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Showing 1 to 12 of 1981 entries
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New Labdane diterpenes from Hedychium yunnanense with cytotoxicity and inhibitory effects on nitric oxide production.

Natural product research

Li YP, Zhao SM, Xu JJ, Zeng GZ, Li Y, Tan NH, Yang Y.
PMID: 26965832
Nat Prod Res. 2016 Dec;30(23):2669-2674. doi: 10.1080/14786419.2016.1143829. Epub 2016 Mar 11.

Two new labdane diterpenes, hedychenoids A (1) and B (2), were isolated from the rhizomes of Hedychium yunnanense, together with four known ones hedychenone (3), forrestin A (4), villosin (5) and calcaratarin C (6). Their structures were determined on...

[Cytotoxic effects of local anesthesia through lidocaine/ropivacaine on human melanoma cell lines].

Revista brasileira de anestesiologia

Kang DK, Zhao LY, Wang HL.
PMID: 27639508
Rev Bras Anestesiol. 2016 Nov - Dec;66(6):594-602. doi: 10.1016/j.bjan.2016.08.002. Epub 2016 Sep 14.

BACKGROUND: Local anesthetics (LAs) are generally considered as safe, but cytotoxicity has been reported for several local anesthetics used in humans, which is not well investigated. In the present study, the cytotoxicity of lidocaine, ropivacaine and the combination of...

Anterior segment dysgenesis correlation with epithelial-mesenchymal transition in Smad4 knockout mice.

International journal of ophthalmology

Li J, Qin Y, Zhao FK, Wu D, He XF, Liu J, Zhao JY, Zhang JS.
PMID: 27500098
Int J Ophthalmol. 2016 Jul 18;9(7):943-7. doi: 10.18240/ijo.2016.07.02. eCollection 2016.

AIM: To explore the molecular mechanisms in lens development and the pathogenesis of Peters anomaly in Smad4 defective mice.METHODS: Le-Cre transgenic mouse line was employed to inactivate Smad4 in the surface ectoderm selectively. Pathological techniques were used to reveal...

An active Catharanthus roseus desacetoxyvindoline-4-hydroxylase-like gene and its transcriptional regulatory profile.

Botanical studies

Zhou C, Zhang J, Zhao SJ, Hu ZB.
PMID: 28510984
Bot Stud. 2014 Dec;55(1):29. doi: 10.1186/1999-3110-55-29. Epub 2014 Mar 13.

BACKGROUND: Desacetoxyvindoline-4-hydroxylase is a key enzyme in the biosynthesis of vindoline, the important intermediate leading to vinblastine and vincristine in Catharanthus roseus.RESULTS: A d4h-like gene has been isolated from C. roseus CCONCLUSION: These results suggest that d4h-like is closely...

[Improved color purity of green OLED device based on Au thin film].

Guang pu xue yu guang pu fen xi = Guang pu

Zhang YF, Zhao SL, Xu Z.
PMID: 25007596
Guang Pu Xue Yu Guang Pu Fen Xi. 2014 Apr;34(4):903-5.

Au was used as anode in some kind of organic electroluminescent devices. Sometimes transparent Au electrodes are required, which means that the thickness of Au electrode should be as thin as possible. Therefore, two metals together forming an electrode...

Thermal conductivity of the diamond-chain compound Cu₃(CO₃)₂(OH)₂.

Journal of physics. Condensed matter : an Institute of Physics journal

Wu JC, Song JD, Zhao ZY, Shi J, Xu HS, Zhao JY, Liu XG, Zhao X, Sun XF.
PMID: 26761589
J Phys Condens Matter. 2016 Feb 10;28(5):056002. doi: 10.1088/0953-8984/28/5/056002. Epub 2016 Jan 13.

Thermal conductivity (κ) of a distorted spin diamond-chain system, Cu3(CO3)2(OH)2, is studied at low temperatures down to 0.3 K and in magnetic fields up to 14 T. In zero field, the κ(T) curve with heat current along the chain...

The structure and function of NKAIN2-a candidate tumor suppressor.

International journal of clinical and experimental medicine

Zhao SC, Zhou BW, Luo F, Mao X, Lu YJ.
PMID: 26770299
Int J Clin Exp Med. 2015 Oct 15;8(10):17072-9. eCollection 2015.

The deletion of chromosomal region 6q was commonly found in several types of human cancers, although the tumor suppressor genes (TSGs) located within this genomic region are not well established. Our recent work detected recurrent chromosomal truncation at the...

Effects of Zusanli and Ashi Acupoint Electroacupuncture on Repair of Skeletal Muscle and Neuromuscular Junction in a Rabbit Gastrocnemius Contusion Model.

Evidence-based complementary and alternative medicine : eCAM

Yu ZG, Wang RG, Xiao C, Zhao JY, Shen Q, Liu SY, Xu QW, Zhang QX, Wang YT.
PMID: 27190536
Evid Based Complement Alternat Med. 2016;2016:7074563. doi: 10.1155/2016/7074563. Epub 2016 Apr 13.

Objective. To explore the effects of electroacupuncture (EA) at ST36 (EA-ST36) and at Ashi acupoints (EA-Ashi) on skeletal muscle repair. Methods. Seventy-five rabbits were randomly divided into five groups: normal, contusion, EA-Ashi, EA-ST36, and EA at Ashi acupoints and...

Verapamil suppresses cardiac alternans and ventricular arrhythmias in acute myocardial ischemia via ryanodine receptor inhibition.

American journal of translational research

Deng YL, Zhao JY, Yao JH, Tang Q, Zhang L, Zhou HL, Zhang CT, Lv JG, Quan XQ.
PMID: 28670363
Am J Transl Res. 2017 Jun 15;9(6):2712-2722. eCollection 2017.

T-wave alternans (TWA) is a potent arrhythmia substrate under the conditions of acute myocardial ischemia. Abnormal intracellular calcium cycling contributes to the genesis of cardiac alternans. Ryanodine receptor (RyR) is a pivotal Ca

The transcription factor Ikaros inhibits cell proliferation by downregulating ANXA4 expression in hepatocellular carcinoma.

American journal of cancer research

Liu YY, Ge C, Tian H, Jiang JY, Zhao FY, Li H, Chen TY, Yao M, Li JJ.
PMID: 28670491
Am J Cancer Res. 2017 Jun 01;7(6):1285-1297. eCollection 2017.

The occurrence and progression of hepatocellular carcinoma (HCC) are affected by complicated signal transduction factors. Our previous study identified Ikaros as a novel reactivated therapeutic target that acts as a transcriptional repressor and reactivates anticancer mechanisms in HCC therapy....

Discovery of novel inhibitors disrupting HIF-1.

PeerJ

Xue X, Zhao NY, Yu HT, Sun Y, Kang C, Huang QB, Sun HP, Wang XL, Li NG.
PMID: 27994971
PeerJ. 2016 Dec 15;4:e2757. doi: 10.7717/peerj.2757. eCollection 2016.

Major research efforts have been devoted to the discovery and development of new chemical entities that could inhibit the protein-protein interaction between HIF-1

Hindbrain Effects of L-Glutamate on Gastric Motility in Rats.

Gastroenterology research

Sun HZ, Zhao SZ, Cui XY, Ai HB.
PMID: 27956950
Gastroenterology Res. 2009 Feb;2(1):43-47. doi: 10.4021/gr2009.02.1274. Epub 2009 Jan 20.

BACKGROUND: There are no unanimous standpoints about the dorsal motor nucleus of the vagus (DMV) and nucleus of solitary tract (NTS) involving in the regulation of gastric motility up to now.METHODS: In this study, we injected L-Glutamate (L-Glu), an...

Showing 1 to 12 of 1981 entries