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Showing 1 to 12 of 52 entries
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Simultaneous Quantification of 11 Constituents in Wuji Pill Using Ultra Performance Liquid Chromatography Coupled With a Triple Quadrupole Electrospray Tandem Mass Spectrometry.

Journal of chromatographic science

Tian T, Jin Y, Ma Y, Xie W, Xu H, Du Y.
PMID: 26363492
J Chromatogr Sci. 2016 Feb;54(2):237-45. doi: 10.1093/chromsci/bmv140. Epub 2015 Sep 12.

An ultra performance liquid chromatography coupled with a triple quadrupole electrospray tandem mass spectrometry (UPLC-MS-MS) method was developed for analyzing and identifying the constituents of 11 compounds including berberine, epiberberine, berberrubine, jatrorrhizine, coptisine, palmatine, evodiamine, rutaecarpine, limonin, paeoniflorin and...

Fragmentation pathways and structural characterization of 14 nerve agent compounds by electrospray ionization tandem mass spectrometry.

Journal of analytical toxicology

Housman KJ, Swift AT, Oyler JM.
PMID: 25519457
J Anal Toxicol. 2015 Mar;39(2):96-105. doi: 10.1093/jat/bku135. Epub 2014 Dec 16.

Organophosphate nerve agents (OPNAs) are some of the most widely used and proliferated chemical warfare agents. As evidenced by recent events in Syria, these compounds remain a serious military and terrorist threat to human health because of their toxicity...

Isolation, Chemical Fingerprinting and Simultaneous Quantification of Four Compounds from Tanacetum gracile Using a Validated HPLC-ESI-QTOF-Mass Spectrometry Method.

Journal of chromatographic science

Sharma N, Kumar C, Dutt P, Gupta S, Satti NK, Chandra S, Kitchlu S, Paul S, Vishwakarma RA, Verma MK.
PMID: 26951542
J Chromatogr Sci. 2016 May-Jun;54(5):796-804. doi: 10.1093/chromsci/bmw013. Epub 2016 Mar 06.

The present study was conducted to carry out the phytochemical investigation of Tanacetum gracile Hook. f. & Thomson and to develop a method for the simultaneous quantification of the isolated compounds in the extracts ofT. gracile growing in different...

Ambient ionization MS for bioanalysis: recent developments and challenges.

Bioanalysis

Takyi-Williams J, Liu CF, Tang K.
PMID: 26295990
Bioanalysis. 2015;7(15):1901-23. doi: 10.4155/bio.15.116.

Ambient ionization MS has become very popular in analytical science and has now evolved as an effective analytical tool in metabolomics, biological tissue imaging, protein and small molecule drug analysis, where biological samples are probed in a rapid and...

Effective 2D-RPLC/RPLC enrichment and separation of micro-components from Hedyotis diffusa Willd. and characterization by using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.

Journal of pharmaceutical and biomedical analysis

Li C, Zhao Y, Guo Z, Zhang X, Xue X, Liang X.
PMID: 25061712
J Pharm Biomed Anal. 2014 Oct;99:35-44. doi: 10.1016/j.jpba.2014.06.020. Epub 2014 Jul 09.

An effective method aiming at enrichment and analysis of micro-components in traditional Chinese medicine (TCM) was developed. One fraction (fraction E) from the extract of Hedyotis diffusa Willd. was selected as test sample, which was isolated by using the...

Supercritical fluid chromatography coupled to electrospray mass spectrometry: a powerful tool for the analysis of chiral mixtures.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Garzotti M, Hamdan M.
PMID: 12013244
J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Apr 25;770(1):53-61. doi: 10.1016/s1570-0232(01)00582-7.

Supercritical fluid chromatography coupled to a hybrid mass spectrometer (Q-Tof2) equipped with electrospray ion source has been used to separate and characterise a wide range of pharmaceutical racemates. We have chosen diverse molecular structures to demonstrate the potential of...

Polarity switching accurate mass measurement of pharmaceutical samples using desorption electrospray ionization and a dual ion source interfaced to an orthogonal acceleration time-of-flight mass spectrometer.

Analytical chemistry

Williams JP, Lock R, Patel VJ, Scrivens JH.
PMID: 17073410
Anal Chem. 2006 Nov 01;78(21):7440-5. doi: 10.1021/ac0609125.

A novel approach for the rapid, accurate mass analysis of pharmaceutical solid, liquid, and cream formulations using desorption electrospray ionization (DESI) is described. The method is based on polarity switching and real-time accurate mass measurement in an orthogonal acceleration...

Electrospray ionization mass spectrometry of uniform and mixed monolayer nanoparticles: Au25[S(CH2)2Ph]18 and Au25[S(CH2)2Ph]18-x(SR)x.

Journal of the American Chemical Society

Tracy JB, Crowe MC, Parker JF, Hampe O, Fields-Zinna CA, Dass A, Murray RW.
PMID: 18034488
J Am Chem Soc. 2007 Dec 26;129(51):16209-15. doi: 10.1021/ja076621a. Epub 2007 Nov 23.

New approaches to electrospray ionization mass spectrometry (ESI-MS)-with exact compositional assignments-of small (Au25) nanoparticles with uniform and mixed protecting organothiolate monolayers are described. The results expand the scope of analysis and reveal a rich chemistry of ionization behavior. ESI-MS...

Electrospray ionization from a gap with adjustable width.

Rapid communications in mass spectrometry : RCM

Ek P, Sjödahl J, Roeraade J.
PMID: 17016803
Rapid Commun Mass Spectrom. 2006;20(21):3176-82. doi: 10.1002/rcm.2710.

In this paper, we present a new concept for electrospray ionization mass spectrometry, where the sample is applied in a gap which is formed between the edges of two triangular-shaped tips. The size of the spray orifice can be...

When one chip is not enough: augmenting the validity of SELDI-TOF proteomic profiles of clinical specimens.

Lab on a chip

Kristina G, Radomir P, Eva B, Lenka D, Radek L, Rostislav V, Borivoj V, Dalibor V.
PMID: 19294317
Lab Chip. 2009 Apr 07;9(7):1014-7. doi: 10.1039/b815503h. Epub 2009 Jan 15.

To improve recovery, selectivity and reproducibility of SELDI-TOF analyses, we found it necessary to modify manufacturer's recommended protocols on sample and chip preparation. To yield reproducible denaturing conditions we verified concentrations of denaturing, reducing and lipid-solubilizing agents. We improved...

Synchronized dual-polarity electrospray ionization mass spectrometry.

Journal of the American Society for Mass Spectrometry

Chen HK, Chang CK, Wu CC, Huang MC, Wang YS.
PMID: 19775909
J Am Soc Mass Spectrom. 2009 Dec;20(12):2254-7. doi: 10.1016/j.jasms.2009.08.014. Epub 2009 Aug 28.

This work describes the synchronized dual-polarity (DP) electrospray ionization (ESI) method and demonstrates the first DP ESI mass spectra obtained using two mass spectrometers. Stable double Taylor cones were produced by applying two counter electric voltages with opposite polarities...

Computational mass spectrometry for metabolomics: identification of metabolites and small molecules.

Analytical and bioanalytical chemistry

Neumann S, Böcker S.
PMID: 20936272
Anal Bioanal Chem. 2010 Dec;398(7):2779-88. doi: 10.1007/s00216-010-4142-5. Epub 2010 Oct 09.

The identification of compounds from mass spectrometry (MS) data is still seen as a major bottleneck in the interpretation of MS data. This is particularly the case for the identification of small compounds such as metabolites, where until recently...

Showing 1 to 12 of 52 entries