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Pathways to polyploidy: indications of a female triploid bridge in the alpine species .

Plant systematics and evolution = Entwicklungsgeschichte und Systematik der Pflanzen

Schinkel CCF, Kirchheimer B, Dullinger S, Geelen D, De Storme N, Hörandl E.
PMID: 29081576
Plant Syst Evol. 2017;303(8):1093-1108. doi: 10.1007/s00606-017-1435-6. Epub 2017 Jul 06.

Polyploidy is one of the most important evolutionary processes in plants. In natural populations, polyploids usually emerge from unreduced gametes which either fuse with reduced ones, resulting in triploid offspring (triploid bridge), or with other unreduced gametes, resulting in...

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Schinkel CCF, Kirchheimer B, Dullinger S, et al. Pathways to polyploidy: indications of a female triploid bridge in the alpine species . Plant Syst Evol. 2017;303(8):1093-1108doi: 10.1007/s00606-017-1435-6.
Schinkel, C. C. F., Kirchheimer, B., Dullinger, S., Geelen, D., De Storme, N., & Hörandl, E. (2017). Pathways to polyploidy: indications of a female triploid bridge in the alpine species . Plant systematics and evolution = Entwicklungsgeschichte und Systematik der Pflanzen, 303(8), 1093-1108. https://doi.org/10.1007/s00606-017-1435-6
Schinkel, Christoph C F, et al. "Pathways to polyploidy: indications of a female triploid bridge in the alpine species ." Plant systematics and evolution = Entwicklungsgeschichte und Systematik der Pflanzen vol. 303,8 (2017): 1093-1108. doi: https://doi.org/10.1007/s00606-017-1435-6
Schinkel CCF, Kirchheimer B, Dullinger S, Geelen D, De Storme N, Hörandl E. Pathways to polyploidy: indications of a female triploid bridge in the alpine species . Plant Syst Evol. 2017;303(8):1093-1108. doi: 10.1007/s00606-017-1435-6. Epub 2017 Jul 06. PMID: 29081576; PMCID: PMC5640749.
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The CYP2C9 polymorphism: from enzyme kinetics to clinical dose recommendations.

Personalized medicine

Kirchheiner J, Tsahuridu M, Jabrane W, Roots I, Brockmöller J.
PMID: 29793229
Per Med. 2004 Dec;1(1):63-84. doi: 10.1517/17410541.1.1.63.

CYP2C9 is the major human enzyme of the cytochrome P450 2C subfamily and metabolizes approximately 10% of all therapeutically relevant drugs. Two inherited SNPs termed CYP2C9*2 (Arg144Cys) and *3 (Ile359Leu) are known to affect catalytic function. Numerous rare or...

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Kirchheiner J, Tsahuridu M, Jabrane W, et al. The CYP2C9 polymorphism: from enzyme kinetics to clinical dose recommendations. Per Med. 2004;1(1):63-84doi: 10.1517/17410541.1.1.63.
Kirchheiner, J., Tsahuridu, M., Jabrane, W., Roots, I., & Brockmöller, J. (2004). The CYP2C9 polymorphism: from enzyme kinetics to clinical dose recommendations. Personalized medicine, 1(1), 63-84. https://doi.org/10.1517/17410541.1.1.63
Kirchheiner, Julia, et al. "The CYP2C9 polymorphism: from enzyme kinetics to clinical dose recommendations." Personalized medicine vol. 1,1 (2004): 63-84. doi: https://doi.org/10.1517/17410541.1.1.63
Kirchheiner J, Tsahuridu M, Jabrane W, Roots I, Brockmöller J. The CYP2C9 polymorphism: from enzyme kinetics to clinical dose recommendations. Per Med. 2004 Dec;1(1):63-84. doi: 10.1517/17410541.1.1.63. PMID: 29793229.
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Risk Factors for Late Persistent Fatigue After Chemoradiotherapy in Patients With Locally Advanced Cervical Cancer: An Analysis From the EMBRACE-I Study.

International journal of radiation oncology, biology, physics

Smet S, Spampinato S, Pötter R, Jürgenliemk-Schulz IM, Nout RA, Chargari C, Mahantshetty U, Sturdza A, Segedin B, Bruheim K, Hoskin P, Rai B, Huang F, Cooper R, Van der Steen-Banasik E, Sundset M, Van Limbergen E, Tan LT, Lutgens LCHW, Villafranca E, Pieters BR, Tanderup K, Kirchheiner K.
PMID: 34838868
Int J Radiat Oncol Biol Phys. 2021 Nov 25; doi: 10.1016/j.ijrobp.2021.11.022. Epub 2021 Nov 25.

PURPOSE: This study aimed to evaluate patient- and treatment-related risk factors for late persistent fatigue within the prospective, multicenter EMBRACE-I study.METHODS AND MATERIALS: Fatigue was prospectively assessed (Common Terminology Criteria for Adverse Events, version 3) at baseline and during...

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Smet S, Spampinato S, Pötter R, et al. Risk Factors for Late Persistent Fatigue After Chemoradiotherapy in Patients With Locally Advanced Cervical Cancer: An Analysis From the EMBRACE-I Study. Int J Radiat Oncol Biol Phys. 2021;doi: 10.1016/j.ijrobp.2021.11.022.
Smet, S., Spampinato, S., Pötter, R., Jürgenliemk-Schulz, I. M., Nout, R. A., Chargari, C., Mahantshetty, U., Sturdza, A., Segedin, B., Bruheim, K., Hoskin, P., Rai, B., Huang, F., Cooper, R., Van der Steen-Banasik, E., Sundset, M., Van Limbergen, E., Tan, L. T., Lutgens, L. C. H. W., Villafranca, E., Pieters, B. R., Tanderup, K., Kirchheiner, K. (2021). Risk Factors for Late Persistent Fatigue After Chemoradiotherapy in Patients With Locally Advanced Cervical Cancer: An Analysis From the EMBRACE-I Study. International journal of radiation oncology, biology, physics, . https://doi.org/10.1016/j.ijrobp.2021.11.022
Smet, Stéphanie, et al. "Risk Factors for Late Persistent Fatigue After Chemoradiotherapy in Patients With Locally Advanced Cervical Cancer: An Analysis From the EMBRACE-I Study." International journal of radiation oncology, biology, physics vol. (2021). doi: https://doi.org/10.1016/j.ijrobp.2021.11.022
Smet S, Spampinato S, Pötter R, Jürgenliemk-Schulz IM, Nout RA, Chargari C, Mahantshetty U, Sturdza A, Segedin B, Bruheim K, Hoskin P, Rai B, Huang F, Cooper R, Van der Steen-Banasik E, Sundset M, Van Limbergen E, Tan LT, Lutgens LCHW, Villafranca E, Pieters BR, Tanderup K, Kirchheiner K. Risk Factors for Late Persistent Fatigue After Chemoradiotherapy in Patients With Locally Advanced Cervical Cancer: An Analysis From the EMBRACE-I Study. Int J Radiat Oncol Biol Phys. 2021 Nov 25; doi: 10.1016/j.ijrobp.2021.11.022. Epub 2021 Nov 25. PMID: 34838868.
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Impact of Vaginal Symptoms and Hormonal Replacement Therapy on Sexual Outcomes After Definitive Chemoradiotherapy in Patients With Locally Advanced Cervical Cancer: Results from the EMBRACE-I Study.

International journal of radiation oncology, biology, physics

Kirchheiner K, Smet S, Jürgenliemk-Schulz IM, Haie-Meder C, Chargari C, Lindegaard JC, Fokdal LU, Spampinato S, Schmid MP, Sturdza A, Mahantshetty U, Segedin B, Bruheim K, Rai B, Cooper R, Van der Steen-Banasik E, Wiebe E, Sundset M, van Limbergen E, Villafranca E, Westerveld H, Tan LT, Pötter R, Tanderup K, Nout RA.
PMID: 34478833
Int J Radiat Oncol Biol Phys. 2022 Feb 01;112(2):400-413. doi: 10.1016/j.ijrobp.2021.08.036. Epub 2021 Sep 01.

PURPOSE: To evaluate patient-reported sexual outcomes after chemoradiation therapy and image-guided adaptive brachytherapy for locally advanced cervical cancer in the observational, prospective, multicenter EMBRACE-I study.METHODS AND MATERIALS: Sexual outcomes were assessed prospectively with the European Organization for Research and...

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Kirchheiner K, Smet S, Jürgenliemk-Schulz IM, et al. Impact of Vaginal Symptoms and Hormonal Replacement Therapy on Sexual Outcomes After Definitive Chemoradiotherapy in Patients With Locally Advanced Cervical Cancer: Results from the EMBRACE-I Study. Int J Radiat Oncol Biol Phys. 2021;112(2):400-413doi: 10.1016/j.ijrobp.2021.08.036.
Kirchheiner, K., Smet, S., Jürgenliemk-Schulz, I. M., Haie-Meder, C., Chargari, C., Lindegaard, J. C., Fokdal, L. U., Spampinato, S., Schmid, M. P., Sturdza, A., Mahantshetty, U., Segedin, B., Bruheim, K., Rai, B., Cooper, R., Van der Steen-Banasik, E., Wiebe, E., Sundset, M., van Limbergen, E., Villafranca, E., Westerveld, H., Tan, L. T., Pötter, R., Tanderup, K., Nout, R. A. (2022). Impact of Vaginal Symptoms and Hormonal Replacement Therapy on Sexual Outcomes After Definitive Chemoradiotherapy in Patients With Locally Advanced Cervical Cancer: Results from the EMBRACE-I Study. International journal of radiation oncology, biology, physics, 112(2), 400-413. https://doi.org/10.1016/j.ijrobp.2021.08.036
Kirchheiner, Kathrin, et al. "Impact of Vaginal Symptoms and Hormonal Replacement Therapy on Sexual Outcomes After Definitive Chemoradiotherapy in Patients With Locally Advanced Cervical Cancer: Results from the EMBRACE-I Study." International journal of radiation oncology, biology, physics vol. 112,2 (2022): 400-413. doi: https://doi.org/10.1016/j.ijrobp.2021.08.036
Kirchheiner K, Smet S, Jürgenliemk-Schulz IM, Haie-Meder C, Chargari C, Lindegaard JC, Fokdal LU, Spampinato S, Schmid MP, Sturdza A, Mahantshetty U, Segedin B, Bruheim K, Rai B, Cooper R, Van der Steen-Banasik E, Wiebe E, Sundset M, van Limbergen E, Villafranca E, Westerveld H, Tan LT, Pötter R, Tanderup K, Nout RA. Impact of Vaginal Symptoms and Hormonal Replacement Therapy on Sexual Outcomes After Definitive Chemoradiotherapy in Patients With Locally Advanced Cervical Cancer: Results from the EMBRACE-I Study. Int J Radiat Oncol Biol Phys. 2022 Feb 01;112(2):400-413. doi: 10.1016/j.ijrobp.2021.08.036. Epub 2021 Sep 01. PMID: 34478833.
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Risk factors for nodal failure after radiochemotherapy and image guided brachytherapy in locally advanced cervical cancer: An EMBRACE analysis.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Peters M, de Leeuw AAC, Nomden CN, Tanderup K, Kirchheiner K, Lindegaard JC, Kirisits C, Haie-Meder C, Sturdza A, Fokdal L, Mahantshetty U, Hoskin P, Segedin B, Bruheim K, Rai B, Huang F, Cooper R, van der Steen-Banasik E, van Limbergen E, Pieters BR, Tan LT, van Rossum PSN, Nesvacil N, Nout R, Schmid MP, Pötter R, Jürgenliemk-Schulz IM.
PMID: 34480958
Radiother Oncol. 2021 Oct;163:150-158. doi: 10.1016/j.radonc.2021.08.020. Epub 2021 Sep 02.

OBJECTIVE: To assess risk factors for nodal failure (NF) after definitive (chemo)radiotherapy and image-guided brachytherapy for locally advanced cervical cancer (LACC) for patients treated in the EMBRACE I study.MATERIALS AND METHODS: Data for pelvic NF and para-aortic (PAO) NF...

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Peters M, de Leeuw AAC, Nomden CN, et al. Risk factors for nodal failure after radiochemotherapy and image guided brachytherapy in locally advanced cervical cancer: An EMBRACE analysis. Radiother Oncol. 2021;163:150-158doi: 10.1016/j.radonc.2021.08.020.
Peters, M., de Leeuw, A. A. C., Nomden, C. N., Tanderup, K., Kirchheiner, K., Lindegaard, J. C., Kirisits, C., Haie-Meder, C., Sturdza, A., Fokdal, L., Mahantshetty, U., Hoskin, P., Segedin, B., Bruheim, K., Rai, B., Huang, F., Cooper, R., van der Steen-Banasik, E., van Limbergen, E., Pieters, B. R., Tan, L. T., van Rossum, P. S. N., Nesvacil, N., Nout, R., Schmid, M. P., Pötter, R., Jürgenliemk-Schulz, I. M. (2021). Risk factors for nodal failure after radiochemotherapy and image guided brachytherapy in locally advanced cervical cancer: An EMBRACE analysis. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 163150-158. https://doi.org/10.1016/j.radonc.2021.08.020
Peters, Max, et al. "Risk factors for nodal failure after radiochemotherapy and image guided brachytherapy in locally advanced cervical cancer: An EMBRACE analysis." Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology vol. 163 (2021): 150-158. doi: https://doi.org/10.1016/j.radonc.2021.08.020
Peters M, de Leeuw AAC, Nomden CN, Tanderup K, Kirchheiner K, Lindegaard JC, Kirisits C, Haie-Meder C, Sturdza A, Fokdal L, Mahantshetty U, Hoskin P, Segedin B, Bruheim K, Rai B, Huang F, Cooper R, van der Steen-Banasik E, van Limbergen E, Pieters BR, Tan LT, van Rossum PSN, Nesvacil N, Nout R, Schmid MP, Pötter R, Jürgenliemk-Schulz IM. Risk factors for nodal failure after radiochemotherapy and image guided brachytherapy in locally advanced cervical cancer: An EMBRACE analysis. Radiother Oncol. 2021 Oct;163:150-158. doi: 10.1016/j.radonc.2021.08.020. Epub 2021 Sep 02. PMID: 34480958.
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Three or less? Decision making for or against selective reduction and psychological outcome in forty women with a triplet pregnancy.

Journal of psychosomatic obstetrics and gynaecology

Leithner K, Stammler-Safar M, Springer S, Kirchheiner K, Hilger E.
PMID: 32312137
J Psychosom Obstet Gynaecol. 2021 Dec;42(4):286-292. doi: 10.1080/0167482X.2020.1750005. Epub 2020 Apr 21.

OBJECTIVES: The aim of the study was to investigate decision making for or against multifetal pregnancy reduction (MFPR) and psychological outcome in women with a triplet pregnancy.METHODS: We investigated medical and sociodemographic variables and characteristics of the decision process...

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Leithner K, Stammler-Safar M, Springer S, et al. Three or less? Decision making for or against selective reduction and psychological outcome in forty women with a triplet pregnancy. J Psychosom Obstet Gynaecol. 2020;42(4):286-292doi: 10.1080/0167482X.2020.1750005.
Leithner, K., Stammler-Safar, M., Springer, S., Kirchheiner, K., & Hilger, E. (2021). Three or less? Decision making for or against selective reduction and psychological outcome in forty women with a triplet pregnancy. Journal of psychosomatic obstetrics and gynaecology, 42(4), 286-292. https://doi.org/10.1080/0167482X.2020.1750005
Leithner, Katharina, et al. "Three or less? Decision making for or against selective reduction and psychological outcome in forty women with a triplet pregnancy." Journal of psychosomatic obstetrics and gynaecology vol. 42,4 (2021): 286-292. doi: https://doi.org/10.1080/0167482X.2020.1750005
Leithner K, Stammler-Safar M, Springer S, Kirchheiner K, Hilger E. Three or less? Decision making for or against selective reduction and psychological outcome in forty women with a triplet pregnancy. J Psychosom Obstet Gynaecol. 2021 Dec;42(4):286-292. doi: 10.1080/0167482X.2020.1750005. Epub 2020 Apr 21. PMID: 32312137.
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A matter of scale: apparent niche differentiation of diploid and tetraploid plants may depend on extent and grain of analysis.

Journal of biogeography

Kirchheimer B, Schinkel CC, Dellinger AS, Klatt S, Moser D, Winkler M, Lenoir J, Caccianiga M, Guisan A, Nieto-Lugilde D, Svenning JC, Thuiller W, Vittoz P, Willner W, Zimmermann NE, Hörandl E, Dullinger S.
PMID: 27482126
J Biogeogr. 2016 Mar 22;43(4):716-726. doi: 10.1111/jbi.12663.

AIM: Emerging polyploids may depend on environmental niche shifts for successful establishment. Using the alpine plant LOCATION: European Alps.METHODS: We sampled 12 individuals from each of 102 populations of RESULTS: All comparisons indicate that the niches of the two...

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Kirchheimer B, Schinkel CC, Dellinger AS, et al. A matter of scale: apparent niche differentiation of diploid and tetraploid plants may depend on extent and grain of analysis. J Biogeogr. 2016;43(4):716-726doi: 10.1111/jbi.12663.
Kirchheimer, B., Schinkel, C. C., Dellinger, A. S., Klatt, S., Moser, D., Winkler, M., Lenoir, J., Caccianiga, M., Guisan, A., Nieto-Lugilde, D., Svenning, J. C., Thuiller, W., Vittoz, P., Willner, W., Zimmermann, N. E., Hörandl, E., & Dullinger, S. (2016). A matter of scale: apparent niche differentiation of diploid and tetraploid plants may depend on extent and grain of analysis. Journal of biogeography, 43(4), 716-726. https://doi.org/10.1111/jbi.12663
Kirchheimer, Bernhard, et al. "A matter of scale: apparent niche differentiation of diploid and tetraploid plants may depend on extent and grain of analysis." Journal of biogeography vol. 43,4 (2016): 716-726. doi: https://doi.org/10.1111/jbi.12663
Kirchheimer B, Schinkel CC, Dellinger AS, Klatt S, Moser D, Winkler M, Lenoir J, Caccianiga M, Guisan A, Nieto-Lugilde D, Svenning JC, Thuiller W, Vittoz P, Willner W, Zimmermann NE, Hörandl E, Dullinger S. A matter of scale: apparent niche differentiation of diploid and tetraploid plants may depend on extent and grain of analysis. J Biogeogr. 2016 Mar 22;43(4):716-726. doi: 10.1111/jbi.12663. PMID: 27482126; PMCID: PMC4966631.
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The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies.

Clinical and translational radiation oncology

Pötter R, Tanderup K, Kirisits C, de Leeuw A, Kirchheiner K, Nout R, Tan LT, Haie-Meder C, Mahantshetty U, Segedin B, Hoskin P, Bruheim K, Rai B, Huang F, Van Limbergen E, Schmid M, Nesvacil N, Sturdza A, Fokdal L, Jensen NBK, Georg D, Assenholt M, Seppenwoolde Y, Nomden C, Fortin I, Chopra S, van der Heide U, Rumpold T, Lindegaard JC, Jürgenliemk-Schulz I.
PMID: 29594251
Clin Transl Radiat Oncol. 2018 Jan 11;9:48-60. doi: 10.1016/j.ctro.2018.01.001. eCollection 2018 Feb.

The publication of the GEC-ESTRO recommendations one decade ago was a significant step forward for reaching international consensus on adaptive target definition and dose reporting in image guided adaptive brachytherapy (IGABT) in locally advanced cervical cancer. Since then, IGABT...

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Pötter R, Tanderup K, Kirisits C, et al. The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies. Clin Transl Radiat Oncol. 2018;9:48-60doi: 10.1016/j.ctro.2018.01.001.
Pötter, R., Tanderup, K., Kirisits, C., de Leeuw, A., Kirchheiner, K., Nout, R., Tan, L. T., Haie-Meder, C., Mahantshetty, U., Segedin, B., Hoskin, P., Bruheim, K., Rai, B., Huang, F., Van Limbergen, E., Schmid, M., Nesvacil, N., Sturdza, A., Fokdal, L., Jensen, N. B. K., Georg, D., Assenholt, M., Seppenwoolde, Y., Nomden, C., Fortin, I., Chopra, S., van der Heide, U., Rumpold, T., Lindegaard, J. C., Jürgenliemk-Schulz, I. (2018). The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies. Clinical and translational radiation oncology, 948-60. https://doi.org/10.1016/j.ctro.2018.01.001
Pötter, Richard, et al. "The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies." Clinical and translational radiation oncology vol. 9 (2018): 48-60. doi: https://doi.org/10.1016/j.ctro.2018.01.001
Pötter R, Tanderup K, Kirisits C, de Leeuw A, Kirchheiner K, Nout R, Tan LT, Haie-Meder C, Mahantshetty U, Segedin B, Hoskin P, Bruheim K, Rai B, Huang F, Van Limbergen E, Schmid M, Nesvacil N, Sturdza A, Fokdal L, Jensen NBK, Georg D, Assenholt M, Seppenwoolde Y, Nomden C, Fortin I, Chopra S, van der Heide U, Rumpold T, Lindegaard JC, Jürgenliemk-Schulz I. The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies. Clin Transl Radiat Oncol. 2018 Jan 11;9:48-60. doi: 10.1016/j.ctro.2018.01.001. eCollection 2018 Feb. PMID: 29594251; PMCID: PMC5862686.
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Risk factors for nodal failure after radiochemotherapy and image guided brachytherapy in locally advanced cervical cancer: An EMBRACE analysis.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Peters M, de Leeuw AAC, Nomden CN, Tanderup K, Kirchheiner K, Lindegaard JC, Kirisits C, Haie-Meder C, Sturdza A, Fokdal L, Mahantshetty U, Hoskin P, Segedin B, Bruheim K, Rai B, Huang F, Cooper R, van der Steen-Banasik E, van Limbergen E, Pieters BR, Tan LT, van Rossum PSN, Nesvacil N, Nout R, Schmid MP, Pötter R, Jürgenliemk-Schulz IM.
PMID: 34480958
Radiother Oncol. 2021 Oct;163:150-158. doi: 10.1016/j.radonc.2021.08.020. Epub 2021 Sep 02.

OBJECTIVE: To assess risk factors for nodal failure (NF) after definitive (chemo)radiotherapy and image-guided brachytherapy for locally advanced cervical cancer (LACC) for patients treated in the EMBRACE I study.MATERIALS AND METHODS: Data for pelvic NF and para-aortic (PAO) NF...

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Peters M, de Leeuw AAC, Nomden CN, et al. Risk factors for nodal failure after radiochemotherapy and image guided brachytherapy in locally advanced cervical cancer: An EMBRACE analysis. Radiother Oncol. 2021;163:150-158doi: 10.1016/j.radonc.2021.08.020.
Peters, M., de Leeuw, A. A. C., Nomden, C. N., Tanderup, K., Kirchheiner, K., Lindegaard, J. C., Kirisits, C., Haie-Meder, C., Sturdza, A., Fokdal, L., Mahantshetty, U., Hoskin, P., Segedin, B., Bruheim, K., Rai, B., Huang, F., Cooper, R., van der Steen-Banasik, E., van Limbergen, E., Pieters, B. R., Tan, L. T., van Rossum, P. S. N., Nesvacil, N., Nout, R., Schmid, M. P., Pötter, R., Jürgenliemk-Schulz, I. M. (2021). Risk factors for nodal failure after radiochemotherapy and image guided brachytherapy in locally advanced cervical cancer: An EMBRACE analysis. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 163150-158. https://doi.org/10.1016/j.radonc.2021.08.020
Peters, Max, et al. "Risk factors for nodal failure after radiochemotherapy and image guided brachytherapy in locally advanced cervical cancer: An EMBRACE analysis." Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology vol. 163 (2021): 150-158. doi: https://doi.org/10.1016/j.radonc.2021.08.020
Peters M, de Leeuw AAC, Nomden CN, Tanderup K, Kirchheiner K, Lindegaard JC, Kirisits C, Haie-Meder C, Sturdza A, Fokdal L, Mahantshetty U, Hoskin P, Segedin B, Bruheim K, Rai B, Huang F, Cooper R, van der Steen-Banasik E, van Limbergen E, Pieters BR, Tan LT, van Rossum PSN, Nesvacil N, Nout R, Schmid MP, Pötter R, Jürgenliemk-Schulz IM. Risk factors for nodal failure after radiochemotherapy and image guided brachytherapy in locally advanced cervical cancer: An EMBRACE analysis. Radiother Oncol. 2021 Oct;163:150-158. doi: 10.1016/j.radonc.2021.08.020. Epub 2021 Sep 02. PMID: 34480958.
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Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future.

International journal of radiation oncology, biology, physics

Spampinato S, Jensen NBK, Pötter R, Fokdal LU, Chargari C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Hoskin P, Segedin B, Rai B, Bruheim K, Wiebe E, Van der Steen-Banasik E, Cooper R, Van Limbergen E, Sundset M, Pieters BR, Lutgens LCHW, Tan LT, Villafranca E, Smet S, Jastaniyah N, Nout RA, Kirisits C, Chopra S, Kirchheiner K, Tanderup K, Embrace Collaborative Group.
PMID: 34678431
Int J Radiat Oncol Biol Phys. 2021 Oct 20; doi: 10.1016/j.ijrobp.2021.09.055. Epub 2021 Oct 20.

PURPOSE: The purpose was to evaluate patient- and treatment-related risk factors for physician-assessed and patient-reported gastrointestinal (GI) symptoms after radio(chemo)therapy and image guided adaptive brachytherapy in locally advanced cervical cancer.METHODS AND MATERIALS: Of 1416 patients from the EMBRACE-I study,...

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Spampinato S, Jensen NBK, Pötter R, et al. Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future. Int J Radiat Oncol Biol Phys. 2021;doi: 10.1016/j.ijrobp.2021.09.055.
Spampinato, S., Jensen, N. B. K., Pötter, R., Fokdal, L. U., Chargari, C., Lindegaard, J. C., Schmid, M. P., Sturdza, A., Jürgenliemk-Schulz, I. M., Mahantshetty, U., Hoskin, P., Segedin, B., Rai, B., Bruheim, K., Wiebe, E., Van der Steen-Banasik, E., Cooper, R., Van Limbergen, E., Sundset, M., Pieters, B. R., Lutgens, L. C. H. W., Tan, L. T., Villafranca, E., Smet, S., Jastaniyah, N., Nout, R. A., Kirisits, C., Chopra, S., Kirchheiner, K., Tanderup, K., & Embrace Collaborative Group. (2021). Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future. International journal of radiation oncology, biology, physics, . https://doi.org/10.1016/j.ijrobp.2021.09.055
Spampinato, Sofia, et al. "Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future." International journal of radiation oncology, biology, physics vol. (2021). doi: https://doi.org/10.1016/j.ijrobp.2021.09.055
Spampinato S, Jensen NBK, Pötter R, Fokdal LU, Chargari C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Hoskin P, Segedin B, Rai B, Bruheim K, Wiebe E, Van der Steen-Banasik E, Cooper R, Van Limbergen E, Sundset M, Pieters BR, Lutgens LCHW, Tan LT, Villafranca E, Smet S, Jastaniyah N, Nout RA, Kirisits C, Chopra S, Kirchheiner K, Tanderup K, Embrace Collaborative Group. Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future. Int J Radiat Oncol Biol Phys. 2021 Oct 20; doi: 10.1016/j.ijrobp.2021.09.055. Epub 2021 Oct 20. PMID: 34678431.
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Correlations of polyploidy and apomixis with elevation and associated environmental gradients in an alpine plant.

AoB PLANTS

Schinkel CC, Kirchheimer B, Dellinger AS, Klatt S, Winkler M, Dullinger S, Hörandl E.
PMID: 27594702
AoB Plants. 2016 Oct 27;8. doi: 10.1093/aobpla/plw064. Print 2016.

Apomictic plants expand their geographical distributions more to higher elevations compared to their sexual progenitors. It was so far unclear whether this tendency is related to mode of reproduction itself or represents a side effect of polyploidy. Apomixis is...

Cite
Schinkel CC, Kirchheimer B, Dellinger AS, et al. Correlations of polyploidy and apomixis with elevation and associated environmental gradients in an alpine plant. AoB Plants. 2016;8doi: 10.1093/aobpla/plw064.
Schinkel, C. C., Kirchheimer, B., Dellinger, A. S., Klatt, S., Winkler, M., Dullinger, S., & Hörandl, E. (2016). Correlations of polyploidy and apomixis with elevation and associated environmental gradients in an alpine plant. AoB PLANTS, 8. https://doi.org/10.1093/aobpla/plw064
Schinkel, Christoph C F, et al. "Correlations of polyploidy and apomixis with elevation and associated environmental gradients in an alpine plant." AoB PLANTS vol. 8 (2016). doi: https://doi.org/10.1093/aobpla/plw064
Schinkel CC, Kirchheimer B, Dellinger AS, Klatt S, Winkler M, Dullinger S, Hörandl E. Correlations of polyploidy and apomixis with elevation and associated environmental gradients in an alpine plant. AoB Plants. 2016 Oct 27;8. doi: 10.1093/aobpla/plw064. Print 2016. PMID: 27594702; PMCID: PMC5091893.
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Pharmacogenetics and individualized medicine - bridging the gap between pharmacogenetic research and the patient.

Personalized medicine

Kirchheiner J.
PMID: 29793234
Per Med. 2005 Mar;2(1):37-42. doi: 10.1517/17410541.2.1.37.

A considerable component of the variability seen in drug response or drug disposition has been explained by pharmacogenetic factors. Thus, diagnosing inherited variability in molecules involved in drug response may help to optimize drug therapy and provide more individualized...

Cite
Kirchheiner J. Pharmacogenetics and individualized medicine - bridging the gap between pharmacogenetic research and the patient. Per Med. 2005;2(1):37-42doi: 10.1517/17410541.2.1.37.
Kirchheiner, J. (2005). Pharmacogenetics and individualized medicine - bridging the gap between pharmacogenetic research and the patient. Personalized medicine, 2(1), 37-42. https://doi.org/10.1517/17410541.2.1.37
Kirchheiner, Julia. "Pharmacogenetics and individualized medicine - bridging the gap between pharmacogenetic research and the patient." Personalized medicine vol. 2,1 (2005): 37-42. doi: https://doi.org/10.1517/17410541.2.1.37
Kirchheiner J. Pharmacogenetics and individualized medicine - bridging the gap between pharmacogenetic research and the patient. Per Med. 2005 Mar;2(1):37-42. doi: 10.1517/17410541.2.1.37. PMID: 29793234.
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