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Making mistakes in science: Eduard Pflüger, his scientific and professional concept of physiology, and his unsuccessful theory of diabetes (1903-1910).

Studies in history and philosophy of science

Schlich T.
PMID: 11623289
Stud Hist Philos Sci. 1993 Aug;24(3):411-41. doi: 10.1016/0039-3681(93)90036-j.

No abstract available.


Acta crystallographica. Section C, Crystal structure communications

Youngme S, Phatchimkun J, Chaichit N.
PMID: 17148888
Acta Crystallogr C. 2006 Dec;62:m574-6. doi: 10.1107/S0108270106039734. Epub 2006 Nov 10.

In a new hydrogen-bonded three-dimensional complex, [CuCl(NO3)(C10H8N2)(H2O)], the Cu atom has an elongated tetragonal octahedral environment, with two 2,2'-bipyridyl N atoms, one nitrate O atom and one Cl atom forming the equatorial plane, and a second O atom of...

Aqua(di-2-pyridylamine)oxalatocopper(II) monohydrate.

Acta crystallographica. Section C, Crystal structure communications

Youngme S, Phatchimkun J, Chaichit N.
PMID: 16763310
Acta Crystallogr C. 2006 Jun;62:m267-8. doi: 10.1107/S0108270106016398. Epub 2006 May 24.

In the structure of the title complex, [Cu(C2O4)(C10H9N3)(H2O)].H2O, the Cu(II) atom displays a square-pyramidal geometry, being coordinated by two N atoms from the di-2-pyridylamine ligand, two O atoms from the oxalate group and one O atom of a water...

Di-μ(4)-succinato-tetra-kis[aqua-phenanthrolinecopper(II)] tetra-nitrate tetra-hydrate.

Acta crystallographica. Section E, Structure reports online

Kitiphaisalnont P, Siripaisarnpipat S, Chaichit N.
PMID: 21578054
Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 03;65:m1284. doi: 10.1107/S1600536809039580.

In the title compound, [Cu(4)(C(4)H(4)O(4))(2)(C(12)H(8)N(2))(4)(H(2)O)(4)](NO(3))(4)·4H(2)O, the complete tetra-cation is generated by crystallographic inversion symmetry. Both unique Cu(2+) ions are coordinated by an N,N'-bidentate phenanthroline mol-ecule, two O-monodentate bis-bridging succinate dianions and a water mol-ecule, resulting in distorted CuN(2)O(3) square-based...

9-Meth-oxy-6a,11a-dimethyl-6a,11a-dihydro-6H-1-benzofuro[3,2-c]chromen-3-ol from Dalbergia oliveri.

Acta crystallographica. Section E, Structure reports online

Deesamer S, Chavasiri W, Chaichit N, Muangsin N, Kokpol U.
PMID: 21577851
Acta Crystallogr Sect E Struct Rep Online. 2009 Sep 09;65:o2387. doi: 10.1107/S1600536809034485.

The title compound, commonly known as (+)-(6aS,11aS)-medicarpin, C(16)H(14)O(4), was isolated from Dalbergia oliveri and displays a rigid mol-ecule consisting of four fused rings. The benzofuran system is inclined at an angle of 76.49 (2)° with respect to the chroman...

8-[(3,3-Dimethyl-oxiran-2-yl)methoxy-meth-yl]-11-hydr-oxy-2-isopropenyl-5-methyl-12-oxo-1,2,3,12-tetra-hydro-pyrano[3,2-a]xanthen-1-yl acetate.

Acta crystallographica. Section E, Structure reports online

Liangsakul J, Srisurichan S, Muangsin N, Chaichit N, Pornpakakul S.
PMID: 21577999
Acta Crystallogr Sect E Struct Rep Online. 2009 Sep 26;65:o2558-9. doi: 10.1107/S1600536809038343.

The title compound, commonly known as 14-methoxy-tajixanthone-25-acetate, C(28)H(30)O(8), was isolated from Emericella variecolor. The central xanthone core is approximately planar (r.m.s. deviation = 0.084 Å). The dihydro-pyran ring adopts a distorted half-chair conformation. The oxirane plane is oriented at...

Valve-sparing aortic root replacement in patients with Marfan syndrome-the Homburg experience.

Annals of cardiothoracic surgery

Schneider U, Ehrlich T, Karliova I, Giebels C, Schäfers HJ.
PMID: 29270383
Ann Cardiothorac Surg. 2017 Nov;6(6):697-703. doi: 10.21037/acs.2017.11.01.

No abstract available.

Ross Operation With Autologous External Autograft Stabilization-Long-term Results.

The Annals of thoracic surgery

Abeln KB, Schäfers S, Ehrlich T, Federspiel JM, Schäfers HJ.
PMID: 34678281
Ann Thorac Surg. 2021 Oct 20; doi: 10.1016/j.athoracsur.2021.09.017. Epub 2021 Oct 20.

BACKGROUND: We have proposed an external stabilization technique to minimize autograft dilatation after the Ross operation. This study analyzed autograft function and root dimensions after root replacement with and without external root support.METHODS: Between October 1995 and February 2021,...

Evaluation of Dexamethasone-Induced Osteoporosis In Vivo Using Zebrafish Scales.

Pharmaceuticals (Basel, Switzerland)

Chaichit S, Sato T, Yu H, Tanaka YK, Ogra Y, Mizoguchi T, Itoh M.
PMID: 34205111
Pharmaceuticals (Basel). 2021 Jun 03;14(6). doi: 10.3390/ph14060536.

Glucocorticoid-induced osteoporosis (GIOP) is a major cause of secondary osteoporosis, and the pathogenic mechanisms of GIOP remain to be elucidated. Here, we show a rapid dexamethasone-induced osteoporosis animal model using zebrafish scales. Intraperitoneal injection of dexamethasone over a 5-day...

Breakers and amplifiers in chromatin circuitry: acetylation and ubiquitination control the heterochromatin machinery.

Current opinion in structural biology

Bailey LT, Northall SJ, Schalch T.
PMID: 34303934
Curr Opin Struct Biol. 2021 Dec;71:156-163. doi: 10.1016/ Epub 2021 Jul 22.

Eukaryotic genomes are segregated into active euchromatic and repressed heterochromatic compartments. Gene regulatory networks, chromosomal structures, and genome integrity rely on the timely and locus-specific establishment of active and silent states to protect the genome and provide the basis...

The histone H3K9M mutation synergizes with H3K14 ubiquitylation to selectively sequester histone H3K9 methyltransferase Clr4 at heterochromatin.

Cell reports

Shan CM, Kim JK, Wang J, Bao K, Sun Y, Chen H, Yue JX, Stirpe A, Zhang Z, Lu C, Schalch T, Liti G, Nagy PL, Tong L, Qiao F, Jia S.
PMID: 34010645
Cell Rep. 2021 May 18;35(7):109137. doi: 10.1016/j.celrep.2021.109137.

Oncogenic histone lysine-to-methionine mutations block the methylation of their corresponding lysine residues on wild-type histones. One attractive model is that these mutations sequester histone methyltransferases, but genome-wide studies show that mutant histones and histone methyltransferases often do not colocalize....


Boonyanusith C, Saetang T, Wongkamheng K, Supiyanit Maiphae.
PMID: 30613173
Zookeys. 2018 Dec 20;(810):45-89. doi: 10.3897/zookeys.810.29253. eCollection 2018.

In this paper, two new species of

Showing 1 to 12 of 59 entries