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Showing 1 to 12 of 1047 entries
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Leveraging multilingual identities in computer science education

Broadening participation informal stem education

Jacob S, Warschauer M.
GSID: dXw34Mq5GmcJ
S Jacob, L Garcia, M Warschauer - … of second language learners and users, 2020 - Springer

Too often, educators assume that multilingual students come to school without the conceptual or linguistic resources necessary for learning the subjects of science, technology, engineering, and mathematics (STEM). To address this issue, K-12 STEM educational policymakers have called for...

Teacher perceptions of equity in high school computer science classrooms

Broadening Participation in Computing AND Program Evaluation

Cao Y, Jacob S, Richardson D, Zhou N.
GSID: LEHaj1f-Ay8J
N Zhou, Y Cao, S Jacob, D Richardson - … Transactions on Computing …, 2020 - dl.acm.org

Effective and equitable CS teaching is contingent on teachers' robust understanding of equity issues in CS classrooms. To this end, this study examined high school teachers' perceptions of equity during their participation in a CS teacher certificate program over...

Morphology-dependent performance of CuO anodes via facile and controllable synthesis for lithium-ion batteries.

ACS applied materials & interfaces

Wang C, Li Q, Wang F, Xia G, Liu R, Li D, Li N, Spendelow JS, Wu G.
PMID: 24377276
ACS Appl Mater Interfaces. 2014 Jan 22;6(2):1243-50. doi: 10.1021/am405061c. Epub 2014 Jan 07.

Nanostructured CuO anode materials with controllable morphologies have been successfully synthesized via a facile and environmentally friendly approach in the absence of any toxic surfactants or templates. In particular, leaf-like CuO, oatmeal-like CuO, and hollow-spherical CuO were obtained by...

Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis.

World journal of gastrointestinal pharmacology and therapeutics

Shailubhai K, Palejwala V, Arjunan KP, Saykhedkar S, Nefsky B, Foss JA, Comiskey S, Jacob GS, Plevy SE.
PMID: 26558155
World J Gastrointest Pharmacol Ther. 2015 Nov 06;6(4):213-22. doi: 10.4292/wjgpt.v6.i4.213.

AIM: To evaluate the effect of orally administered plecanatide or dolcanatide, analogs of uroguanylin, on amelioration of colitis in murine models.METHODS: The cyclic guanosine monophosphate (cGMP) stimulatory potency of plecanatide and dolcanatide was measured using a human colon carcinoma...

Development of a carbonate crust on alkaline nuclear waste sludge at the Hanford site.

Journal of hazardous materials

Page JS, Reynolds JG, Ely TM, Cooke GA.
PMID: 28850915
J Hazard Mater. 2018 Jan 15;342:375-382. doi: 10.1016/j.jhazmat.2017.08.033. Epub 2017 Aug 18.

Hard crusts on aging plutonium production waste have hindered the remediation of the Hanford Site in southeastern Washington, USA. In this study, samples were analyzed to determine the cause of a hard crust that developed on the highly radioactive...

Contemporaneous Dual Catalysis: Aldol Products from Non-Carbonyl Substrates.

Chemistry (Weinheim an der Bergstrasse, Germany)

Trost BM, Tracy JS.
PMID: 26334442
Chemistry. 2015 Oct 19;21(43):15108-12. doi: 10.1002/chem.201502973. Epub 2015 Sep 03.

The aldol reaction represents an important class of atom-economic carbon-carbon bond-forming reactions vital to modern organic synthesis. Despite the attention this reaction has received, issues related to chemo- and regioselectivity as well as reactivity of readily enolizable electrophiles remain....

β-catenin and PI3Kδ inhibition expands precursor Th17 cells with heightened stemness and antitumor activity.

JCI insight

Majchrzak K, Nelson MH, Bowers JS, Bailey SR, Wyatt MM, Wrangle JM, Rubinstein MP, Varela JC, Li Z, Himes RA, Chan SS, Paulos CM.
PMID: 28422756
JCI Insight. 2017 Apr 20;2(8). doi: 10.1172/jci.insight.90547. eCollection 2017 Apr 20.

ICOS costimulation generates Th17 cells with durable memory responses to tumor. Herein, we found that ICOS induces PI3K/p110δ/Akt and Wnt/β-catenin pathways in Th17 cells. Coinhibiting PI3Kδ and β-catenin altered the biological fate of Th17 cells. Th17 cells inhibited of...

Strong Reduction of Thermal Conductivity and Enhanced Thermoelectric Properties in CoSbS.

Scientific reports

Chmielowski R, Bhattacharya S, Jacob S, Péré D, Jacob A, Moriya K, Delatouche B, Roussel P, Madsen G, Dennler G.
PMID: 28425457
Sci Rep. 2017 Apr 20;7:46630. doi: 10.1038/srep46630.

In order to reduce the thermal conductivity of CoSbS, a newly developed thermoelectric semiconductor, we have aimed at intentionally induce atomic disorder in its structure. This endeavor was guided by Density Functional Theory(DFT) calculations which indicated that substituting sulfur...

Correction to Structure-Activity Relationship, Drug Metabolism and Pharmacokinetics Properties Optimization, and in Vivo Studies of New Brain Penetrant Triple T-Type Calcium Channel Blockers.

Journal of medicinal chemistry

Siegrist R, Pozzi D, Jacob G, Torrisi C, Colas K, Braibant B, Mawet J, Pfeifer T, de Kanter R, Roch C, Kessler M, Moon R, Corminboeuf O, Bezençon O.
PMID: 28234473
J Med Chem. 2017 Mar 09;60(5):2163. doi: 10.1021/acs.jmedchem.7b00219. Epub 2017 Feb 24.

No abstract available.

The Effect of Ivabradine on the Heart Rate and Sympathovagal Balance in Postural Tachycardia Syndrome Patients.

Rambam Maimonides medical journal

Barzilai M, Jacob G.
PMID: 26241226
Rambam Maimonides Med J. 2015 Jul 30;6(3). doi: 10.5041/RMMJ.10213.

BACKGROUND: Postural tachycardia syndrome (POTS) is a common form of chronic orthostatic intolerance. The remarkable increase in heart rate (HR) upon standing is the hallmark of this syndrome. Treatment of POTS patients is challenging and includes drugs that slow...

Residual stresses in colloidal gels.

Soft matter

Moghimi E, Jacob AR, Petekidis G.
PMID: 29028062
Soft Matter. 2017 Nov 08;13(43):7824-7833. doi: 10.1039/c7sm01655g.

A combination of experiments and Brownian Dynamics (BD) simulations is utilized to examine internal stresses in colloidal gels brought to rest from steady shear at different shear rates. A model colloidal gel with intermediate volume fraction is chosen where...

Modelling the acid/base .

Metabolomics : Official journal of the Metabolomic Society

Tredwell GD, Bundy JG, De Iorio M, Ebbels TM.
PMID: 27729829
Metabolomics. 2016;12(10):152. doi: 10.1007/s11306-016-1101-y. Epub 2016 Sep 15.

INTRODUCTION: Despite the use of buffering agents the OBJECTIVES: To investigate the acid, base and metal ion dependent METHODS: Urine samples from five different individuals were collected and pooled, and pre-treated with Chelex-100 ion exchange resin. Urine samples were...

Showing 1 to 12 of 1047 entries