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Showing 1 to 12 of 318 entries
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DNA hydroxymethylation age of human blood determined by capillary hydrophilic-interaction liquid chromatography/mass spectrometry.

Clinical epigenetics

Xiong J, Jiang HP, Peng CY, Deng QY, Lan MD, Zeng H, Zheng F, Feng YQ, Yuan BF.
PMID: 26207150
Clin Epigenetics. 2015 Jul 23;7:72. doi: 10.1186/s13148-015-0109-x. eCollection 2015.

BACKGROUND: Aging is a complex phenomenon and characterized by a progressive decline in physiology and function of adult tissues. However, it hasn't been well established of the correlation between aging and global DNA methylation and hydroxymethylation that regulate the...

Contrast-Enhanced Ultrasound for the Characterization of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.

Liver cancer

Liu GJ, Wang W, Lu MD, Xie XY, Xu HX, Xu ZF, Chen LD, Wang Z, Liang JY, Huang Y, Li W, Liu JY.
PMID: 26779444
Liver Cancer. 2015 Dec;4(4):241-52. doi: 10.1159/000367738. Epub 2015 Oct 21.

PURPOSE AND METHODS: The ability of contrast-enhanced ultrasound (CEUS) to differentiate between hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) is still controversial. We reviewed the CEUS imaging of 819 patients (HCC=546, ICC=273) with an established pathological diagnosis. The enhancement...

Consensus on the Prevention, Screening, Early Diagnosis and Treatment of Colorectal Tumors in China: Chinese Society of Gastroenterology, October 14-15, 2011, Shanghai, China.

Gastrointestinal tumors

Fang JY, Zheng S, Jiang B, Lai MD, Fang DC, Han Y, Sheng QJ, Li JN, Chen YX, Gao QY.
PMID: 26672726
Gastrointest Tumors. 2014 Jun;1(2):53-75. doi: 10.1159/000362585. Epub 2014 May 09.

BACKGROUND: Colorectal cancer (CRC) is steadily increasing in China. Colorectal adenoma (CRA) is the most important precancerous disease of CRC. Screening for colorectal tumors can aid early diagnosis. Advances in endoscopic mucosal resection and endoscopic submucosal dissection can aid...

Functional heterogeneity of gut-resident regulatory T cells.

Clinical & translational immunology

Luu M, Steinhoff U, Visekruna A.
PMID: 28983404
Clin Transl Immunology. 2017 Sep 22;6(9):e156. doi: 10.1038/cti.2017.39. eCollection 2017 Sep.

Regulatory T cells (Treg cells) have a central role in the maintenance of intestinal homeostasis by restraining inappropriate immune responses in the healthy gut. Although distinct intestinal immune cell populations have been described to exhibit regulatory activity, several genetic...

Endovascular biopsy: Strategy for analyzing gene expression profiles of individual endothelial cells obtained from human vessels.

Biotechnology reports (Amsterdam, Netherlands)

Sun Z, Lawson DA, Sinclair E, Wang CY, Lai MD, Hetts SW, Higashida RT, Dowd CF, Halbach VV, Werb Z, Su H, Cooke DL.
PMID: 26989654
Biotechnol Rep (Amst). 2015 Sep;7:157-165. doi: 10.1016/j.btre.2015.07.001. Epub 2015 Aug 01.

PURPOSE: To develop a strategy of achieving targeted collection of endothelial cells (ECs) by endovascular methods and analyzing the gene expression profiles of collected single ECs.METHODS AND RESULTS: 134 ECs and 37 leukocytes were collected from four patients' intra-iliac...

Measurement of Retinal Sensitivity on Tablet Devices in Age-Related Macular Degeneration.

Translational vision science & technology

Wu Z, Guymer RH, Jung CJ, Goh JK, Ayton LN, Luu CD, Lawson DJ, Turpin A, McKendrick AM.
PMID: 26175959
Transl Vis Sci Technol. 2015 Jun 30;4(3):13. doi: 10.1167/tvst.4.3.13. eCollection 2015 Jun.

PURPOSE: We compared measurements of central retinal sensitivity on a portable, low-cost tablet device to the established method of microperimetry in age-related macular degeneration (AMD).METHODS: A customized test designed to measure central retinal sensitivity (within the central 1° radius)...

A study of the ameliorating effects of carnitine on hepatic steatosis induced by total parenteral nutrition in rats.

World journal of gastroenterology

Liang LJ, Yin XY, Luo SM, Zheng JF, Lu MD, Huang JF.
PMID: 11819455
World J Gastroenterol. 1999 Aug;5(4):312-315. doi: 10.3748/wjg.v5.i4.312.

AIM:To investigate the effects of carnitine on ameliorating hepatic steatosis induced by total parenteral nutrition (TPN) in animal model.METHODS: Eighteen normal Wistar rats and 19 cirrhotic Wistar rats induced by carbon tetrachloride were randomly divided into three groups, i.e.,...

Reversed-phase HPLC determination of Co(II), Ni(II) and Fe(III) as their 2-(2-thiazolylazo)-5-dimethylaminophenol chelates.

Talanta

Li LY, Gui MD, Zhao YQ.
PMID: 18966206
Talanta. 1995 Jan;42(1):89-92. doi: 10.1016/0039-9140(94)00221-d.

The optimum chromatographic separation conditions for Co(II), Ni(II), and Fe(III) chelates with 2-(2-thiazolylazo)-5-dimethylaminophenol (TAM) were investigated. The compositions of chelates were also determined by the HPLC method and thus the possible structure of chelates was given. A precolumn derivatization...

[Advances in the studies of Reg family].

Yi chuan = Hereditas

Zhang YW, Ding LS, Lai MD.
PMID: 15639940
Yi Chuan. 2003 Sep;25(5):601-6.

Since the first member of Reg gene was discovered in 1988, it has been verified that Reg genes play important roles in diabetes, inflammation and injury, and tumors. More members were cloned and their application in treatment was studied....

Spectroscopic and computational studies on the coordination-driven self-assembly complexes (ZnL)2 and (NiL)2 [L= bis(2,4-dimethyldipyrrin-3-yl)methane].

The journal of physical chemistry. B

Li W, Wang YB, Yang LY, Shan XF, Cai X, Szeghalmi A, Ye Y, Ma JS, Luo MD, Hu J, Kiefer W.
PMID: 17064165
J Phys Chem B. 2006 Nov 02;110(43):21958-65. doi: 10.1021/jp063105i.

FT-IR, FT-Raman and electronic absorption spectroscopies were utilized in conjunction with density functional theory (DFT) calculations to investigate the ground and excited states of self-assembled dinuclear dimeric helicates (ZnL)2 and (NiL)2 [L = bis(2,4-dimethyldipyrrin-3-yl)methane]. These studies afford a detailed...

Solubilization of fish proteins using immobilized microbial cells.

Biotechnology and bioengineering

Venugopal V, Alur MD, Nerkar DP.
PMID: 18588026
Biotechnol Bioeng. 1989 Apr 05;33(9):1098-103. doi: 10.1002/bit.260330904.

Cells of Bacillus megaterium, Aeromonas hydrophila, and Pseudomonas marinoglutinosa were immobilized in calcium alginate. The immobilized cells secreted protease when held in fish meat suspension in water. The enzyme synthesis by the entrapped cells was supported by small amounts...

The effects of DNA formulation and administration route on cancer therapeutic efficacy with xenogenic EGFR DNA vaccine in a lung cancer animal model.

Genetic vaccines and therapy

Lai MD, Yen MC, Lin CM, Tu CF, Wang CC, Lin PS, Yang HJ, Lin CC.
PMID: 19178753
Genet Vaccines Ther. 2009 Jan 30;7:2. doi: 10.1186/1479-0556-7-2.

BACKGROUND: Tyrosine kinase inhibitor gefitinib is effective against lung cancer cells carrying mutant epidermal growth factor receptor (EGFR); however, it is not effective against lung cancer carrying normal EGFR. The breaking of immune tolerance against self epidermal growth factor...

Showing 1 to 12 of 318 entries