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Showing 13 to 24 of 69 entries
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The Impact of Malaria on Liver Enzymes: A Retrospective Cohort Study (2010-2017).

Open forum infectious diseases

Cheaveau J, Marasinghe D, Akakpo S, Deardon R, Naugler C, Chin A, Pillai DR.
PMID: 31263731
Open Forum Infect Dis. 2019 May 16;6(6):ofz234. doi: 10.1093/ofid/ofz234. eCollection 2019 Jun.

BACKGROUND: It is unclear if malaria causes deranged liver enzymes. This has implications both in clinical practice and in research, particularly for antimalarial drug development.METHOD: We performed a retrospective cohort study of returning travelers (n = 4548) who underwent...

Biochemical and Histopathological Evaluation of Graphene Oxide in Sprague-Dawley Rats.

Austin journal of environmental toxicology

Patlolla AK, Rondalph J, Tchounwou PB.
PMID: 29503980
Austin J Environ Toxicol. 2017;3(1). Epub 2017 Dec 07.

Graphene and its derivatives are promising material for important biomedical applications due to their versatility. A detailed comprehensive study of the toxicity of these materials is required in context with the prospective use in biological setting. We investigated toxicity...

The Correlation Between Serum Adipokines and Liver Cell Damage in Non-Alcoholic Fatty Liver Disease.

Hepatitis monthly

Jamali R, Hatami N, Kosari F.
PMID: 27313636
Hepat Mon. 2016 Apr 20;16(5):e37412. doi: 10.5812/hepatmon.37412. eCollection 2016 May.

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a common cause of chronic hepatitis, which can lead to cirrhosis and hepatocellular carcinoma.OBJECTIVES: The aim of the study was to evaluate the correlation between serum adipocytokines and the histologic findings of...

Screening for hepatitis C in average and high-risk populations of Qatar using rapid point-of-care testing.

United European gastroenterology journal

Sharma M, Al Kaabi S, John AK, Al Dweik N, Ullah Wani H, Babu Thandassary R, Derbala MF, Al Ejji K, Sultan K, Pasic F, Al Mohannadi M, Yacoub R, Butt MT, Singh R.
PMID: 26279845
United European Gastroenterol J. 2015 Aug;3(4):364-70. doi: 10.1177/2050640615580725.

BACKGROUND: Screening for hepatitis C has been found to be beneficial in high-risk individuals and 'baby boomers'.OBJECTIVE: Our aim was to screen for hepatitis C in average and high-risk individuals and compare the disease characteristics and response to treatment...

Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model.

Journal of ethnopharmacology

Xu Z, Lin S, Tong Z, Chen S, Cao Y, Li Q, Jiang Y, Cai W, Tong Y, Zahra BS, Wang P.
PMID: 34848360
J Ethnopharmacol. 2022 Mar 01;285:114873. doi: 10.1016/j.jep.2021.114873. Epub 2021 Nov 27.

ETHNOPHARMACOLOGICAL RELEVANCE: Traditional Chinese medicine considers that the etiology and pathogenesis of non-alcoholic fatty liver disease (NAFLD) are related to liver depression and qi stagnation. Saffron and its active ingredient, crocetin (CCT), are used for the treatment of metabolic...

COVID-19-Induced Hepatic Injury: A Systematic Review and Meta-Analysis.

Cureus

Abdulla S, Hussain A, Azim D, Abduallah EH, Elawamy H, Nasim S, Kumar S, Naveed H.
PMID: 33194489
Cureus. 2020 Oct 13;12(10):e10923. doi: 10.7759/cureus.10923.

Background The current pandemic of the novel coronavirus disease (COVID-19) is a global health challenge. Pulmonary dysfunction is the main outcome of COVID-19 infection. In critically ill patients, however, liver complications have also been reported. Thus, we conducted a...

Serum alanine aminotransferase levels are closely associated with metabolic disturbances in apparently healthy young adolescents independent of obesity.

Korean journal of pediatrics

Kim KE, Baek KS, Han S, Kim JH, Shin YH.
PMID: 30477286
Korean J Pediatr. 2019 Feb;62(2):48-54. doi: 10.3345/kjp.2018.06639. Epub 2018 Nov 23.

PURPOSE: Liver metabolism plays a pivotal role in the development of metabolic disorders. We aimed to investigate the clinical and laboratory risk factors associated with alanine aminotransferase (ALT) levels in young adolescents from an urban population in Korea.METHODS: A...

Potential effects of dietary seaweeds mixture on the growth performance, antioxidant status, immunity response, and resistance of striped catfish (Pangasianodon hypophthalmus) against Aeromonas hydrophila infection.

Fish & shellfish immunology

Abdelhamid AF, Ayoub HF, Abd El-Gawad EA, Abdelghany MF, Abdel-Tawwab M.
PMID: 34601138
Fish Shellfish Immunol. 2021 Dec;119:76-83. doi: 10.1016/j.fsi.2021.09.043. Epub 2021 Oct 01.

Striped catfish (Pangasianodon hypophthalmus) is one of the important fish species in the world, which is widely cultured in several countries worldwide including Egypt. Aeromonas hydrophila infection showed a high prevalence in the farmed striped catfish negatively affecting its...

Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model.

Journal of ethnopharmacology

Xu Z, Lin S, Tong Z, Chen S, Cao Y, Li Q, Jiang Y, Cai W, Tong Y, Zahra BS, Wang P.
PMID: 34848360
J Ethnopharmacol. 2021 Nov 27;285:114873. doi: 10.1016/j.jep.2021.114873. Epub 2021 Nov 27.

ETHNOPHARMACOLOGICAL RELEVANCE: Traditional Chinese medicine considers that the etiology and pathogenesis of non-alcoholic fatty liver disease (NAFLD) are related to liver depression and qi stagnation. Saffron and its active ingredient, crocetin (CCT), are used for the treatment of metabolic...

Increased Visit-to-Visit Liver Enzyme Variability Is Associated with Incident Diabetes: A Community-Based 12-Year Prospective Cohort Study.

Diabetes & metabolism journal

Bang K, Jun JE, Jeong IK, Ahn KJ, Chung HY, Hwang YC.
PMID: 33725763
Diabetes Metab J. 2021 Nov;45(6):890-898. doi: 10.4093/dmj.2020.0208. Epub 2021 Mar 17.

BACKGROUND: Fatty liver and/or increased liver enzyme values have been reported to be associated with incident diabetes. We sought to determine whether increased visit-to-visit liver enzyme variability is associated with incident diabetes.METHODS: Study participants were recruited from the Korean...

Lycopene alleviates hepatic ischemia reperfusion injury via the Nrf2/HO-1 pathway mediated NLRP3 inflammasome inhibition in Kupffer cells.

Annals of translational medicine

Xue R, Qiu J, Wei S, Liu M, Wang Q, Wang P, Sha B, Wang H, Shi Y, Zhou J, Rao J, Lu L.
PMID: 33987329
Ann Transl Med. 2021 Apr;9(8):631. doi: 10.21037/atm-20-7084.

BACKGROUND: Lycopene is a naturally occurring carotenoid found in many fruits and vegetables, which has antioxidant effects. Although lycopene's protective effect has been observed on ischemia reperfusion (IR) injury in different organs, the effect of lycopene on Kupffer cells...

α-Glutathione S-Transferase: A New Biomarker for Liver Injury?.

The journal of applied laboratory medicine

Maina I, Rule JA, Wians FH, Poirier M, Grant L, Lee WM.
PMID: 33626782
J Appl Lab Med. 2016 Sep 01;1(2):119-128. doi: 10.1373/jalm.2016.020412.

BACKGROUND: Serum alanine and aspartate aminotransferases (ALT/AST) have been the gold standard for detection and quantification of liver injury for over 6 decades, but have relatively long half-lives (T½) (literature estimates approximately 17 and 47 h, respectively) and thus...

Showing 13 to 24 of 69 entries