Journal of obesity
Bjørndal B, Burri L, Staalesen V, Skorve J, Berge RK.
J Obes. 2011;2011:490650. doi: 10.1155/2011/490650. Epub 2011 Feb 15.
Adipose tissue metabolism is closely linked to insulin resistance, and differential fat distributions are associated with disorders like hypertension, diabetes, and cardiovascular disease. Adipose tissues vary in their impact on metabolic risk due to diverse gene expression profiles, leading...
Patient preference and adherence
Bauer AM, Parker MM, Moffet HH, Schillinger D, Adler NE, Adams AS, Schmittdiel JA, Katon WJ, Karter AJ.
Patient Prefer Adherence. 2017 Mar 24;11:643-652. doi: 10.2147/PPA.S124181. eCollection 2017.
OBJECTIVE: Among adults with diabetes, depression is associated with poorer adherence to cardiometabolic medications in ongoing users; however, it is unknown whether this extends to early adherence among patients newly prescribed these medications. This study examined whether depressive symptoms...
Journal of lipid and atherosclerosis
Park SJ, Park DH.
J Lipid Atheroscler. 2020 Sep;9(3):406-418. doi: 10.12997/jla.2020.9.3.406. Epub 2020 Sep 18.
Dyslipidemia refers to an abnormal amount of lipid in the blood, and the total cholesterol level is defined as the sum of high-density lipoprotein cholesterol, low-density lipoprotein (LDL) cholesterol, and very-LDL cholesterol concentrations. In Korea, the westernization of lifestyle...
The Canadian journal of hospital pharmacy
Dillon C, Peddle J, Twells L, Lester K, Midodzi W, Manning K, Murphy R, Pace D, Smith C, Boone D, Gregory D.
Can J Hosp Pharm. 2015 Mar-Apr;68(2):113-20. doi: 10.4212/cjhp.v68i2.1436.
BACKGROUND: Patients who have undergone bariatric surgery generally need fewer medications as they experience improvement in, or even resolution of, various medical conditions, including type 2 diabetes mellitus, hypertension, and dyslipidemia. Published data on changes in medication use after...
Pharmacy (Basel, Switzerland)
Hodgkins AJ, Mullan J, Mayne D, Bonney A.
Pharmacy (Basel). 2019 Sep 18;7(3). doi: 10.3390/pharmacy7030134.
General practice electronic health record (EHR) data have significant potential for clinical research. This study demonstrates the feasibility of utilising longitudinal EHR data analysis to address clinically relevant outcomes and uses the relationship between lipid medication prescription and all-cause...
Chapman JM, Wyrick SD, Maguire JH, Cocolas GH, Hall IH.
Pharm Res. 1984 Nov;1(6):267-9. doi: 10.1023/A:1016346018962.
A number of substituted phthalimide, 1, 8-naphthalimide, succinimide and glutarimide derivatives demonstrated significant hypolipidemic activity at 20 mg/kg/ day, I.P. after 16 days dosing. The N-(n-pentyl) succinimide proved to be the most potent analogue of the new compounds, lowering...
Pakistan journal of pharmaceutical sciences
Saify ZS, Hassan S, Arif M, Ahmad F, Chishti KA, Siddiqui S.
Pak J Pharm Sci. 2000 Jan;13(1):1-11.
The fish oil and its constituents have been studied in detail with special reference to ailments. The discovery of omega-3 fatty acids led to a detailed investigation about its effect and role as anti-cholesterolemic agents. The effect of fish...
JMIR research protocols
Mozetic V, Freitas CG, Riera R.
JMIR Res Protoc. 2017 Feb 22;6(2):e30. doi: 10.2196/resprot.6650.
BACKGROUND: Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus, and more than 75% of patients who have had diabetes for more than 20 years will have some degree of DR. This disease is highly destructive to...
Acta medica portuguesa
Ferreira R, Ferreira D, Correia MJ, De Sá ME, De Sousa JV, Sousa JV, Tavares MG.
Acta Med Port. 2001 Mar-Apr;14(2):149-69.
Myocardial infarction is still one of the main causes of mortality and morbidity in Western countries. The advances made in the last 30 years have made it possible to reduce mortality significantly (which is currently below two digits) as...
Clinical pharmacology : advances and applications
Di Pierro F, Putignano P, Villanova N, Montesi L, Moscatiello S, Marchesini G.
Clin Pharmacol. 2013 Nov 19;5:167-74. doi: 10.2147/CPAA.S54308. eCollection 2013.
BACKGROUND: Berberine is an isoquinoline alkaloid widely used to improve the glucidic and lipidic profiles of patients with hypercholesterolemia, metabolic syndrome, and type 2 diabetes. The limitation of berberine seems to be its poor oral bioavailability, which is affected...
Coronary artery disease
Krysiak R, Kowalcze K, Okopień B.
Coron Artery Dis. 2021 Dec 01;32(8):706-712. doi: 10.1097/MCA.0000000000001031.
BACKGROUND: Hypothyroidism, hyperprolactinemia, macroprolactinemia and low vitamin D status were found to impair pleiotropic effects of hypolipidemic agents. The aim of the current study was to investigate whether cardiometabolic effects of atorvastatin in men are determined by endogenous testosterone.METHODS:...
Hall IH, Chapman JM, Gilbert C.
Pharm Res. 1984 Mar;1(2):63-8. doi: 10.1023/A:1016399213993.
A series of benzenetricarboxylic acids was shown to be potent hypolipidemic agents in rodents. Terephthalic acid proved to be one of the more potent agents, lowering serum cholesterol 42% and serum triglyceride 33 % at 20 mg/kg/day for 16...