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Showing 1 to 12 of 228 entries
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Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting.

Journal of extracellular vesicles

Kooijmans SA, Aleza CG, Roffler SR, van Solinge WW, Vader P, Schiffelers RM.
PMID: 26979463
J Extracell Vesicles. 2016 Mar 14;5:31053. doi: 10.3402/jev.v5.31053. eCollection 2016.

BACKGROUND: Extracellular vesicles (EVs) are attractive candidate drug delivery systems due to their ability to functionally transport biological cargo to recipient cells. However, the apparent lack of target cell specificity of exogenously administered EVs limits their therapeutic applicability. In...

Predicting Contrast-induced Renal Complications in the Catheterization Laboratory.

Interventional cardiology clinics

Kooiman J, Gurm HS.
PMID: 28582222
Interv Cardiol Clin. 2014 Jul;3(3):369-377. doi: 10.1016/j.iccl.2014.03.005. Epub 2014 Jun 28.

Risk scores should undergo 3 analytical phases before they are suitable for adoption in clinical practice, namely, derivation, external validation, and assessment of effect on clinical outcomes of use of the risk score in a so-called impact study. Major...

Light dependence of sexual agglutinability in Chlamydomonas eugametos.

Planta

Kooijman R, Elzenga TJ, de Wildt P, Musgrave A, Schuring F, van den Ende H.
PMID: 24232649
Planta. 1986 Nov;169(3):370-8. doi: 10.1007/BF00392133.

The mating activity of mating-type plus gametes of Chlamydomonas eugametos depends on light. Cells lost their ability to agglutinate with mating-type minus gametes after a dark period of 30 min. They regained their agglutinability after 10 min exposure to...

Association of MRS-Based Vertebral Bone Marrow Fat Fraction with Bone Strength in a Human In Vitro Model.

Journal of osteoporosis

Karampinos DC, Ruschke S, Gordijenko O, Grande Garcia E, Kooijman H, Burgkart R, Rummeny EJ, Bauer JS, Baum T.
PMID: 25969766
J Osteoporos. 2015;2015:152349. doi: 10.1155/2015/152349. Epub 2015 Apr 19.

Bone marrow adiposity has recently gained attention due to its association with bone loss pathophysiology. In this study, ten vertebrae were harvested from fresh human cadavers. Trabecular BMD and microstructure parameters were extracted from MDCT. Bone marrow fat fractions...

Prevalence of 'Candidatus Accumulibacter phosphatis' type II under phosphate limiting conditions.

AMB Express

Welles L, Lopez-Vazquez CM, Hooijmans CM, van Loosdrecht MCM, Brdjanovic D.
PMID: 27376945
AMB Express. 2016 Dec;6(1):44. doi: 10.1186/s13568-016-0214-z. Epub 2016 Jul 04.

P-limitation in enhanced biological phosphorus removal (EBPR) systems fed with acetate, has generally been considered as a condition leading to enrichment of organisms of the genotype' Candidatus Competibacter phosphatis' expressing the glycogen-accumulating organisms (GAO) phenotype. Recent studies have demonstrated...

Impact of Coagulant and Flocculant Addition to an Anaerobic Dynamic Membrane Bioreactor (AnDMBR) Treating Waste-Activated Sludge.

Membranes

Kooijman G, Lopes W, Zhou Z, Guo H, de Kreuk M, Spanjers H, van Lier J.
PMID: 28333092
Membranes (Basel). 2017 Mar 23;7(2). doi: 10.3390/membranes7020018.

In this work, we investigated the effects of flocculation aid (FA) addition to an anaerobic dynamic membrane bioreactor (AnDMBR) (7 L, 35 °C) treating waste-activated sludge (WAS). The experiment consisted of three distinct periods. In period 1 (day 1-86),...

Dithiacrown Ether Substituted Porphyrazines: Synthesis, Single-Crystal Structure, and Control of Aggregation in Solution by Complexation of Transition-Metal Ions.

Inorganic chemistry

van Nostrum CF, Benneker FB, Brussaard H, Kooijman H, Veldman N, Spek AL, Schoonman J, Feiters MC, Nolte RJ.
PMID: 11666270
Inorg Chem. 1996 Feb 14;35(4):959-969. doi: 10.1021/ic950704n.

The synthesis of novel magnesium, copper, and metal-free porphyrazines, peripherally substituted with dithia-7-crown-2 (MPz(7)), dithia-15-crown-5 (MPz(15)), and dithia-18-crown-6 (MPz(18)) macrocycles is reported. These compounds are prepared starting from dicyanoethylene containing crown ethers 3, 2(1), and 2(2), respectively, which contain...

Monodentate sigma-N and Bidentate sigma-N,sigma-N' Coordination of 1,1-Bis((N-p-tolylimino)diphenylphosphoranyl)ethane, CHCH(3)(PPh(2)=NC(6)H(4)-4-CH(3))(2), to Platinum(II).

Inorganic chemistry

Avis MW, Elsevier CJ, Veldman N, Kooijman H, Spek AL.
PMID: 11666367
Inorg Chem. 1996 Mar 13;35(6):1518-1528. doi: 10.1021/ic950748w.

The new ligand, 1,1-bis((N-p-tolylimino)diphenylphosphoranyl)ethane (1,1-BIPE), 1, has been synthesized by means of a Staudinger reaction of 1,1-bis(diphenylphosphino)ethane (1,1-dppe) with 2 equiv of p-tolylazide. Bridge-splitting reactions of Pt(2)Cl(4)(PR(3))(2) with 1 readily afforded sigma-N monodentate complexes, [PtCl(2)(PR(3)){1,1-BIPE-sigmaN}] (2a, PR(3) = PEt(3);...

Hydrogen-Bonded Complexes of Diaminopyridines and Diaminotriazines: Opposite Effect of Acylation on Complex Stabilities.

The Journal of organic chemistry

Beijer FH, Sijbesma RP, Vekemans JA, Meijer EW, Kooijman H, Spek AL.
PMID: 11667479
J Org Chem. 1996 Sep 06;61(18):6371-6380. doi: 10.1021/jo960612v.

The association behavior of several 2,4-diamino-s-triazines, 2,6-diaminopyridines, and their acylated derivatives with uracil derivatives was studied. In solution (1)H-NMR and IR spectroscopy were used, and in the solid state as (co)crystals X-ray diffraction was used. Acylation of 2,6-diaminopyridine leads...

Ladderlike oligomers; intramolecular hydrogen bonding, push-pull character, and electron affinity.

Chemistry (Weinheim an der Bergstrasse, Germany)

Pieterse K, Vekemans JA, Kooijman H, Spek AL, Meijer EW.
PMID: 11192093
Chemistry. 2000 Dec 15;6(24):4597-603. doi: 10.1002/1521-3765(20001215)6:24<4597::aid-chem4597>3.0.co;2-4.

Symmetrical 2,5-bis(2-aminophenyl)pyrazines have been synthesized by application of the Stille coupling strategy. These cotrimers feature three important properties, namely strong intramolecular hydrogen bonding, push-pull character, and high electron affinity. The presence of intramolecular hydrogen bonds has been confirmed by...

[Reliability and accuracy of reported causes of death from cancer. I. Reliability of all cancer reported in the State of Rio de Janeiro, Brazil].

Cadernos de saude publica

Monteiro GT, Koifman RJ, Koifman S.
PMID: 10886923
Cad Saude Publica. 1997;13:39-52.

Mortality records are often used in epidemiological studies, particularly in cancer studies. This paper aims to evaluate reliability and accuracy of cancer mortality data in Rio de Janeiro, Brazil. A systematic random sample of 394 death certificates was obtained...

X-ray crystal structures and conformational analysis of bicyclo[5.3.1]undec-1(11)-enes: twisting versus pyradidalization in anti-bredt olefins.

The Journal of organic chemistry

Wijsman GW, Iglesias GA, de Wolf WH, Beekman MC, Bickelhaupt F, Kooijman H, Spek AL.
PMID: 11312951
J Org Chem. 2001 Feb 23;66(4):1216-27. doi: 10.1021/jo0013195.

The synthesis of several 9,11,11-trihalo[5.3.1]propellanes and their 4-dimethylsila analogues is described. They solvolyze under formation of the corresponding isomeric 7,9,11- trihalobicyclo[5.3.l]undec-1(11)-enes which are "anti-Bredt" olefins with a strained trans double bond in a bridged eight-membered ring; in the presence...

Showing 1 to 12 of 228 entries