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Showing 1 to 12 of 86 entries
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The Use of Atomic Force Microscopy for 3D Analysis of Nucleic Acid Hybridization on Microarrays.

Acta naturae

Dubrovin EV, Presnova GV, Rubtsova MY, Egorov AM, Grigorenko VG, Yaminsky IV.
PMID: 26085952
Acta Naturae. 2015 Apr-Jun;7(2):108-14.

Oligonucleotide microarrays are considered today to be one of the most efficient methods of gene diagnostics. The capability of atomic force microscopy (AFM) to characterize the three-dimensional morphology of single molecules on a surface allows one to use it...

The Vole Gene Map.

ILAR journal

Nesterova TB, Mazurok NA, Rubtsova NV, Isaenko AA, Zakian SM.
PMID: 11528071
ILAR J. 1998;39(2):138-144. doi: 10.1093/ilar.39.2-3.138.

No abstract available.

[New drugs at the services of public health].

Meditsinskaia promyshlennost' SSSR

RUBTSOV MV, MASHKOVSKII MD.
PMID: 13012781
Med Prom SSSR. 1952 Nov-Dec;6(6):23-6.

No abstract available.

Surgical Approach to Treatment of Necrotizing Pancreatitis: Early Primary Drainage without Necrosectomy. Review of Seven Recent Cases.

Case reports in gastroenterology

Rubtsov MA, Galeev SI.
PMID: 20651973
Case Rep Gastroenterol. 2009 Apr 17;3(1):97-104. doi: 10.1159/000212991.

Unsatisfactory results of surgery in the late course of pancreatic necrosis made us search for indications and variants of operation in the early phase of the disease. As early surgical intervention, the universal approach was used in 7 patients...

The role of HCV e2 protein glycosylation in functioning of virus envelope proteins in insect and Mammalian cells.

Acta naturae

Orlova OV, Drutsa VL, Spirin PV, Prasolov VS, Rubtsov PM, Kochetkov SN, Beljelarskaya SN.
PMID: 25927005
Acta Naturae. 2015 Jan-Mar;7(1):87-97.

The hepatitis C virus (HCV) envelope proteins E1 and E2, being virion components, are involved in the formation of infectious particles in infected cells. The detailed structure of the infectious particle of HCV remains poorly understood. Moreover, the virion...

[Criterial parameter of hygienic regulation for exposure to rarely repeated ultrashort electromagnetic impulses].

Meditsina truda i promyshlennaia ekologiia

Gavrish NN, Ushakov IB, Pokhodzeĭ LV, Rubtsova NB, Pal'tsev IuP.
PMID: 20151598
Med Tr Prom Ekol. 2009;(12):27-32.

The authors justified an estimated induced current density as a criterial parameter for hygienic regulation of exposure to rarely repeated ultrashort electromagnetic impulses of nanosecond duration in electrical discharge devices applied in scientific research. The authors defined a threshold...

CRISPR/Cas9 nickase mediated targeting of urokinase receptor gene inhibits neuroblastoma cell proliferation.

Oncotarget

Rysenkova KD, Semina EV, Karagyaur MN, Shmakova AA, Dyikanov DT, Vasiluev PA, Rubtsov YP, Rubina KA, Tkachuk VA.
PMID: 30034627
Oncotarget. 2018 Jun 29;9(50):29414-29430. doi: 10.18632/oncotarget.25647. eCollection 2018 Jun 29.

Neuroblastoma is a tumor arising from pluripotent sympathoadrenal precursor cells of neural cell origin. Neuroblastoma is one of the most aggressive childhood tumors with highly invasive and metastatic potential. The increased expression of urokinase and its receptor is often...

A One-Step PCR-Based Assay to Evaluate the Efficiency and Precision of Genomic DNA-Editing Tools.

Molecular therapy. Methods & clinical development

Germini D, Bou Saada Y, Tsfasman T, Osina K, Robin C, Lomov N, Rubtsov M, Sjakste N, Lipinski M, Vassetzky Y.
PMID: 28480303
Mol Ther Methods Clin Dev. 2017 Mar 08;5:43-50. doi: 10.1016/j.omtm.2017.03.001. eCollection 2017 Jun 16.

Despite rapid progress, many problems and limitations persist and limit the applicability of gene-editing techniques. Making use of meganucleases, TALENs, or CRISPR/Cas9-based tools requires an initial step of pre-screening to determine the efficiency and specificity of the designed tools....

[Glucokinase and glucokinase regulatory proteins as molecular targets for novel antidiabetic drugs].

Molekuliarnaia biologiia

Rubtsov PM, Igudin EL, Tiulpakov AN.
PMID: 26299854
Mol Biol (Mosk). 2015 Jul-Aug;49(4):555-60. doi: 10.7868/S002689841504014X.

The impairment of glucose homeostasis leads to hyperglycemia and type-2 diabetes mellitus. Glucokinase (GK), an enzyme that catalyzes the conversion of glucose to glucose-6-phosphate in pancreatic ß-cells, liver hepatocytes, specific hypothalamic neurons, and intestine enterocytes, is a key regulator...

Adipocyte Biology from the Perspective of In Vivo Research: Review of Key Transcription Factors.

International journal of molecular sciences

Evseeva MN, Balashova MS, Kulebyakin KY, Rubtsov YP.
PMID: 35008748
Int J Mol Sci. 2021 Dec 28;23(1). doi: 10.3390/ijms23010322.

Obesity and type 2 diabetes are both significant contributors to the contemporary pandemic of non-communicable diseases. Both disorders are interconnected and associated with the disruption of normal homeostasis in adipose tissue. Consequently, exploring adipose tissue differentiation and homeostasis is...

PARP1 Regulates the Biogenesis and Activity of Telomerase Complex Through Modification of H/ACA-Proteins.

Frontiers in cell and developmental biology

Savelyev NV, Shepelev NM, Lavrik OI, Rubtsova MP, Dontsova OA.
PMID: 34095104
Front Cell Dev Biol. 2021 May 19;9:621134. doi: 10.3389/fcell.2021.621134. eCollection 2021.

Poly(ADP-ribose) polymerase 1 (PARP1) is established as a key regulator of the cellular DNA damage response and apoptosis. In addition, PARP1 participates in the global regulation of DNA repair, transcription, telomere maintenance, and inflammation response by modulating various DNA-protein...

The shifting age distribution of people with HIV using antiretroviral therapy in the United States, 2020 to 2030.

AIDS (London, England)

Althoff KN, Stewart CN, Humes E, Zhang J, Gerace L, Boyd CM, Wong C, Justice AC, Gebo K, Thorne JE, Rubtsova AA, Horberg MA, Silverberg MJ, Leng SX, Rebeiro PF, Moore RD, Buchacz K, Kasaie P.
PMID: 34750289
AIDS. 2021 Nov 08; doi: 10.1097/QAD.0000000000003128. Epub 2021 Nov 08.

OBJECTIVE: To project the future age distribution of people with HIV using antiretroviral therapy (ART) in the US, under expected trends in HIV diagnosis and survival (baseline scenario) and achieving the Ending the HIV Epidemic (EHE) goals of a...

Showing 1 to 12 of 86 entries