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Showing 1 to 12 of 1197 entries
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Metallothionein, Copper and Alpha-Synuclein in Alpha-Synucleinopathies.

Frontiers in neuroscience

Okita Y, Rcom-H'cheo-Gauthier AN, Goulding M, Chung RS, Faller P, Pountney DL.
PMID: 28420950
Front Neurosci. 2017 Apr 04;11:114. doi: 10.3389/fnins.2017.00114. eCollection 2017.

Metallothioneins (MTs) are proteins that function by metal exchange to regulate the bioavailability of metals, such as zinc and copper. Copper functions in the brain to regulate mitochondria, neurotransmitter production, and cell signaling. Inappropriate copper binding can result in...

Efficacy of temozolomide and bevacizumab for the treatment of leptomeningeal dissemination of recurrent glioblastoma: A case report.

Oncology letters

Okita Y, Nonaka M, Umehara T, Kanemura Y, Kodama Y, Mano M, Nakajima S.
PMID: 25789061
Oncol Lett. 2015 Apr;9(4):1885-1888. doi: 10.3892/ol.2015.2940. Epub 2015 Feb 06.

The prognosis of leptomeningeal dissemination of recurrent glioblastoma is poor, and chemotherapy results in minimal palliative efficacy. Temozolomide (TMZ) is an established therapy for patients with malignant glioma and the standard of care in parenchymal gliomas; however, few reports...

Assessment of the features of serum apolipoprotein profiles in chronic HCV infection: difference between HCV genotypes 1b and 2.

Hepatology international

Seki N, Sugita T, Aida Y, Itagaki M, Ishiguro H, Sutoh S, Abe H, Tsubota A, Matsushima M, Aizawa Y.
PMID: 26202760
Hepatol Int. 2014 Oct;8(4):550-9. doi: 10.1007/s12072-014-9572-2. Epub 2014 Sep 26.

BACKGROUND: The life cycle of hepatitis C virus (HCV) is tightly associated with host lipoprotein metabolic pathways. Apolipoprotein is present on the outer surface of lipoprotein particles and plays an important role in lipoprotein metabolism. We aimed to elucidate...

Selective Oxidation of 2-Methylnaphthalene to 2-Methyl-l-naphthol by Rhodococcus sp. M192.

Bioscience, biotechnology, and biochemistry

Taguchi H, Kita S, Kobayashi M, Tan Y.
PMID: 27281139
Biosci Biotechnol Biochem. 1996 Jan;60(5):769-72. doi: 10.1271/bbb.60.769.

About 6000 isolates of microorganisms assimilating methylketones (C3-C6) were tested for their selective oxidation of 2-methylnaphthalene to 2-methyl-1-naphthol. Strain M192 was the highest 2-methyl-1-naphthol producer and was classified as the genus Rhodococcus. The optimal conditions for the site-specific oxidation...

Independent risk factors for a complicated hospital course in intensive care unit overdose patients.

Acute medicine & surgery

Tarui T, Yoshikawa K, Miyakuni Y, Kaita Y, Tamada N, Matsuda T, Miyauchi H, Yamada K, Matsuda T, Yamaguchi Y.
PMID: 29123701
Acute Med Surg. 2014 Sep 17;2(2):98-104. doi: 10.1002/ams2.77. eCollection 2015 Apr.

AIM: The purpose of the present study was to identify risk factors associated with a complicated hospital course in overdose patients admitted to the intensive care unit.METHODS: A total of 335 overdose patients were retrospectively studied in the surgical...

Stabilized pyrrolyl iodonium salts and metal-free oxidative cross-coupling.

Organic & biomolecular chemistry

Morimoto K, Ohnishi Y, Koseki D, Nakamura A, Dohi T, Kita Y.
PMID: 27722732
Org Biomol Chem. 2016 Sep 26;14(38):8947-8951. doi: 10.1039/c6ob01764a.

Pyrrole-aryl derivatives are important due to their unique biological activities in medicinal chemistry. We now report a new oxidative biaryl coupling for pyrroles and indoles toward various arenes using a hypervalent iodine reagent and an appropriate stabilizer for pyrrolyl...

A wild Indo-Pacific bottlenose dolphin adopts a socially and genetically distant neonate.

Scientific reports

Sakai M, Kita YF, Kogi K, Shinohara M, Morisaka T, Shiina T, Inoue-Murayama M.
PMID: 27049937
Sci Rep. 2016 Apr 06;6:23902. doi: 10.1038/srep23902.

Alloparental behaviour and adoption have been reported in many mammals and birds. Such behaviours are energetically costly, and their causes and functions remain unclear. We observed the adoption behaviour of a wild Indo-Pacific bottlenose dolphin (Tursiops aduncus) near Mikura...

Spontaneous ligand nitrosation and self-assembly into a pentacopper metallacrown complex.

Dalton transactions (Cambridge, England : 2003)

Otsuki J, Sekine T, Kida Y, Shinozaki Y, Kobayashi S, Tamura T, Sugawa K, Yoshikawa I, Houjou H, Yoshikawa H, Tsukamoto A.
PMID: 28181609
Dalton Trans. 2017 Feb 28;46(9):2760-2764. doi: 10.1039/c6dt04696g.

Upon mixing acetylacetonedioxime and copper(ii) nitrate in water, the acetylacetonedioxime is spontaneously nitrosated at the central α-carbon and four of the nitrosated ligand molecules and five Cu ions self-assemble into a pentanuclear metallacrown complex, whose structure has been revealed...

A case of primary metastatic glassy cell carcinoma of the uterine cervix that responded to combined docetaxel and carboplatin.

Gynecologic oncology case reports

Ukita Y, Tsubamoto H, Kato T, Suno S, Shibahara H.
PMID: 24371710
Gynecol Oncol Case Rep. 2013 Jul 22;6:19-21. doi: 10.1016/j.gynor.2013.07.004. eCollection 2013.

•Glassy cell carcinoma (GCC) of the cervix is rare and aggressive.•A few case reports have described a response to intravenous chemotherapy for this malignancy.•This is the first report of a GCC case that responded to a combination of docetaxel...

Bronchiolitis and bacteraemia caused by Burkholderia gladioli in a non-lung transplantation patient.

New microbes and new infections

Imataki O, Kita N, Nakayama-Imaohji H, Kida JI, Kuwahara T, Uemura M.
PMID: 25566397
New Microbes New Infect. 2014 Nov;2(6):175-6. doi: 10.1002/nmi2.64. Epub 2014 Sep 25.

No abstract available.

Generation of intense subcycle optical pulses in a gas.

Optics express

Kida Y, Imasaka T.
PMID: 25969322
Opt Express. 2015 May 04;23(9):12373-81. doi: 10.1364/OE.23.012373.

The generation of intense subcycle laser pulses during the propagation of two-color femtosecond pulses in a gas medium is investigated theoretically and experimentally. Four-wave mixing induced by the laser pulses in a gas medium generates multi-octave laser radiation from...

Phthalimide Compounds Containing a Trifluoromethylphenyl Group and Electron-Donating Aryl Groups: Color-Tuning and Enhancement of Triboluminescence.

The Journal of organic chemistry

Nishida J, Ohura H, Kita Y, Hasegawa H, Kawase T, Takada N, Sato H, Sei Y, Yamashita Y.
PMID: 26652502
J Org Chem. 2016 Jan 15;81(2):433-41. doi: 10.1021/acs.joc.5b02191. Epub 2015 Dec 24.

Trifluoromethylphenyl-substituted phthalimide derivatives favorably form triboluminescence (TL) active noncentrosymmetric crystals. Oligothienyl-, oligophenyl-, and naphthyl-substituted phthalimide derivatives were successfully developed as a series of metal free TL compounds. X-ray crystal structure analyses of bithienyl and naphthyl derivatives revealed noncentrosymmetric layer...

Showing 1 to 12 of 1197 entries