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Showing 1 to 12 of 466 entries
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Acitretin : A Review of its Pharmacology and Therapeutic Use.

Drugs

Pilkington T, Brogden RN.
PMID: 28421560
Drugs. 1992 Apr;43(4):597-627. doi: 10.2165/00003495-199243040-00010.

SYNOPSIS: Acitretin (etretin), a second generation monoaromatic retinoid for use in the treatment of severe psoriasis and other dermatoses, is the major active metabolite of etretinate and possesses a similar therapeutic index; i.e. a similar ratio of clinical efficacy...

Psychiatric conditions and general practitioner attendance prior to HPV vaccination and the risk of referral to a specialized hospital setting because of suspected adverse events following HPV vaccination: a register-based, matched case-control study.

Clinical epidemiology

Lützen TH, Bech BH, Mehlsen J, Høstrup Vestergaard C, Krogsgaard LW, Olsen J, Vestergaard M, Plana-Ripoll O, Rytter D.
PMID: 28979164
Clin Epidemiol. 2017 Sep 12;9:465-473. doi: 10.2147/CLEP.S135318. eCollection 2017.

AIM: No association between human papilloma virus (HPV) vaccination and numerous diseases has been found. Still, a large number of Danish women are reporting suspected adverse events. Other factors may play a role, and the aim of this study...

Tuning the size and magnetic properties of ZnxCo₁-xFe₂O₄ nanocrystallites.

Dalton transactions (Cambridge, England : 2003)

Schmidt M, Andersen HL, Granados-Miralles C, Saura-Múzquiz M, Stingaciu M, Christensen M.
PMID: 26947563
Dalton Trans. 2016 Apr 21;45(15):6439-48. doi: 10.1039/c5dt04701c.

Magnetically soft zinc-substituted cobalt ferrite ZnxCo1-xFe2O4 (x = 0.4, 0.5 and 0.6) nanocrystallites were successfully synthesized from cheap, abundant materials, using a mild, scalable hydrothermal route. The partial substitution of zinc by cobalt was generally observed to reduce the...

Tracking molecular resonance forms of donor-acceptor push-pull molecules by single-molecule conductance experiments.

Nature communications

Lissau H, Frisenda R, Olsen ST, Jevric M, Parker CR, Kadziola A, Hansen T, van der Zant HS, Brøndsted Nielsen M, Mikkelsen KV.
PMID: 26667583
Nat Commun. 2015 Dec 15;6:10233. doi: 10.1038/ncomms10233.

The ability of molecules to change colour on account of changes in solvent polarity is known as solvatochromism and used spectroscopically to characterize charge-transfer transitions in donor-acceptor molecules. Here we report that donor-acceptor-substituted molecular wires also exhibit distinct properties...

Microglia change from a reactive to an age-like phenotype with the time in culture.

Frontiers in cellular neuroscience

Caldeira C, Oliveira AF, Cunha C, Vaz AR, Falcão AS, Fernandes A, Brites D.
PMID: 24917789
Front Cell Neurosci. 2014 Jun 02;8:152. doi: 10.3389/fncel.2014.00152. eCollection 2014.

Age-related neurodegenerative diseases have been associated with chronic neuroinflammation and microglia activation. However, cumulative evidence supports that inflammation only occurs at an early stage once microglia change the endogenous characteristics with aging and switch to irresponsive/senescent and dystrophic phenotypes...

Transcriptomic landscape of lncRNAs in inflammatory bowel disease.

Genome medicine

Mirza AH, Berthelsen CH, Seemann SE, Pan X, Frederiksen KS, Vilien M, Gorodkin J, Pociot F.
PMID: 25991924
Genome Med. 2015 May 13;7(1):39. doi: 10.1186/s13073-015-0162-2. eCollection 2015.

BACKGROUND: Inflammatory bowel disease (IBD) is a complex multi-factorial inflammatory disease with Crohn's disease (CD) and ulcerative colitis (UC) being the two most common forms. A number of transcriptional profiling studies have provided compelling evidence that describe the role...

A microculture technique in the evaluation of lymphocyte transformation by mitogens and specific antigens in humans.

Irish journal of medical science

Woods RJ, Greally JF.
PMID: 27517258
Ir J Med Sci. 1976 Dec;145(1):369-77. doi: 10.1007/BF02938974.

A micro method forin vitro transformation of lymphocytes (Penhaleet al., 1974) by mitogens and antigens is presented. Using a range of concentrations, satisfactory responses were obtained with small numbers of lymphocytes in the presence of the mitogens, phytohaemagglutinin-P, Concanavalin-A,...

Integrated foam fractionation for heterologous rhamnolipid production with recombinant Pseudomonas putida in a bioreactor.

AMB Express

Beuker J, Steier A, Wittgens A, Rosenau F, Henkel M, Hausmann R.
PMID: 26860613
AMB Express. 2016 Mar;6(1):11. doi: 10.1186/s13568-016-0183-2. Epub 2016 Feb 09.

Heterologeous production of rhamnolipids in Pseudomonas putida is characterized by advantages of a non-pathogenic host and avoidance of the native quorum sensing regulation in Pseudomonas aeruginosa. Yet, downstream processing is a major problem in rhamnolipid production and increases in...

Risk of suicide, deliberate self-harm and psychiatric illness after the loss of a close relative: A nationwide cohort study.

World psychiatry : official journal of the World Psychiatric Association (WPA)

Guldin MB, Ina Siegismund Kjaersgaard M, Fenger-Grøn M, Thorlund Parner E, Li J, Prior A, Vestergaard M.
PMID: 28498584
World Psychiatry. 2017 Jun;16(2):193-199. doi: 10.1002/wps.20422.

The loss of a close relative is a common event, yet it is associated with increased risk of serious mental health conditions. No large-scale study has explored up to now the importance of the bereaved person's relation to the...

Is Thyroid Autoimmunity per se a Determinant of Quality of Life in Patients with Autoimmune Hypothyroidism?.

European thyroid journal

Watt T, Hegedüs L, Bjorner JB, Groenvold M, Bonnema SJ, Rasmussen AK, Feldt-Rasmussen U.
PMID: 24783018
Eur Thyroid J. 2012 Oct;1(3):186-92. doi: 10.1159/000342623. Epub 2012 Sep 29.

PURPOSE: To evaluate the relationship between thyroid variables and health-related quality of life (QoL) in patients with autoimmune hypothyroidism, using the thyroid-specific QoL questionnaire ThyPRO.METHODS: In a cross-sectional study, responses to the ThyPRO from 199 outpatients with autoimmune hypothyroidism...

Growth Promoting Activity of Chimeric Molecules of "Insulin-Insulin-like Growth Factor-I" .

Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica

Zhang X, Tang YH, Feng YM, Jing NH.
PMID: 12232638
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 1996;28(4):434-437.

The chimeric molecules of "Insulin-Insulin-like Growth Factor-I", Ins/IGFI(8) and Ins/IGF-I(11) were obtained by means of enzymatic semisynthesis. The growth promoting activity of these chimeric molecules were evaluated with a mouse mammary tumor derived cell line, GR2H6, and compared with...

Quantitative Neuropathology in Electrically Induced Generalized Convulsions.

Convulsive therapy

Dam AM, Dam M.
PMID: 11940850
Convuls Ther. 1986;2(2):77-89.

A critical review of the neuropathology associated with seizures is presented, with special reference to the damage to the brain claimed to result from electroconvulsive treatment (ECT). From the point of view of neuron loss, there is no evidence...

Showing 1 to 12 of 466 entries