: 27130814
Int Immunopharmacol. 2016 Jun;35:341. doi: 10.1016/j.intimp.2016.03.012. Epub 2016 Apr 05.

No abstract available.

Little association between the interleukin 10-3575T/A polymorphism and cancer risk: pooled analysis of 15608 cancer cases and 17539 controls.

International journal of clinical and experimental medicine

Zhu B, Xiao C, Zhu B, Zheng Z, Liang J.
PMID: 26550419
Int J Clin Exp Med. 2015 Aug 15;8(8):14335-44. eCollection 2015.

The aim of the present work was to evaluate the association between the interleukin 10 (IL-10) -3575T/A (rs1800890) polymorphism and cancer risk. We performed a met-analysis based on 15 studies, including 15608 cancer cases and 17539 controls. We used...

Efficacy of Different Durations of Intravenous Methylprednisolone Treatment in Relapses of Multiple Sclerosis.

Noro psikiyatri arsivi

Kulu U, Tiftikcioğlu Bİ, Zorlu Y, Çetiner M, Şener U, Tuna G, Kirkali G.
PMID: 28566960
Noro Psikiyatr Ars. 2017 Mar;54(1):57-61. doi: 10.5152/npa.2016.12382. Epub 2016 Mar 28.

INTRODUCTION: Relapses of multiple sclerosis (MS) are usually treated with high-dose intravenous methylprednisolone (IVMP), given over 3-10 days. There is no consensus on the optimal duration of treatment. In this study, we aimed to investigate whether longer treatment provides...

Showing 1 to 12 of 1485 entries