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Showing 1 to 12 of 27 entries
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Secondary Data Analytics of Aquaporin Expression Levels in Glioblastoma Stem-Like Cells.

Cancer informatics

Isokpehi RD, Wollenberg Valero KC, Graham BE, Pacurari M, Sims JN, Udensi UK, Ndebele K.
PMID: 26279619
Cancer Inform. 2015 Jul 30;14:95-103. doi: 10.4137/CIN.S22058. eCollection 2015.

Glioblastoma is the most common brain tumor in adults in which recurrence has been attributed to the presence of cancer stem cells in a hypoxic microenvironment. On the basis of tumor formation in vivo and growth type in vitro,...

Evaluative profiling of arsenic sensing and regulatory systems in the human microbiome project genomes.

Microbiology insights

Isokpehi RD, Udensi UK, Simmons SS, Hollman AL, Cain AE, Olofinsae SA, Hassan OA, Kashim ZA, Enejoh OA, Fasesan DE, Nashiru O.
PMID: 25452698
Microbiol Insights. 2014 Nov 11;7:25-34. doi: 10.4137/MBI.S18076. eCollection 2014.

The influence of environmental chemicals including arsenic, a type 1 carcinogen, on the composition and function of the human-associated microbiota is of significance in human health and disease. We have developed a suite of bioinformatics and visual analytics methods...

Associations of adiponectin with individual European ancestry in African Americans: the Jackson Heart Study.

Frontiers in genetics

Bidulescu A, Choudhry S, Musani SK, Buxbaum SG, Liu J, Rotimi CN, Wilson JG, Taylor HA, Gibbons GH.
PMID: 24575123
Front Genet. 2014 Feb 10;5:22. doi: 10.3389/fgene.2014.00022. eCollection 2014.

BACKGROUND: Compared with European Americans, African Americans (AAs) exhibit lower levels of the cardio-metabolically protective adiponectin even after accounting for adiposity measures. Because few studies have examined in AA the association between adiponectin and genetic admixture, a dense panel...

What does genomic medicine mean for diverse populations?.

Molecular genetics & genomic medicine

Adeyemo A, Rotimi C.
PMID: 24498625
Mol Genet Genomic Med. 2014 Jan;2(1):3-6. doi: 10.1002/mgg3.63. Epub 2014 Jan 10.

No abstract available.

Circulating adiponectin is associated with renal function independent of age and serum lipids in west africans.

International journal of nephrology

Doumatey AP, Zhou J, Huang H, Adeleye J, Balogun W, Fasanmade O, Johnson T, Oli J, Okafor G, Amoah A, Eghan B, Agyenim-Boateng K, Acheampong J, Adebamowo C, Adeyemo A, Rotimi CN.
PMID: 22957255
Int J Nephrol. 2012;2012:730920. doi: 10.1155/2012/730920. Epub 2012 Aug 22.

Adiponectin, a protein secreted by adipose tissue, has been associated with renal dysfunction. However, these observations have not been adequately investigated in large epidemiological studies of healthy individuals in general and in African populations in particular. Hence, we designed...

Electronic Cigarette Use among Mississippi Adults, 2015.

Journal of addiction

Mendy VL, Vargas R, Cannon-Smith G, Payton M, Byambaa E, Zhang L.
PMID: 28900552
J Addict. 2017;2017:5931736. doi: 10.1155/2017/5931736. Epub 2017 Aug 16.

Electronic cigarettes (e-cigarettes) are battery-powered devices that deliver nicotine in the form of aerosol. We identify differences and associations in e-cigarette use by sociodemographic characteristics and describe the reported reasons for initiating use among Mississippi adults. We used the...

Variation in APOL1 Contributes to Ancestry-Level Differences in HDLc-Kidney Function Association.

International journal of nephrology

Bentley AR, Doumatey AP, Chen G, Huang H, Zhou J, Shriner D, Jiang C, Zhang Z, Liu G, Fasanmade O, Johnson T, Oli J, Okafor G, Eghan BA, Agyenim-Boateng K, Adeleye J, Balogun W, Adebamowo C, Amoah A, Acheampong J, Adeyemo A, Rotimi CN.
PMID: 22973513
Int J Nephrol. 2012;2012:748984. doi: 10.1155/2012/748984. Epub 2012 Sep 02.

Low levels of high-density cholesterol (HDLc) accompany chronic kidney disease, but the association between HDLc and the estimated glomerular filtration rate (eGFR) in the general population is unclear. We investigated the HDLc-eGFR association in nondiabetic Han Chinese (HC, n...

Genome science and health disparities: a growing success story?.

Genome medicine

Rotimi C, Shriner D, Adeyemo A.
PMID: 23899246
Genome Med. 2013 Jul 29;5(7):61. doi: 10.1186/gm465. eCollection 2013.

No abstract available.

Using a "genomics tool" to develop disease prevention strategy in a low-income setting: lessons from the podoconiosis research project.

Journal of community genetics

Tekola Ayele F, Adeyemo A, Rotimi CN.
PMID: 22430163
J Community Genet. 2012 Oct;3(4):303-9. doi: 10.1007/s12687-012-0086-0. Epub 2012 Mar 20.

No abstract available.

Social Determinants of Kidney Health: Focus on Poverty.

Clinical journal of the American Society of Nephrology : CJASN

Norris KC, Beech BM.
PMID: 33441465
Clin J Am Soc Nephrol. 2021 May 08;16(5):809-811. doi: 10.2215/CJN.12710820. Epub 2021 Jan 13.

No abstract available.

Developmental Regulation of Genes Encoding Universal Stress Proteins in Schistosoma mansoni.

Gene regulation and systems biology

Isokpehi RD, Mahmud O, Mbah AN, Simmons SS, Avelar L, Rajnarayanan RV, Udensi UK, Ayensu WK, Cohly HH, Brown SD, Dates CR, Hentz SD, Hughes SJ, Smith-McInnis DR, Patterson CO, Sims JN, Turner KT, Williams BS, Johnson MO, Adubi T, Mbuh JV, Anumudu CI, Adeoye GO, Thomas BN, Nashiru O, Oliveira G.
PMID: 22084571
Gene Regul Syst Bio. 2011;5:61-74. doi: 10.4137/GRSB.S7491. Epub 2011 Sep 19.

The draft nuclear genome sequence of the snail-transmitted, dimorphic, parasitic, platyhelminth Schistosoma mansoni revealed eight genes encoding proteins that contain the Universal Stress Protein (USP) domain. Schistosoma mansoni is a causative agent of human schistosomiasis, a severe and debilitating...

Proteomics-Based Identification of Differentially Abundant Proteins from Human Keratinocytes Exposed to Arsenic Trioxide.

Journal of proteomics & bioinformatics

Udensi UK, Tackett AJ, Byrum S, Avaritt NL, Sengupta D, Moreland LW, Tchounwou PB, Isokpehi RD.
PMID: 25419056
J Proteomics Bioinform. 2014 Jul;7(7):166-178. doi: 10.4172/jpb.1000317.

INTRODUCTION: Arsenic is a widely distributed environmental toxicant that can cause multi-tissue pathologies. Proteomic assays allow for the identification of biological processes modulated by arsenic in diverse tissue types.METHOD: The altered abundance of proteins from HaCaT human keratinocyte cell...

Showing 1 to 12 of 27 entries