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Higher discontinuation and lower survival rates are likely in elderly Japanese patients with advanced hepatocellular carcinoma receiving sorafenib.

Hepatology research : the official journal of the Japan Society of Hepatology

Morimoto M, Numata K, Kondo M, Hidaka H, Takada J, Shibuya A, Kobayashi S, Ohkawa S, Okuse C, Morita S, Taguri M, Tanaka K.
PMID: 21348907
Hepatol Res. 2011 Apr;41(4):296-302. doi: 10.1111/j.1872-034X.2011.00778.x. Epub 2011 Feb 23.

AIM:   Sorafenib is approved for the treatment of advanced hepatocellular carcinoma (HCC) in Japan; however, its tolerability and efficacy in elderly patients with HCC have not been clarified. We aimed to evaluate the tolerability and efficacy of sorafenib with...

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Morimoto M, Numata K, Kondo M, et al. Higher discontinuation and lower survival rates are likely in elderly Japanese patients with advanced hepatocellular carcinoma receiving sorafenib. Hepatol Res. 2011;41(4):296-302doi: 10.1111/j.1872-034X.2011.00778.x.
Morimoto, M., Numata, K., Kondo, M., Hidaka, H., Takada, J., Shibuya, A., Kobayashi, S., Ohkawa, S., Okuse, C., Morita, S., Taguri, M., & Tanaka, K. (2011). Higher discontinuation and lower survival rates are likely in elderly Japanese patients with advanced hepatocellular carcinoma receiving sorafenib. Hepatology research : the official journal of the Japan Society of Hepatology, 41(4), 296-302. https://doi.org/10.1111/j.1872-034X.2011.00778.x
Morimoto, Manabu, et al. "Higher discontinuation and lower survival rates are likely in elderly Japanese patients with advanced hepatocellular carcinoma receiving sorafenib." Hepatology research : the official journal of the Japan Society of Hepatology vol. 41,4 (2011): 296-302. doi: https://doi.org/10.1111/j.1872-034X.2011.00778.x
Morimoto M, Numata K, Kondo M, Hidaka H, Takada J, Shibuya A, Kobayashi S, Ohkawa S, Okuse C, Morita S, Taguri M, Tanaka K. Higher discontinuation and lower survival rates are likely in elderly Japanese patients with advanced hepatocellular carcinoma receiving sorafenib. Hepatol Res. 2011 Apr;41(4):296-302. doi: 10.1111/j.1872-034X.2011.00778.x. Epub 2011 Feb 23. PMID: 21348907.
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Age-related differences in fibrinolytic parameters in patients with acute traumatic brain injury.

Surgical neurology international

Nakae R, Yokobori S, Takayama Y, Kuwamoto K, Naoe Y, Yokota H.
PMID: 28966820
Surg Neurol Int. 2017 Sep 06;8:214. doi: 10.4103/sni.sni_56_17. eCollection 2017.

BACKGROUND: Coagulopathy and old age have been associated with poor outcomes in traumatic brain injury (TBI) patients; however, the relationships of coagulopathy and age with the acute phase of TBI remain unclear. We hypothesized that coagulation/fibrinolytic abnormalities are more...

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Nakae R, Yokobori S, Takayama Y, et al. Age-related differences in fibrinolytic parameters in patients with acute traumatic brain injury. Surg Neurol Int. 2017;8:214doi: 10.4103/sni.sni_56_17.
Nakae, R., Yokobori, S., Takayama, Y., Kuwamoto, K., Naoe, Y., & Yokota, H. (2017). Age-related differences in fibrinolytic parameters in patients with acute traumatic brain injury. Surgical neurology international, 8214. https://doi.org/10.4103/sni.sni_56_17
Nakae, Ryuta, et al. "Age-related differences in fibrinolytic parameters in patients with acute traumatic brain injury." Surgical neurology international vol. 8 (2017): 214. doi: https://doi.org/10.4103/sni.sni_56_17
Nakae R, Yokobori S, Takayama Y, Kuwamoto K, Naoe Y, Yokota H. Age-related differences in fibrinolytic parameters in patients with acute traumatic brain injury. Surg Neurol Int. 2017 Sep 06;8:214. doi: 10.4103/sni.sni_56_17. eCollection 2017. PMID: 28966820; PMCID: PMC5609444.
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Screening for hemostatic activities of popular Chinese medicinal herbs in vitro.

Journal of intercultural ethnopharmacology

Ohkura N, Yokouchi H, Mimura M, Nakamura R, Atsumi G.
PMID: 26401379
J Intercult Ethnopharmacol. 2015 Jan-Mar;4(1):19-23. doi: 10.5455/jice.20141128032845. Epub 2015 Jan 03.

AIMS: This study aimed to identify new hemostyptics by assessing the coagulation enhancing activity of 114 Chinese herbal extracts in vitro.METHODS: Herbs were boiled in water for 30 min, filtered and then lyophilized filtrates (10 mg/mL) were dissolved in...

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Ohkura N, Yokouchi H, Mimura M, et al. Screening for hemostatic activities of popular Chinese medicinal herbs in vitro. J Intercult Ethnopharmacol. 2015;4(1):19-23doi: 10.5455/jice.20141128032845.
Ohkura, N., Yokouchi, H., Mimura, M., Nakamura, R., & Atsumi, G. (2015). Screening for hemostatic activities of popular Chinese medicinal herbs in vitro. Journal of intercultural ethnopharmacology, 4(1), 19-23. https://doi.org/10.5455/jice.20141128032845
Ohkura, Naoki, et al. "Screening for hemostatic activities of popular Chinese medicinal herbs in vitro." Journal of intercultural ethnopharmacology vol. 4,1 (2015): 19-23. doi: https://doi.org/10.5455/jice.20141128032845
Ohkura N, Yokouchi H, Mimura M, Nakamura R, Atsumi G. Screening for hemostatic activities of popular Chinese medicinal herbs in vitro. J Intercult Ethnopharmacol. 2015 Jan-Mar;4(1):19-23. doi: 10.5455/jice.20141128032845. Epub 2015 Jan 03. PMID: 26401379; PMCID: PMC4566763.
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Influencing factors of transient elastography in detecting liver stiffness.

Experimental and therapeutic medicine

Shan R, Yin H, Yang W, Li J, Zhang M, Zhao M, Shao J, Wang A.
PMID: 27698728
Exp Ther Med. 2016 Oct;12(4):2302-2306. doi: 10.3892/etm.2016.3617. Epub 2016 Aug 24.

Liver stiffness, which correlates well with liver fibrosis stage, can be measured noninvasively by transient elastography, also known as Fibroscan. The present study aimed to determine the independent factors influencing Fibroscan detection by multiple regression analysis. A total of...

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Shan R, Yin H, Yang W, et al. Influencing factors of transient elastography in detecting liver stiffness. Exp Ther Med. 2016;12(4):2302-2306doi: 10.3892/etm.2016.3617.
Shan, R., Yin, H., Yang, W., Li, J., Zhang, M., Zhao, M., Shao, J., & Wang, A. (2016). Influencing factors of transient elastography in detecting liver stiffness. Experimental and therapeutic medicine, 12(4), 2302-2306. https://doi.org/10.3892/etm.2016.3617
Shan, Rong, et al. "Influencing factors of transient elastography in detecting liver stiffness." Experimental and therapeutic medicine vol. 12,4 (2016): 2302-2306. doi: https://doi.org/10.3892/etm.2016.3617
Shan R, Yin H, Yang W, Li J, Zhang M, Zhao M, Shao J, Wang A. Influencing factors of transient elastography in detecting liver stiffness. Exp Ther Med. 2016 Oct;12(4):2302-2306. doi: 10.3892/etm.2016.3617. Epub 2016 Aug 24. PMID: 27698728; PMCID: PMC5038607.
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Cheminformatics-Based Anticoagulant Study of Traditionally Used Medicinal Plants.

Iranian biomedical journal

Alikhani Pour M, Sardari S, Eslamifar A, Azhar A, Rezvani M, Nazari M.
PMID: 28454485
Iran Biomed J. 2017 Nov;21(6):400-5. doi: 10.18869/acadpub.ibj.21.6.400. Epub 2017 Apr 29.

BACKGROUNG: Medicinal plants, as a complementary medicine, have been used to treat various diseases since ancient times. These plants have numerous beneficial applications and are the source of certain conventional drugs. In diseases such as stroke and ischemia, which...

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Alikhani Pour M, Sardari S, Eslamifar A, et al. Cheminformatics-Based Anticoagulant Study of Traditionally Used Medicinal Plants. Iran Biomed J. 2017;21(6):400-5doi: 10.18869/acadpub.ibj.21.6.400.
Alikhani Pour, M., Sardari, S., Eslamifar, A., Azhar, A., Rezvani, M., & Nazari, M. (2017). Cheminformatics-Based Anticoagulant Study of Traditionally Used Medicinal Plants. Iranian biomedical journal, 21(6), 400-5. https://doi.org/10.18869/acadpub.ibj.21.6.400
Alikhani Pour, Mahdi, et al. "Cheminformatics-Based Anticoagulant Study of Traditionally Used Medicinal Plants." Iranian biomedical journal vol. 21,6 (2017): 400-5. doi: https://doi.org/10.18869/acadpub.ibj.21.6.400
Alikhani Pour M, Sardari S, Eslamifar A, Azhar A, Rezvani M, Nazari M. Cheminformatics-Based Anticoagulant Study of Traditionally Used Medicinal Plants. Iran Biomed J. 2017 Nov;21(6):400-5. doi: 10.18869/acadpub.ibj.21.6.400. Epub 2017 Apr 29. PMID: 28454485; PMCID: PMC5572436.
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Liver regeneration after splenectomy in patients with liver cirrhosis.

Hepatology research : the official journal of the Japan Society of Hepatology

Yamada S, Morine Y, Imura S, Ikemoto T, Arakawa Y, Iwahashi S, Saito Y, Yoshikawa M, Teraoku H, Shimada M.
PMID: 26428414
Hepatol Res. 2016 Mar;46(5):443-9. doi: 10.1111/hepr.12573. Epub 2015 Oct 02.

AIM: Splenectomy is a well-known procedure to improve thrombocytopenia and liver function in patients with liver cirrhosis (LC). However, the effect of splenectomy on liver regeneration remains unclear. The aim of this study is to investigate the effect of...

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Yamada S, Morine Y, Imura S, et al. Liver regeneration after splenectomy in patients with liver cirrhosis. Hepatol Res. 2015;46(5):443-9doi: 10.1111/hepr.12573.
Yamada, S., Morine, Y., Imura, S., Ikemoto, T., Arakawa, Y., Iwahashi, S., Saito, Y., Yoshikawa, M., Teraoku, H., & Shimada, M. (2016). Liver regeneration after splenectomy in patients with liver cirrhosis. Hepatology research : the official journal of the Japan Society of Hepatology, 46(5), 443-9. https://doi.org/10.1111/hepr.12573
Yamada, Shinichiro, et al. "Liver regeneration after splenectomy in patients with liver cirrhosis." Hepatology research : the official journal of the Japan Society of Hepatology vol. 46,5 (2016): 443-9. doi: https://doi.org/10.1111/hepr.12573
Yamada S, Morine Y, Imura S, Ikemoto T, Arakawa Y, Iwahashi S, Saito Y, Yoshikawa M, Teraoku H, Shimada M. Liver regeneration after splenectomy in patients with liver cirrhosis. Hepatol Res. 2016 Mar;46(5):443-9. doi: 10.1111/hepr.12573. Epub 2015 Oct 02. PMID: 26428414.
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Factor V Leiden, Prothrombin and MTHFR Mutation in Patients with Preeclamsia, Intrauterine Growth Restriction and Placental Abruption.

Open access Macedonian journal of medical sciences

Livrinova V, Lega MH, Dimcheva AH, Samardziski I, Isjanovska R.
PMID: 27275292
Open Access Maced J Med Sci. 2015 Dec 15;3(4):590-4. doi: 10.3889/oamjms.2015.099. Epub 2015 Sep 18.

BACKGROUND: Factor V Leiden, Prothrombin and MTHFR gene mutation, could have an influence in pregnancy with adverse outcome Preeclamsia, IUGR and Placental abruption.AIM: The aim of this study is to investigate the presence of above mentioned inherited thrombophilias and...

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Livrinova V, Lega MH, Dimcheva AH, et al. Factor V Leiden, Prothrombin and MTHFR Mutation in Patients with Preeclamsia, Intrauterine Growth Restriction and Placental Abruption. Open Access Maced J Med Sci. 2015;3(4):590-4doi: 10.3889/oamjms.2015.099.
Livrinova, V., Lega, M. H., Dimcheva, A. H., Samardziski, I., & Isjanovska, R. (2015). Factor V Leiden, Prothrombin and MTHFR Mutation in Patients with Preeclamsia, Intrauterine Growth Restriction and Placental Abruption. Open access Macedonian journal of medical sciences, 3(4), 590-4. https://doi.org/10.3889/oamjms.2015.099
Livrinova, Vesna, et al. "Factor V Leiden, Prothrombin and MTHFR Mutation in Patients with Preeclamsia, Intrauterine Growth Restriction and Placental Abruption." Open access Macedonian journal of medical sciences vol. 3,4 (2015): 590-4. doi: https://doi.org/10.3889/oamjms.2015.099
Livrinova V, Lega MH, Dimcheva AH, Samardziski I, Isjanovska R. Factor V Leiden, Prothrombin and MTHFR Mutation in Patients with Preeclamsia, Intrauterine Growth Restriction and Placental Abruption. Open Access Maced J Med Sci. 2015 Dec 15;3(4):590-4. doi: 10.3889/oamjms.2015.099. Epub 2015 Sep 18. PMID: 27275292; PMCID: PMC4877892.
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Catridecacog: a breakthrough in the treatment of congenital factor XIII A-subunit deficiency?.

Journal of blood medicine

Korte W.
PMID: 25031548
J Blood Med. 2014 Jul 09;5:107-13. doi: 10.2147/JBM.S35395. eCollection 2014.

Circulating factor XIII (FXIII) consists of two active (A) and two carrier (B) subunits in tetrameric form. Congenital FXIII deficiency is a rare autosomal-recessive trait that mostly results from an FXIII A-subunit deficiency. Classic coagulation assays, such as prothrombin...

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Korte W. Catridecacog: a breakthrough in the treatment of congenital factor XIII A-subunit deficiency?. J Blood Med. 2014;5:107-13doi: 10.2147/JBM.S35395.
Korte, W. (2014). Catridecacog: a breakthrough in the treatment of congenital factor XIII A-subunit deficiency?. Journal of blood medicine, 5107-13. https://doi.org/10.2147/JBM.S35395
Korte, Wolfgang. "Catridecacog: a breakthrough in the treatment of congenital factor XIII A-subunit deficiency?." Journal of blood medicine vol. 5 (2014): 107-13. doi: https://doi.org/10.2147/JBM.S35395
Korte W. Catridecacog: a breakthrough in the treatment of congenital factor XIII A-subunit deficiency?. J Blood Med. 2014 Jul 09;5:107-13. doi: 10.2147/JBM.S35395. eCollection 2014. PMID: 25031548; PMCID: PMC4096448.
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Effects of cirrhosis on bone mineral density and bone metabolism.

The Eurasian journal of medicine

Turkeli M, Dursun H, Albayrak F, Okçu N, Uyanik MH, Uyanik A, Yıldırım R, Keleş M, Yılmaz O.
PMID: 25610017
Eurasian J Med. 2008 Apr;40(1):18-24.

OBJECTIVE: The present study was undertaken to examine the correlation between the severity of liver disease and the presence and severity of bone disease in patients with hepatic cirrhosis.MATERIALS AND METHODS: Between January 2005 and February 2006, 40 patients...

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Turkeli M, Dursun H, Albayrak F, et al. Effects of cirrhosis on bone mineral density and bone metabolism. Eurasian J Med. 2008;40(1):18-24
Turkeli, M., Dursun, H., Albayrak, F., Okçu, N., Uyanik, M. H., Uyanik, A., Yıldırım, R., Keleş, M., & Yılmaz, O. (2008). Effects of cirrhosis on bone mineral density and bone metabolism. The Eurasian journal of medicine, 40(1), 18-24.
Turkeli, Mehmet, et al. "Effects of cirrhosis on bone mineral density and bone metabolism." The Eurasian journal of medicine vol. 40,1 (2008): 18-24.
Turkeli M, Dursun H, Albayrak F, Okçu N, Uyanik MH, Uyanik A, Yıldırım R, Keleş M, Yılmaz O. Effects of cirrhosis on bone mineral density and bone metabolism. Eurasian J Med. 2008 Apr;40(1):18-24. PMID: 25610017; PMCID: PMC4261323.
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Prognostic significance of antithrombin activity in patients with crimean-congo hemorrhagic Fever.

The Eurasian journal of medicine

Ozkurt Z, Ozden K, Kiki I, Usanmaz M.
PMID: 25610169
Eurasian J Med. 2011 Aug;43(2):83-6. doi: 10.5152/eajm.2011.19.

OBJECTIVE: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral hemorrhagic fever. Disseminated intravascular coagulation (DIC) is an important complication of this disease, especially in severe and fatal cases. Antithrombin (AT) acts as an anticoagulant by inactivating thrombin, Factor IX,...

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Ozkurt Z, Ozden K, Kiki I, et al. Prognostic significance of antithrombin activity in patients with crimean-congo hemorrhagic Fever. Eurasian J Med. 2011;43(2):83-6doi: 10.5152/eajm.2011.19.
Ozkurt, Z., Ozden, K., Kiki, I., & Usanmaz, M. (2011). Prognostic significance of antithrombin activity in patients with crimean-congo hemorrhagic Fever. The Eurasian journal of medicine, 43(2), 83-6. https://doi.org/10.5152/eajm.2011.19
Ozkurt, Zulal, et al. "Prognostic significance of antithrombin activity in patients with crimean-congo hemorrhagic Fever." The Eurasian journal of medicine vol. 43,2 (2011): 83-6. doi: https://doi.org/10.5152/eajm.2011.19
Ozkurt Z, Ozden K, Kiki I, Usanmaz M. Prognostic significance of antithrombin activity in patients with crimean-congo hemorrhagic Fever. Eurasian J Med. 2011 Aug;43(2):83-6. doi: 10.5152/eajm.2011.19. PMID: 25610169; PMCID: PMC4261357.
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Global assays and the management of oral anticoagulation.

Thrombosis journal

Brinkman HJ.
PMID: 25762867
Thromb J. 2015 Feb 10;13:9. doi: 10.1186/s12959-015-0037-1. eCollection 2015.

Coagulation tests range from global or overall tests to assays specific to individual clotting factors and their inhibitors. Whether a particular test is influenced by an oral anticoagulant depends on the principle of the test and the type of...

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Brinkman HJ. Global assays and the management of oral anticoagulation. Thromb J. 2015;13:9doi: 10.1186/s12959-015-0037-1.
Brinkman, H. J. (2015). Global assays and the management of oral anticoagulation. Thrombosis journal, 139. https://doi.org/10.1186/s12959-015-0037-1
Brinkman, Herm Jan M. "Global assays and the management of oral anticoagulation." Thrombosis journal vol. 13 (2015): 9. doi: https://doi.org/10.1186/s12959-015-0037-1
Brinkman HJ. Global assays and the management of oral anticoagulation. Thromb J. 2015 Feb 10;13:9. doi: 10.1186/s12959-015-0037-1. eCollection 2015. PMID: 25762867; PMCID: PMC4355453.
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Rapid and early α-fetoprotein and des-γ-carboxy prothrombin responses to initial arterial infusion chemotherapy predict treatment outcomes of advanced hepatocellular carcinoma.

Molecular and clinical oncology

Oyama K, Koda M, Sugihara T, Kishina M, Miyoshi K, Okamoto T, Hodotsuka M, Fujise Y, Matono T, Tokunaga S, Okamoto K, Hosho K, Okano J, Murawaki Y.
PMID: 26137283
Mol Clin Oncol. 2015 May;3(3):655-662. doi: 10.3892/mco.2015.523. Epub 2015 Mar 03.

The aim of the present study was to predict the effects of transarterial infusion (TAI) chemotherapy based on early changes in α-fetoprotein (AFP) and des-γ-carboxy prothrombin (DCP) in patients with advanced hepatocellular carcinoma (HCC). Seventy-four patients who underwent TAI...

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Oyama K, Koda M, Sugihara T, et al. Rapid and early α-fetoprotein and des-γ-carboxy prothrombin responses to initial arterial infusion chemotherapy predict treatment outcomes of advanced hepatocellular carcinoma. Mol Clin Oncol. 2015;3(3):655-662doi: 10.3892/mco.2015.523.
Oyama, K., Koda, M., Sugihara, T., Kishina, M., Miyoshi, K., Okamoto, T., Hodotsuka, M., Fujise, Y., Matono, T., Tokunaga, S., Okamoto, K., Hosho, K., Okano, J., & Murawaki, Y. (2015). Rapid and early α-fetoprotein and des-γ-carboxy prothrombin responses to initial arterial infusion chemotherapy predict treatment outcomes of advanced hepatocellular carcinoma. Molecular and clinical oncology, 3(3), 655-662. https://doi.org/10.3892/mco.2015.523
Oyama, Kenji, et al. "Rapid and early α-fetoprotein and des-γ-carboxy prothrombin responses to initial arterial infusion chemotherapy predict treatment outcomes of advanced hepatocellular carcinoma." Molecular and clinical oncology vol. 3,3 (2015): 655-662. doi: https://doi.org/10.3892/mco.2015.523
Oyama K, Koda M, Sugihara T, Kishina M, Miyoshi K, Okamoto T, Hodotsuka M, Fujise Y, Matono T, Tokunaga S, Okamoto K, Hosho K, Okano J, Murawaki Y. Rapid and early α-fetoprotein and des-γ-carboxy prothrombin responses to initial arterial infusion chemotherapy predict treatment outcomes of advanced hepatocellular carcinoma. Mol Clin Oncol. 2015 May;3(3):655-662. doi: 10.3892/mco.2015.523. Epub 2015 Mar 03. PMID: 26137283; PMCID: PMC4471610.
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Showing 1 to 12 of 2268 entries