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Modulatory effect of semelil (ANGIPARS™) on isoproterenol induced cardiac injury.

EXCLI journal

Joukar S, Najafipour H, Mirzaeipour F, Nasri H, Ahmadi MY, Badinloo M.
PMID: 26417221
EXCLI J. 2013 Feb 19;12:122-9. eCollection 2013.

Administration of semelil (ANGIPARS™) has been successful in the treatment of diabetic foot ulcer. Considering the improvement of blood flow and anti-inflammatory effect that are attributed to this drug, we investigated its effect on cardiovascular performance in rabbits with...

Activation of β-adrenergic receptor promotes cellular proliferation in human glioblastoma.

Oncology letters

He JJ, Zhang WH, Liu SL, Chen YF, Liao CX, Shen QQ, Hu P.
PMID: 28927156
Oncol Lett. 2017 Sep;14(3):3846-3852. doi: 10.3892/ol.2017.6653. Epub 2017 Jul 21.

Glioblastoma multiforme is the most common and aggressive form of primary malignant brain tumor. Previous evidence demonstrates that β-adrenergic receptors (β-ARs) are closely associated with the occurrence and development of brain tumors. However, the functional role of β-ARs in...

Combinational effect of resveratrol and atorvastatin on isoproterenol-induced cardiac hypertrophy in rats.

Journal of pharmacy & bioallied sciences

Chakraborty S, Pujani M, Haque SE.
PMID: 26229360
J Pharm Bioallied Sci. 2015 Jul-Sep;7(3):233-8. doi: 10.4103/0975-7406.160037.

INTRODUCTION: Resveratrol is a natural polyphenol present mainly in grapes. It has been shown to offer strong cardio protection in animal models due to its ability to correct lipid peroxidation and maintain antioxidants level. Atorvastatin, a HMG-CoA reductase inhibitor,...

Greater Beta-Adrenergic Receptor Mediated Vasodilation in Women Using Oral Contraceptives.

Frontiers in physiology

Limberg JK, Peltonen GL, Johansson RE, Harrell JW, Kellawan JM, Eldridge MW, Sebranek JJ, Walker BJ, Schrage WG.
PMID: 27375493
Front Physiol. 2016 Jun 08;7:215. doi: 10.3389/fphys.2016.00215. eCollection 2016.

BACKGROUND: β-adrenergic receptors play an important role in mitigating the pressor effects of sympathetic nervous system activity in young women. Based on recent data showing oral contraceptive use in women abolishes the relationship between muscle sympathetic nervous system activity...

Jujuboside A Protects H9C2 Cells from Isoproterenol-Induced Injury via Activating PI3K/Akt/mTOR Signaling Pathway.

Evidence-based complementary and alternative medicine : eCAM

Han D, Wan C, Liu F, Xu X, Jiang L, Xu J.
PMID: 27293469
Evid Based Complement Alternat Med. 2016;2016:9593716. doi: 10.1155/2016/9593716. Epub 2016 May 16.

Jujuboside A is a kind of the saponins isolated from the seeds of Ziziphus jujuba, which possesses multiple biological effects, such as antianxiety, antioxidant, and anti-inflammatory effects; however, its mediatory effect on isoproterenol-stimulated cardiomyocytes has not been investigated yet....

Myocardial Salvaging Effects of Berberine in Experimental Diabetes Co-Existing with Myocardial Infarction.

Journal of clinical and diagnostic research : JCDR

Suman RK, Borde MK, Mohanty IR, Maheshwari U, Deshmukh YA.
PMID: 27134894
J Clin Diagn Res. 2016 Mar;10(3):FF13-8. doi: 10.7860/JCDR/2016/15794.7459. Epub 2016 Mar 01.

INTRODUCTION: Berberine, an isoquinoline alkaloid isolated from the Berberis aristata, has been shown to display a wide array of pharmacological activities (hypoglycaemic and hypolipidemic).AIM: The present study was designed to investigate whether these pharmacological properties translate into the cardioprotective...

Superior Vena Cava Isolation In Ablation Of Atrial Fibrillation.

Journal of atrial fibrillation

Higuchi K, Yamauchi Y, Hirao K.
PMID: 27957077
J Atr Fibrillation. 2014 Jun 30;7(1):1032. doi: 10.4022/jafib.1032. eCollection 2014.

Superior vena cava (SVC) is one of the most important non-pulmonary vein (PV) origins of atrial fibrillation (AF). SVC isolation (SVCI) is effective especially in patients with paroxysmal AF from SVC origin. However, SVCI should be carefully performed because...

Cardiac adaptation to high altitude in the plateau pika (Ochotona curzoniae).

Physiological reports

Pichon A, Zhenzhong B, Marchant D, Jin G, Voituron N, Haixia Y, Favret F, Richalet JP, Ge RL.
PMID: 24303117
Physiol Rep. 2013 Jul;1(2):e00032. doi: 10.1002/phy2.32. Epub 2013 Jul 18.

The aim of this study was to assess maximal heart rate (HR) and heart morphological changes in high altitude living "plateau pikas" and rats bred at 2260 m. Rats and pikas were catheterized to measure HR (2260 m). After...

Short-term HFD does not alter lipolytic function of adipocytes.


Wiedemann MS, Wueest S, Grob A, Item F, Schoenle EJ, Konrad D.
PMID: 24719784
Adipocyte. 2014 Apr 01;3(2):115-20. doi: 10.4161/adip.27575. Epub 2014 Jan 08.

A short bout of high fat diet (HFD) impairs glucose tolerance and hepatic insulin sensitivity. We recently identified adipose tissue inflammation and resulting dysfunctional adipose tissue-liver cross-talk as an early event in the development of HFD-induced hepatic insulin resistance....

Ventricular arrhythmia in patients with prolonged QT interval during liver transplantation: two cases report.

Korean journal of anesthesiology

Kim MS, Kim NY, Park JE, Nam SH.
PMID: 25558343
Korean J Anesthesiol. 2014 Dec;67(6):416-20. doi: 10.4097/kjae.2014.67.6.416. Epub 2014 Dec 29.

QT interval prolongation is associated with an increased risk of ventricular arrhythmia in various conditions. Cardiac electrophysiologic abnormalities including QT interval prolongation are well documented in patients with advanced liver cirrhosis. We report two cases of patients with QT...

Recurrent syncope in two patients with a sigmoid-shaped interventricular septum and no left ventricular hypertrophy.

Journal of arrhythmia

Yamaguchi Y, Mizumaki K, Iwamoto J, Nishida K, Sakamoto T, Nakatani Y, Kataoka N, Inoue H.
PMID: 26702321
J Arrhythm. 2015 Dec;31(6):391-4. doi: 10.1016/j.joa.2015.04.006. Epub 2015 May 28.

Sigmoid-shaped interventricular septum (SIS) is not uncommon in elderly patients and is considered a normal part of the aging process. However, several patients have been reported to have clinical symptoms due to the narrowing of the left ventricular outflow...

Cardiomyocyte-specific TβR2 knockout mice are more susceptible to cardiac hypertrophy induced by adrenergic agonist stimulation.

Current molecular medicine

Fan X, Liu L, Li Z, Peng X, Jiang Z, Guan Y, Wu X, Yang X, Wang J.
PMID: 26349497
Curr Mol Med. 2016 Apr 29; Epub 2016 Apr 29.

TGF-β signaling is shown to be involved in cardiac remodeling, but the detailed function and underlying mechanism are still incompletely understood. In this study, we generated cardiomyocyte-specific TGF-β type 2 receptor (TβR2) knockout mice to study the function of...

Showing 1 to 12 of 726 entries