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Showing 1 to 12 of 12 entries
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Thyroid hormone analogues and derivatives: Actions in fatty liver.

World journal of hepatology

Coppola M, Glinni D, Moreno M, Cioffi F, Silvestri E, Goglia F.
PMID: 24672641
World J Hepatol. 2014 Mar 27;6(3):114-29. doi: 10.4254/wjh.v6.i3.114.

Fatty liver or nonalcoholic fatty liver disease (NAFLD), a problem of increasing clinical significance and prevalence worldwide, is associated with increased risk for the development of cirrhosis and hepatocellular carcinoma. Although several therapeutic approaches can be used in the...

Thyroid Hormones Play Role in Sarcopenia and Myopathies.

Frontiers in physiology

Bloise FF, Oliveira TS, Cordeiro A, Ortiga-Carvalho TM.
PMID: 29910736
Front Physiol. 2018 May 23;9:560. doi: 10.3389/fphys.2018.00560. eCollection 2018.

Skeletal muscle maintains posture and enables movement by converting chemical energy into mechanical energy, further contributing to basal energy metabolism. Thyroid hormones (thyroxine, or T4, and triiodothyronine, or T3) participate in contractile function, metabolic processes, myogenesis and regeneration of...

Structures of Endocrine-Disrupting Chemicals Correlate with the Activation of 12 Classic Nuclear Receptors.

Environmental science & technology

Tan H, Chen Q, Hong H, Benfenati E, Gini GC, Zhang X, Yu H, Shi W.
PMID: 34859678
Environ Sci Technol. 2021 Dec 21;55(24):16552-16562. doi: 10.1021/acs.est.1c04997. Epub 2021 Dec 03.

Endocrine-disrupting chemicals (EDCs) can inadvertently interact with 12 classic nuclear receptors (NRs) that disrupt the endocrine system and cause adverse effects. There is no widely accepted understanding about what structural features make thousands of EDCs able to activate different...

Hemostasis in Hypothyroidism and Autoimmune Thyroid Disorders.

International journal of endocrinology and metabolism

Ordookhani A, Burman KD.
PMID: 29026409
Int J Endocrinol Metab. 2017 Mar 09;15(2):e42649. doi: 10.5812/ijem.42649. eCollection 2017 Apr.

CONTEXT: There are contradictory results on the effect of hypothyroidism on the changes in hemostasis. Inadequate population-based studies limited their clinical implications, mainly on the risk of venous thromboembolism (VTE). This paper reviews the studies on laboratory and population-based...

An Intimate Relationship between Thyroid Hormone and Skin: Regulation of Gene Expression.

Frontiers in endocrinology

Antonini D, Sibilio A, Dentice M, Missero C.
PMID: 23986743
Front Endocrinol (Lausanne). 2013 Aug 22;4:104. doi: 10.3389/fendo.2013.00104. eCollection 2013.

Skin is the largest organ of the human body and plays a key role in protecting the individual from external insults. The barrier function of the skin is performed primarily by the epidermis, a self-renewing stratified squamous epithelium composed...

Hormonal control of cardiac regenerative potential.

Endocrine connections

Amram AV, Cutie S, Huang GN.
PMID: 33320107
Endocr Connect. 2021 Jan;10(1):R25-R35. doi: 10.1530/EC-20-0503.

Research conducted across phylogeny on cardiac regenerative responses following heart injury implicates endocrine signaling as a pivotal regulator of both cardiomyocyte proliferation and heart regeneration. Three prominently studied endocrine factors are thyroid hormone, vitamin D, and glucocorticoids, which canonically...

Structures of Endocrine-Disrupting Chemicals Correlate with the Activation of 12 Classic Nuclear Receptors.

Environmental science & technology

Tan H, Chen Q, Hong H, Benfenati E, Gini GC, Zhang X, Yu H, Shi W.
PMID: 34859678
Environ Sci Technol. 2021 Dec 21;55(24):16552-16562. doi: 10.1021/acs.est.1c04997. Epub 2021 Dec 03.

Endocrine-disrupting chemicals (EDCs) can inadvertently interact with 12 classic nuclear receptors (NRs) that disrupt the endocrine system and cause adverse effects. There is no widely accepted understanding about what structural features make thousands of EDCs able to activate different...

Best Achievements in Translational and Basic Thyroidology in 2020.

Endocrinology and metabolism (Seoul, Korea)

Cho SW, Park YJ.
PMID: 33677924
Endocrinol Metab (Seoul). 2021 Feb;36(1):36-40. doi: 10.3803/EnM.2021.104. Epub 2021 Feb 24.

This review discusses articles published in 2020 that presented noteworthy achievements in translational and basic thyroidology. Previously unresolved questions about thyroid hormone receptor actions and signaling mechanisms were answered using various novel in vitro and in vivo models. Using...

Thyroid Hormone Resistance due to a Novel De Novo Mutation in Thyroid Hormone Receptor Alpha: First Case Report from the Middle East and North Africa.

Oman medical journal

Al Shidhani A, Ullah I, AlSaffar H, Al Kindi A, Al Nabhani H, Al Yaarubi S.
PMID: 33628462
Oman Med J. 2021 Jan 31;36(1):e226. doi: 10.5001/omj.2021.20. eCollection 2021 Jan.

The physiological actions of thyroid hormone (TH) are mediated through TH alpha and TH beta receptors. Resistance to TH (RTH) is characterized by a lack of peripheral tissues' response to the active form of TH. TH receptor beta has...

Thrombosis in Thyroid Cancer.

International journal of endocrinology and metabolism

Ordookhani A, Motazedi A, Burman KD.
PMID: 29696039
Int J Endocrinol Metab. 2017 Oct 31;16(1):e57897. doi: 10.5812/ijem.57897. eCollection 2018 Jan.

BACKGROUND: The number of studies on venous thromboembolism (VTE) and thyroid cancer is very scarce and existing data are contradictory. This paper reviews VTE in thyroid cancer.METHODS: The following words were used for a comprehensive literature review using MEDLINE...

Lipid Metabolism Alteration by Endocrine Disruptors in Animal Models: An Overview.

Frontiers in endocrinology

Maradonna F, Carnevali O.
PMID: 30467492
Front Endocrinol (Lausanne). 2018 Nov 08;9:654. doi: 10.3389/fendo.2018.00654. eCollection 2018.

Exposure to potential Endocrine Disrupting Chemicals (EDCs) pose a documented risk to both wildlife and human health. Many studies so far described declining sperm counts, genital malformations, early puberty onset, highlighting the negative impact on reproduction caused by the...

Structures of Endocrine-Disrupting Chemicals Correlate with the Activation of 12 Classic Nuclear Receptors.

Environmental science & technology

Tan H, Chen Q, Hong H, Benfenati E, Gini GC, Zhang X, Yu H, Shi W.
PMID: 34859678
Environ Sci Technol. 2021 Dec 03; doi: 10.1021/acs.est.1c04997. Epub 2021 Dec 03.

Endocrine-disrupting chemicals (EDCs) can inadvertently interact with 12 classic nuclear receptors (NRs) that disrupt the endocrine system and cause adverse effects. There is no widely accepted understanding about what structural features make thousands of EDCs able to activate different...

Showing 1 to 12 of 12 entries