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Showing 1 to 12 of 2949 entries
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Hybrid Monoterpenoid Indole Alkaloids Obtained as Artifacts from Rauvolfia tetraphylla.

Natural products and bioprospecting

Gao Y, Zhou DS, Hai P, Li Y, Wang F.
PMID: 26416155
Nat Prod Bioprospect. 2015 Oct;5(5):247-53. doi: 10.1007/s13659-015-0074-2. Epub 2015 Sep 29.

Five new hybrid monoterpenoid indole alkaloids bearing an unusual 2,2-dimethyl-4-oxopiperidin-6-yl moiety, namely rauvotetraphyllines F-H (1, 3, 4), 17-epi-rauvotetraphylline F (2) and 21-epi-rauvotetraphylline H (5), were isolated from the aerial parts of Rauvolfia tetraphylla. Their structures were established by extensive...

New Labdane diterpenes from Hedychium yunnanense with cytotoxicity and inhibitory effects on nitric oxide production.

Natural product research

Li YP, Zhao SM, Xu JJ, Zeng GZ, Li Y, Tan NH, Yang Y.
PMID: 26965832
Nat Prod Res. 2016 Dec;30(23):2669-2674. doi: 10.1080/14786419.2016.1143829. Epub 2016 Mar 11.

Two new labdane diterpenes, hedychenoids A (1) and B (2), were isolated from the rhizomes of Hedychium yunnanense, together with four known ones hedychenone (3), forrestin A (4), villosin (5) and calcaratarin C (6). Their structures were determined on...

Antioxidant and Cytotoxic Effect of Barringtonia racemosa and Hibiscus sabdariffa Fruit Extracts in MCF-7 Human Breast Cancer Cell Line.

Pharmacognosy research

Amran N, Rani AN, Mahmud R, Yin KB.
PMID: 26941539
Pharmacognosy Res. 2016 Jan-Mar;8(1):66-70. doi: 10.4103/0974-8490.171104.

BACKGROUND: The fruits of Barringtonia racemosa and Hibiscus sabdariffa have been used in the treatment of abscess, ulcer, cough, asthma, and diarrhea as traditional remedy.OBJECTIVE: This study aims to evaluate cytotoxic effect of B. racemosa and H. sabdariffa methanol...

The psychoactive drug 25B-NBOMe recapitulates rhabdomyolysis in zebrafish larvae.

Forensic toxicology

Kawahara G, Maeda H, Kikura-Hanajiri R, Yoshida KI, Hayashi YK.
PMID: 28890736
Forensic Toxicol. 2017;35(2):369-375. doi: 10.1007/s11419-017-0366-9. Epub 2017 Apr 18.

No abstract available.

Tilia tomentosa pectins exhibit dual mode of action on phagocytes as β-glucuronic acid monomers are abundant in their rhamnogalacturonans I.

Carbohydrate polymers

Georgiev YN, Paulsen BS, Kiyohara H, Ciz M, Ognyanov MH, Vasicek O, Rise F, Denev PN, Lojek A, Batsalova TG, Dzhambazov BM, Yamada H, Lund R, Barsett H, Krastanov AI, Yanakieva IZ, Kratchanova MG.
PMID: 28917854
Carbohydr Polym. 2017 Nov 01;175:178-191. doi: 10.1016/j.carbpol.2017.07.073. Epub 2017 Jul 25.

Silver linden flowers contain different pectins (PSI-PSIII) with immunomodulating properties. PSI is a low-esterified pectic polysaccharide with predominant homogalacturonan region, followed by rhamnogalacturonan I (RGI) with arabinogalactan II and RGII (traces) domains. PSII and PSIII are unusual glucuronidated RGI...

Palladium-Catalyzed Arylation of Carbasugars Enables the Discovery of Potent and Selective SGLT2 Inhibitors.

Angewandte Chemie (International ed. in English)

Ng WL, Lau KM, Lau CB, Shing TK.
PMID: 27699962
Angew Chem Int Ed Engl. 2016 Oct 24;55(44):13818-13821. doi: 10.1002/anie.201608758. Epub 2016 Oct 04.

Selective inhibition of the transporter protein sodium-glucose cotransporter 2 (SGLT2) has emerged as a promising way to control blood glucose level in diabetes patients. Reported herein is a short and convergent synthetic route towards some small-molecule SGLT2 inhibitors by...

Antimicrobial food packaging: potential and pitfalls.

Frontiers in microbiology

Malhotra B, Keshwani A, Kharkwal H.
PMID: 26136740
Front Microbiol. 2015 Jun 16;6:611. doi: 10.3389/fmicb.2015.00611. eCollection 2015.

Nowadays food preservation, quality maintenance, and safety are major growing concerns of the food industry. It is evident that over time consumers' demand for natural and safe food products with stringent regulations to prevent food-borne infectious diseases. Antimicrobial packaging...

Phenolic Derivatives of Artemisia Spicigera C. Koch Growing in Iran.

Iranian journal of pharmaceutical research : IJPR

Heshmati Afshar F, Delazar A, Nazemiyeh H, Khodaie L, Bamdad Moghaddam S.
PMID: 26664392
Iran J Pharm Res. 2015;14(4):1241-6.

This study aimed to determine phenolic compounds of Artemisia spicigera (family Asteraceae) growing in East-Azarbaijan province of Iran. 20%, 40 % and 60% SPE fractions of methanolic extract of A. spicigera, were subjected to reversed phase preparative HPLC, with...

Hierarchically Flower-like N-Doped Porous Carbon Materials Derived from an Explosive 3-Fold Interpenetrating Diamondoid Copper Metal-Organic Framework for a Supercapacitor.

Inorganic chemistry

Li ZX, Zou KY, Zhang X, Han T, Yang Y.
PMID: 27304095
Inorg Chem. 2016 Jul 05;55(13):6552-62. doi: 10.1021/acs.inorgchem.6b00746. Epub 2016 Jun 15.

A peculiar copper metal-organic framework (Cu-MOF) was synthesized by a self-assembly method, which presents a 3-fold interpenetrating diamondoid net based on the square-planar Cu(II) node. Although it exhibits a high degree of interpenetration, the Cu-MOF still exhibits a one-dimensional...

Traditional Uses, Phytochemistry, and Pharmacology of Olea europaea (Olive).

Evidence-based complementary and alternative medicine : eCAM

Hashmi MA, Khan A, Hanif M, Farooq U, Perveen S.
PMID: 25802541
Evid Based Complement Alternat Med. 2015;2015:541591. doi: 10.1155/2015/541591. Epub 2015 Feb 23.

Aim of the Review. To grasp the fragmented information available on the botany, traditional uses, phytochemistry, pharmacology, and toxicology of Olea europaea to explore its therapeutic potential and future research opportunities. Material and Methods. All the available information on...

Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice.

EXCLI journal

Bhat JU, Nizami Q, Asiaf A, Parray SA, Ahmad ST, Aslam M, Khanam R, Mujeeb M, Umar S, Siddiqi A.
PMID: 27298604
EXCLI J. 2012 Jan 20;11:1-6. eCollection 2012.

The aim of the present study was to evaluate the anticonvulsant effect of whole plant extracts of Melissa parviflora using MES and PTZ induced seizures models. The dried whole plant was subjected to extraction in methanol and water. The...

Toxicity Assessment of Wild Mushrooms from the Western Ghats, India: An .

Frontiers in pharmacology

Sai Latha S, Naveen S, Pradeep CK, Sivaraj C, Dinesh MG, Anilakumar KR.
PMID: 29487528
Front Pharmacol. 2018 Feb 13;9:90. doi: 10.3389/fphar.2018.00090. eCollection 2018.

No abstract available.

Showing 1 to 12 of 2949 entries